1,1,3,3-四氟-2-(氟甲氧基)-3-甲氧基丙-1-烯 | 111607-90-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 中文名称: 1,1,3,3-四氟-2-(氟甲氧基)-3-甲氧基丙-1-烯
• 英文名称: 1,1,3,3-Tetrafluoro-2-fluoromethoxy-3-methoxy-propene
• 英文别名: 1,1,3,3-Tetrafluoro-2-(fluoromethoxy)-3-methoxyprop-1-ene；1,1,3,3-tetrafluoro-2-(fluoromethoxy)-3-methoxyprop-1-ene
• CAS: 111607-90-0
• 化学式: C₅H₅F₅O₂
• 分子量: 192.086
• InChiKey: XTVGIFUYYGEGEK-UHFFFAOYSA-N

物化性质

• 沸点：
  139.2±40.0 °C(Predicted)
• 密度：
  1.331±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  七氟烷 在 soda lime 作用下， 反应 0.67h， 生成 氟甲基 2-甲氧基-2,2-二氟-1-(三氟甲基)乙基醚 、 1,1,3,3,3-五氟-2-(氟甲氧基)-1-丙烯 、 (Z)-1,3,3,3-Tetrafluoro-2-fluoromethoxy-1-methoxy-propene 、 1,1,3,3-四氟-2-(氟甲氧基)-3-甲氧基丙-1-烯
  参考文献：
  名称：

  Fluoro-dideutero-methyl 1,1,1,3,3,3-hexafluoroisopropyl ether (D2-sevoflurane) reactions on soda lime: deuterium content of deuterated sevoflurane and its volatile degradation products

  摘要：

  The degradation of the experimental anesthetic, fluoro-dideutero-methyl 1,1,1,3,3,3-hexafluoroisopropyl ether (D-2-sevoflurane) on soda lime (Sodasorb((R))) has been compared with sevoflurane and examined in regard to product deuterium content. Similar products and rates of degradation were found between sevoflurane and D-2-sevoflurane, and all D-2-sevoflurane products contained the fluorodideuteromethoxy group. Four products contained a trideuteromethoxy moiety, indicating the addition of methanol derived from the fluoromethoxy carbon of D-2-sevoflurane.

  DOI：

  10.1016/0022-1139(94)03152-p

文献信息

• Fluoro-dideutero-methyl 1,1,1,3,3,3-hexafluoroisopropyl ether (D2-sevoflurane) reactions on soda lime: deuterium content of deuterated sevoflurane and its volatile degradation products
  作者：Jan A. Ruzicka、Max T. Baker

  DOI：10.1016/0022-1139(94)03152-p

  日期：1995.3

  The degradation of the experimental anesthetic, fluoro-dideutero-methyl 1,1,1,3,3,3-hexafluoroisopropyl ether (D-2-sevoflurane) on soda lime (Sodasorb((R))) has been compared with sevoflurane and examined in regard to product deuterium content. Similar products and rates of degradation were found between sevoflurane and D-2-sevoflurane, and all D-2-sevoflurane products contained the fluorodideuteromethoxy group. Four products contained a trideuteromethoxy moiety, indicating the addition of methanol derived from the fluoromethoxy carbon of D-2-sevoflurane.