Nitroso-l-arginine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Nitroso-l-arginine
• 英文别名: (2S)-5-(diaminomethylideneamino)-2-(2-oxohydrazinyl)pentanoic acid
• 化学式: C₆H₁₃N₅O₃
• 分子量: 203.2
• InChiKey: JJWNDJPMAQXKDS-BYPYZUCNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  143
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• MODIFIED APIDAECIN DERIVATIVES AS ANTIBIOTIC PEPTIDES
  申请人：Universitaet Leipzig

  公开号：US20150344524A1

  公开（公告）日：2015-12-03

  This invention relates to modified antibiotic peptides, particularly for use in medicine. The invention further relates to compositions and methods for destroying microorganisms, such as bacteria, viruses or fungi, and to methods for treating microbial infections. The object of the invention is to develop novel antibiotic peptides, particularly having enhanced antibiotic activity and an expanded spectrum of activity against other strains of bacteria, particularly gram-positive bacteria such as Staphylococcus aureus. According to the invention, the object is attained in a first aspect by a peptide according to claim 1.