trimethyl-[4-[(Z)-octadec-9-enoxy]-2-[(Z)-octadec-9-enoyl]oxy-4-oxobutyl]azanium;chloride

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: trimethyl-[4-[(Z)-octadec-9-enoxy]-2-[(Z)-octadec-9-enoyl]oxy-4-oxobutyl]azanium;chloride
• 化学式: C43H82ClNO4
• 分子量: 712.6
• InChiKey: KMLVCIHZUWQYQD-LQDDAWAPSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  9.62
• 重原子数：
  49
• 可旋转键数：
  38
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Esters of L-carnitine or alkanoyl L-carnitines useful as cationic lipids for the intracellular delivery of pharmacologically active compounds
  申请人：Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.

  公开号：US20040186175A1

  公开（公告）日：2004-09-23

  Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine and alkanoyl L-carnitines of formula (I) are also disclosed wherein the R groups are as defined in the description. 1

  描述了可用作阳离子脂质的左旋肉碱和烷酰左旋肉碱酯，用于细胞内输送药理活性化合物。还公开了式 (I) 的 L-肉碱和烷酰基 L-肉碱的新酯，其中 R 基团如描述中所定义。 1
• Esters of L-carnitine of alkanoyl L-carnitines useful as cationic lipids for the intracellular delivery of pharmacologically active compounds
  申请人：Pisano Claudio

  公开号：US20050079209A1

  公开（公告）日：2005-04-14

  Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine and alkanoyl L-carnitines of formula (I) are also disclosed wherein the R groups are as defined in the description.

  描述了可用作阳离子脂质的左旋肉碱和烷酰左旋肉碱酯，用于细胞内输送药理活性化合物。还公开了式 (I) 的 L-肉碱和烷酰基 L-肉碱的新酯，其中 R 基团如描述中所定义。
• ESTERS OF L-CARNITINE OR ALKANOYL L-CARNITINES
  申请人：SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A.

  公开号：EP1183228A2

  公开（公告）日：2002-03-06
• JP2002541238A
  申请人：——

  公开号：JP2002541238A

  公开（公告）日：2002-12-03
• [EN] ESTERS OF L-CARNITINE OR ALKANOYL L-CARNITINES USEFUL AS CATIONIC LIPIDS FOR THE INTRACELLULAR DELIVERY OF PHARMACOLOGICALLY ACTIVE COMPOUNDS<br/>[FR] ESTERS DE L-CARNITINE OU DE L-CARNITINES ALCANOYLES UTILISES COMME LIPIDES CATIONIQUES POUR UN APPORT INTRACELLULAIRE DE COMPOSES ACTIFS D'UN POINT DE VUE PHARMACOLOGIQUE
  申请人：SIGMA TAU IND FARMACEUTI

  公开号：WO2000061543A2

  公开（公告）日：2000-10-19

  Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine and alkanoyl L-carnitines of formula (I) are also disclosed wherein the R groups are as defined in the description.