1,2,3,4-四氯丁烷 | 3405-32-1

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 中文名称: 1,2,3,4-四氯丁烷
• 英文名称: 1,2,3,4-tetrachlorobutane
• 英文别名: 1,2,3,4-Tetrachlor-butan；dl-1,2,3,4-Tetrachlorbutan；meso-1,2,3,4-tetrachlorobutane
• CAS: 3405-32-1
• 化学式: C₄H₆Cl₄
• mdl: MFCD00000945
• 分子量: 195.904
• InChiKey: IXZVKECRTHXEEW-UHFFFAOYSA-N

物化性质

• 熔点：
  28.17°C (estimate)
• 沸点：
  191.03°C (estimate)
• 密度：
  1.3920 (estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 危险等级：
  6.1(b)
• 危险品运输编号：
  UN 2811
• 海关编码：
  2903199000
• 包装等级：
  III
• 危险类别：
  6.1(b)

反应信息

• 作为反应物：
  描述：

  1,2,3,4-四氯丁烷 在 氢氟酸 作用下， 生成 3-chloro-2-fluorobuta-1,3-diene
  参考文献：
  名称：

  2，3-二氟丁二烯和2-氯-3-氟丁二烯的聚合

  摘要：

  DOI：

  10.1021/ie50502a051
• 作为产物：
  描述：

  1,2-丁二烯 在 二氯化硫 、 Petroleum ether 作用下， 生成 1,2,3,4-四氯丁烷
  参考文献：
  名称：

  Backer; Strating, Recueil des Travaux Chimiques des Pays-Bas, 1935, vol. 54, p. 52,54

  摘要：

  DOI：

文献信息

• PROCESS FOR PRODUCTION OF 2,3-DICHLOROBUTADIENE-1,3
  申请人：REDWINE TERRY WAYNE

  公开号：US20090163745A1

  公开（公告）日：2009-06-25

  2,3-dichlorobutadiene-1,3 of high purity is produced from 1,2,3,4-tetrachlorobutane by a process comprising the steps of dehydrochlorination, chlorination of the reaction product obtained in the dehydrochlorination step and subsequent separation of a 2,3-dichlorobutadiene-1,3 composition from the reaction product of the chlorination step.

  高纯度的2,3-二氯丁二烯-1,3是通过从1,2,3,4-四氯丁烷中经过脱氯化、氯化脱氯化步骤得到的反应产物进行氯化，然后从氯化步骤的反应产物中分离出2,3-二氯丁二烯-1,3组成的过程来生产的。
• Oxygen-containing heterocyclic fused naphthopyrans
  申请人：Vision-Ease Lens, Inc.

  公开号：US20040215024A1

  公开（公告）日：2004-10-28

  This invention relates to novel naphthopyrans having an oxygen-containing heterocyclic group F annelated on the i, j, or k side of the naphthopyran ring, having certain substituents at the 2, 5, and 6 positions of the naphthopyran ring. These naphthopyrans may have the formula (I) presented below: 1 These compounds (I) have interesting photochromic properties. Also related to this invention are host materials that contain such naphthopyran compounds, and articles such as ophthalmic lenses or other plastic transparencies that incorporate the naphthopyran compounds.

  这项发明涉及具有氧含杂环基团F的新型萘并吡喹啉，该基团F附加在萘并吡喹啉环的i、j或k侧，萘并吡喹啉环的2、5和6位具有特定取代基。这些萘并吡喹啉可能具有如下所示的化学式（I）： 这些化合物（I）具有有趣的光致变色性质。与此发明相关的还有含有这种萘并吡喹啉化合物的宿主材料，以及包含这种萘并吡喹啉化合物的眼镜镜片或其他塑料透明物品。
• Method for producing organic compounds by substituting halogen atoms
  申请人：MITSUI CHEMICALS, INC.

  公开号：EP1486479A1

  公开（公告）日：2004-12-15

  The invention pertains to a method in which a halogen atom of an organic compound is replaced with a group derived from a nucleophilic agent, at high yield and high efficiency, by the following method which includes a step of reacting the nucleophilic agent with an organic material having a halogen atom bonded to a carbon atom having four σ bonds, more specifically: a method for producing an organic compound having Q, the method including a step of reacting a compound represented by general formula (2) with an organic starting material having at least one halogen atom bonded to a carbon atom having four σ bonds so as to replace the halogen atom in the organic starting material with Q:         MQa     (2) (wherein M represents an alkali metal atom, an alkali earth metal atom, or a rare earth metal atom; Q represents a moiety of an inorganic acid or an active hydrogen compound derived by eliminating a proton, wherein Q is a halogen atom different from the halogen atom in the organic starting material having the halogen atom bonded to the carbon atom having the four σ bonds; and a represents an integer of 1 to 3) in the presence of a compound represented by general formula (1) (wherein Z- represents an anion derived by eliminating a proton from an inorganic acid or an active hydrogen compound; R2 is the same or different; R2 each independently represent a C1-C10 hydrocarbon group or two R2 on the same nitrogen atom may be bonded with each other to form a ring with the nitrogen atom).

  这项发明涉及一种方法，其中有机化合物中的卤素原子被来自亲核试剂的基团取代，且产率高效率高，通过以下方法实现，包括以下步骤：将亲核试剂与具有与碳原子形成四个σ键的卤素原子相结合的有机材料反应的步骤，更具体地说：一种用于生产具有Q的有机化合物的方法，包括以下步骤：将由通式（2）表示的化合物与至少一个卤素原子与碳原子形成四个σ键的有机起始材料反应，以将有机起始材料中的卤素原子替换为Q：         MQa     (2) （其中M代表碱金属原子、碱土金属原子或稀土金属原子；Q代表由消除质子衍生的无机酸或活性氢化合物的基团，其中Q是不同于有机起始材料中卤素原子的卤素原子，该卤素原子与具有四个σ键的碳原子相结合；a表示1到3的整数），在通式（1）表示的化合物的存在下 （其中Z-代表由无机酸或活性氢化合物中消除质子衍生的阴离子；R2相同或不同；R2各自独立地表示C1-C10烃基，或者两个R2在同一氮原子上可能与彼此结合形成与氮原子的环）。
• [EN] AN IMPROVED PROCESS FOR THE PREPARATION OF 2,3,-DICHLORO 1,3,BUTADIENE FROM 1,3 BUTADIENE<br/>[FR] PROCÉDÉ AMÉLIORÉ POUR LA PRÉPARATION DE 2,3-DICHLORO-1,3-BUTADIÈNE À PARTIR DE 1,3-BUTADIÈNE
  申请人：PIDILITE IND LTD

  公开号：WO2011058575A1

  公开（公告）日：2011-05-19

  The present invention relates to an improved process for the production of 2,3-Dichloro 1,3-Butadiene which comprises Chlorinating Butadiene, in liquid phase, in the presence of chlorinated solvents & phase transfer catalyst, Distilling the solvent, Distilling the formed 3,4-dichlorobutene-1, 1,4-dichlorobutene-2; and 1,2,3,4-Tetrachlorbutane; under reduced pressure,chlorinating the separated 3,4-dichlorobutene-1 and 1,4-dichlorobutene-2 to give 1,2,3,4-Tetrachlorobutane.,double Dehydrochlorinating the 1,2,3,4-Tetrachlorobutane using methanol,alkali and inhibitors under atmosphere of 1% oxides of nitrogen in nitrogen atmosphere the total period of Dehydrochlorinating being in the range of 15-33 hours to give 2,3-Dichloro 1,3-Butadiene and separating methanol to get 2,3-Dichloro 1,3-Butadiene

  本发明涉及一种改进的生产2,3-二氯-1,3-丁二烯的方法，包括在液相中存在氯化溶剂和相转移催化剂的情况下氯化丁二烯，蒸馏溶剂，蒸馏形成的3,4-二氯丁烯-1，1,4-二氯丁烯-2和1,2,3,4-四氯丁烷；在减压下氯化分离的3,4-二氯丁烯-1和1,4-二氯丁烯-2以得到1,2,3,4-四氯丁烷，使用甲醇、碱和抑制剂双脱氯化1,2,3,4-四氯丁烷，在含有1%氮氧化物的氮气氛围下进行总脱氯化时间范围在15-33小时，得到2,3-二氯-1,3-丁二烯并分离甲醇以获得2,3-二氯-1,3-丁二烯。
• PRODUCTION PROCESS AND PURIFICATION PROCESS FOR 1,2,3,4-TETRACHLOROHEXAFLUOROBUTANE
  申请人：Ohno Hiromoto

  公开号：US20110071325A1

  公开（公告）日：2011-03-24

  It is an object of the present invention to provide a process for producing 1,2,3,4-tetrachlorohexafluorobutane industrially inexpensively and efficiently by utilizing expensive fluorine gas efficiently and to provide a process which is capable of stably producing 1,2,3,4-tetrachlorohexafluorobutane and in which, by carrying out fluorination reaction at a low temperature, side reactions such as formation of a low-boiling substance due to cleavage of C—C bonds and formation of an excess fluoride are difficult to occur. The process for producing 1,2,3,4-tetrachlorohexafluorobutane of the present invention is characterized in that it includes feeding fluorine gas to 1,2,3,4-tetrachlorobutane using plural reactors in the presence of a solvent and in the absence of a catalyst to allow the 1,2,3,4-tetrachlorobutane and the fluorine gas to react with each other, wherein a part or all of unreacted fluorine gas discharged from one reactor is introduced into a reactor different from said one reactor.

  本发明的目的是提供一种工业上廉价高效地生产1,2,3,4-四氯六氟丁烷的方法，通过有效利用昂贵的氟气，并提供一种能够稳定生产1,2,3,4-四氯六氟丁烷的方法，在低温下进行氟化反应，难以发生C-C键裂解形成低沸点物质和过量氟化物的副反应。本发明的1,2,3,4-四氯六氟丁烷生产方法的特点在于，在溶剂存在的情况下，在缺乏催化剂的情况下，将氟气输入到1,2,3,4-四氯丁烷中，使用多个反应器使1,2,3,4-四氯丁烷和氟气相互反应，其中从一个反应器排放的未反应氟气的一部分或全部被引入到不同于该反应器的另一个反应器中。

表征谱图