N-[(E)-(3-methoxy-4-{2-[2-(prop-2-en-1-yl)phenoxy]ethoxy}phenyl)methylidene]-4H-1,2,4-triazol-4-amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-[(E)-(3-methoxy-4-{2-[2-(prop-2-en-1-yl)phenoxy]ethoxy}phenyl)methylidene]-4H-1,2,4-triazol-4-amine
• 英文别名: (E)-1-[3-methoxy-4-[2-(2-prop-2-enylphenoxy)ethoxy]phenyl]-N-(1,2,4-triazol-4-yl)methanimine
• 化学式: C₂₁H₂₂N₄O₃
• 分子量: 378.4
• InChiKey: PLDIHXRGKGRTJN-ZVHZXABRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  28
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  70.8
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Method for Treating Androgen Receptor Positive Cancers
  申请人：Gurova Katerina

  公开号：US20120264771A1

  公开（公告）日：2012-10-18

  Provided is a method of inhibiting growth of androgen receptor positive cancer cells. The method entails administering to an individual diagnosed with or suspected of having an androgen receptor positive cancer and administering to the individual a composition containing a compound that can inhibit the growth of the androgen receptor positive cancer.
• US8835447B2
  申请人：——

  公开号：US8835447B2

  公开（公告）日：2014-09-16
• [EN] METHOD FOR TREATING ANDROGEN RECEPTOR POSITIVE CANCERS<br/>[FR] MÉTHODE POUR LE TRAITEMENT DE CANCERS POSITIFS AUX RÉCEPTEURS DES ANDROGÈNES
  申请人：HEALTH RESEARCH INC

  公开号：WO2011050353A1

  公开（公告）日：2011-04-28

  Provided is a method of inhibiting growth of androgen receptor positive cancer cells. The method entails administering to an individual diagnosed with or suspected of having an androgen receptor positive cancer and administering to the individual a composition containing a compound that can inhibit the growth of the androgen receptor positive cancer.