15-Methylhexadecenoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 15-Methylhexadecenoic acid
• 英文别名: (E)-15-methylhexadec-2-enoic acid
• 化学式: C₁₇H₃₂O₂
• 分子量: 268.4
• InChiKey: ROTVJTQFFYWWKB-FYWRMAATSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  19
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Group of anti-cancer compounds with specific structure and their production method
  申请人：——

  公开号：US20040034242A1

  公开（公告）日：2004-02-19

  Compounds containing a specific branched chain end terminal group, which is isopropyl, sec.-butyl, or tert.-butyl; a polar leading group; and long-chain aliphatic, non-cyclic, saturated or unsaturated, hydrocarbon group linking them; and having anti-cancer and immune boosting activity.

  具有抗癌和免疫增强活性的化合物，其包含特定的支链末端基团，即异丙基，仲丁基或叔丁基；极性前导基团；和连接它们的长链脂肪族、非环状、饱和或不饱和的碳氢基团。
• Small molecule anti-cancer compounds & related production process
  申请人：Yang, Zhenhua

  公开号：EP2361965A2

  公开（公告）日：2011-08-31

  A group of specific branched-chain fatty acids, with significant anticancer effects on human and animals; methods of making using either chemical synthesis or biosynthesis methods; and methods of treating cancer.

  对人类和动物具有显著抗癌作用的一组特定支链脂肪酸；使用化学合成或生物合成方法制造的方法；以及治疗癌症的方法。
• Production of fatty acids by heterologous expression of gene clusters from myxobacteria
  申请人：InterMed Discovery GmbH

  公开号：EP2390343A1

  公开（公告）日：2011-11-30

  The invention relates to a process for producing one or more polyunsaturated fatty acids by means of heterologous gene expression, the process comprising the steps: (i) providing a production organism which comprises a gene cluster encoding a polyunsaturated fatty acid biosynthetic pathway, said gene cluster - being derived from a source organism which differs from the production organism; and - encompassing a subsequence ER encoding an enoylreductase and a subsequence AT encoding an acyltransferase, wherein the subsequence AT is located downstream with respect to the subsequence ER; (ii) growing the production organism of step (i) in the presence of a fermentable carbon source whereby one or more polyunsaturated fatty acids are produced; and (iii) optionally, recovering the one or more polyunsaturated fatty acids.

  本发明涉及一种通过异源基因表达生产一种或多种多不饱和脂肪酸的工艺，该工艺包括以下步骤： (i) 提供一种生产生物体，该生物体包括一个编码多不饱和脂肪酸生物合成途径的基因簇，所述基因簇 - 来源于与生产生物体不同的来源生物体；以及 - 包括编码烯酰还原酶的子序列 ER 和编码酰基转移酶的子序列 AT，其中子序列 AT 位于子序列 ER 的下游； (ii) 在有可发酵碳源的情况下培养步骤(i)的生产生物体，从而产生一种或多种多不饱和脂肪酸；以及 (iii) 可选地回收一种或多种多不饱和脂肪酸。
• SMALL MOLECULE ANTICANCER COMPOUNDS AND RELATED PRODUCTION PROCESS
  申请人：Yang, Zhenhua

  公开号：EP1075533B1

  公开（公告）日：2014-12-31
• EP1075533A4
  申请人：——

  公开号：EP1075533A4

  公开（公告）日：2005-03-09