申请人:SEKISUI CHEMICAL CO., LTD.
公开号:EP1860436A1
公开(公告)日:2007-11-28
The present invention provides a blood coagulation accelerator excellent under severe conditions at ordinary or higher temperatures and capable of exhibiting high blood coagulation performance stably over a long period of time, as well as a container for blood examination wherein the blood coagulation accelerator is accommodated. Disclosed is a blood coagulation accelerator comprising an enzyme capable of hydrolyzing in a peptide chain a bond between arginine and an arbitrary amino acid residue and/or a bond between lysine and an arbitrary amino acid residue, an inactivated enzyme product comprising the above-mentioned enzyme inactivated by radiation irradiation, and β-alanine.
本发明提供了一种在普通或更高温度的严酷条件下性能优异并能长期稳定地表现出较高血液凝固性能的血液凝固促进剂,以及一种容纳血液凝固促进剂的血液检查容器。本发明公开了一种血液凝固促进剂,该促进剂由能够水解肽链中精氨酸与任意氨基酸残基之间的键和/或赖氨酸与任意氨基酸残基之间的键的酶、由通过辐射灭活的上述酶组成的灭活酶产物和β-丙氨酸组成。