异磷啉 | 253-37-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 金属杂环化合物
• 中文名称: 异磷啉
• 英文名称: 2-Phosphanaphthalin
• 英文别名: 2-Phosphonaphthalin-Radikal；isophosphinoline
• CAS: 253-37-2
• 化学式: C₉H₇P
• 分子量: 146.128
• InChiKey: ODZILJDRJCJHKM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-hydroxy-2-oxo-2,3-dihydro-1H-2λ5-isophosphinolin-4-one 生成 异磷啉
  参考文献：
  名称：

  2-磷萘

  摘要：

  报道了2-磷萘和三种甲基取代的衍生物的合成和物理性质，以及有关该体系反应性的一些观察结果。结论是这些化合物具有芳族特性。

  DOI：

  10.1016/0040-4020(75)80131-1

文献信息

• [EN] NOVEL ANTI-VIRAL AGENTS BASED UPON DERIVATIVES OF THE AROMATIC HETEROCYCLE PHENANTHRIDINE<br/>[FR] NOUVEAUX AGENTS ANTIVIRAUX FORMES A PARTIR DE DERIVES DE L'HETEROCYCLE AROMATIQUE PHENANTHRIDINE
  申请人：UNIV CALIFORNIA

  公开号：WO2005016343A1

  公开（公告）日：2005-02-24

  A series of substituted phenanthridine derivatives has been synthesized by converting the amines at the 3- and 8- positions of ethidium bromide into guanidine, pyrrole, urea, and various substituted ureas. The resulting derivatives exhibit unique spectral properties that change upon binding nucleic acids. The compounds have an enhanced affinity and specificity for HIV-1 Rev Response Element as compared to ethidium bromide.

  已经合成了一系列替代苯并喹啉衍生物，通过将溴乙锭中的3-位和8-位的胺基转化为胍嘧啶、吡咯、尿素和各种取代尿素。所得的衍生物表现出独特的光谱特性，在结合核酸时发生变化。与溴乙锭相比，这些化合物对HIV-1 Rev应答元件具有增强的亲和力和特异性。
• CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME
  申请人：Samsung Display Co., Ltd.

  公开号：US20190031614A1

  公开（公告）日：2019-01-31

  A condensed cyclic compound and an organic light-emitting device including the same are disclosed. According to an embodiment of the present disclosure, a condensed cyclic compound is represented by Formula 1:

  本发明公开了一种紧凑的环状化合物以及包括该化合物的有机发光器件。根据本发明的一种实施例，所述紧凑的环状化合物由公式1表示：
• N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of C-proteinase and for treating or preventing disorders related to unregulated collagen production
  申请人：——

  公开号：US20030191309A1

  公开（公告）日：2003-10-09

  The present invention relates to a novel class of organic molecules capable of inhibiting C-proteinase, and to their use to regulate, modulate and/or inhibit abnormal collagen formation as a therapeutic approach towards the treatment of fibrotic disorders.

  本发明涉及一种新型有机分子类，能够抑制C-蛋白酶，并且利用它们来调节、调节和/或抑制异常胶原形成，作为治疗纤维化疾病的治疗方法。
• Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders
  申请人：Kozikowski P. Alan

  公开号：US20070161640A1

  公开（公告）日：2007-07-12

  The present invention provides 4-substituted-2-azetidinone compounds, bicyclic 2-5-diketopiperazine compounds, and pharmaceutical compositions thereof that are potent, safe and effective neuroprotective agents. Due to their strong central nervous system (CNS) activity, the compounds can be used to enhance memory and to treat a variety of neurological disorders. The compounds are particularly useful for treating neurological disorders caused by, or associated with, CNS trauma.

  本发明提供了4-取代-2-氮杂环己酮化合物、双环2-5-二酮哌嗪化合物及其制备的药物组合物，这些化合物是强效、安全和有效的神经保护剂。由于它们具有强大的中枢神经系统(CNS)活性，这些化合物可用于增强记忆力并治疗多种神经系统疾病。这些化合物特别适用于治疗由CNS创伤引起或与之相关的神经系统疾病。
• NOVEL BORON COMPOUNDS, THEIR PRODUCTION PROCESSES, AND FUNCTIONAL ELECTRONIC DEVICES USING SAME
  申请人：Murakami Masahiro

  公开号：US20110046372A1

  公开（公告）日：2011-02-24

  The present invention provides novel boron compounds which are useful, depending on their characteristics, as light-emitting materials, electron-transport materials, electron-injection materials, hole-blocking materials, or organic semiconductor materials, and which have new molecular structures quite different from those of the heretofore known boron compounds; their production processes; and functional electronic devices using the same. The novel boron compounds are, for example, those of the following formula (1): These boron compounds can be produced by, for example, reacting boron compounds of the following formula (4): with compounds of the following formula (5): in the presence of a catalyst containing at least one metal element selected from the group consisting of palladium, platinum, and nickel. These boron compounds are used for the functional electronic devices.

  本发明提供了新型硼化合物，根据其特性，可以作为发光材料、电子传输材料、电子注入材料、阻挡空穴材料或有机半导体材料，并具有与迄今为止已知的硼化合物完全不同的新分子结构；它们的生产过程；以及使用它们的功能电子器件。新型硼化合物例如为以下式子（1）的化合物：这些硼化合物可以通过例如在至少包含铂、钯和镍组成的金属元素中选择至少一种催化剂的存在下，将以下式子（4）的硼化合物与以下式子（5）的化合物反应制备而成。这些硼化合物用于功能电子器件。

表征谱图