抗氧剂 1035 | 41484-35-9

• 物质功能分类: 催化剂及助剂 - 抗氧剂
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 抗氧剂 1035
• 中文别名: 硫代二乙撑双[3-(3,5-二叔丁基-4-羟基苯基)丙酸酯]；3,5-双(1,1-二甲基乙基)-4-羟基苯丙酸硫代二-2,1-乙二醇酯；2,2'-亚硫基乙二醇双[3-(3,5-二叔丁基-4-羟基苯基)丙酸酯]；抗氧剂1035；二[3,5-二-(1,1-二甲基乙基)-4-羟基-]苯丙酸硫杂二甘醇酯；2,2'-硫代二乙基双[3-(3,5-二叔丁基-4-羟苯基)丙酸酯]；抗氧剂 135
• 英文名称: 2,2-thiodiethylene bis<3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate>
• 英文别名: thiodiethyl bis<3-(3',5'-di-tert-butyl-4'-hydroxyphenyl)propionate>；2-[2-[3-(4-hydroxy-3,5-di-tert-butyl-phenyl)propanoyloxy]ethylsulfanyl]ethyl 3-(4-hydroxy-3,5-di-tert-butyl-phenyl)propanoate；thiodiethylene bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate]；irganox 1035；bis(2-[3-(3,5-di-tert-butyl-4-hydroxy-phenyl)-propionyloxy]-ethyl) sulfide, irganox 288；3-thiapentane-1,5-diyl bis[3-[3,5-bis(tert-butyl)-4-hydroxyphenyl]propanoate]；thiodiethylene bis-(3,5-di-tert-butyl-4-hydroxy hydrocinnamate)；thiodiethylene bis(3,5-di-t-butyl-4-hydroxy)hydrocinnamate；2-[2-[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyloxy]ethylsulfanyl]ethyl 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate
• CAS: 41484-35-9
• 化学式: C₃₈H₅₈O₆S
• mdl: MFCD00059346
• 分子量: 642.941
• InChiKey: VFBJXXJYHWLXRM-UHFFFAOYSA-N

物化性质

• 熔点：
  78 °C
• 沸点：
  659.4±55.0 °C(Predicted)
• 密度：
  1.072±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于DMSO（少许）、甲醇（少许）
• 物理描述：
  DryPowder; DryPowder, PelletsLargeCrystals, OtherSolid; OtherSolid; OtherSolid, Liquid
• 稳定性/保质期：
  常规情况下不会分解，也没有危险反应。

计算性质

• 辛醇/水分配系数(LogP)：
  10.4
• 重原子数：
  45
• 可旋转键数：
  18
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  118
• 氢给体数：
  2
• 氢受体数：
  7

ADMET

毒理性

• 毒性数据

LC50 (大鼠) = 6,300 毫克/立方米/4小时

LC50 (rat) = 6,300 mg/m3/4hr

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

安全信息

• RTECS号：
  DA8342500
• 海关编码：
  2930909090
• 包装等级：
  III
• 危险类别：
  9
• 危险性防范说明：
  P264,P270,P273,P280,P301+P312+P330,P302+P352+P312,P305+P351+P338+P310,P332+P313,P391,P501
• 危险品运输编号：
  3077
• 危险性描述：
  H302+H312,H315,H318,H411
• 储存条件：
  密封、阴凉、干燥保存。

SDS

2,2'-Thiodiethylene Bis[3-(3,5-di-tert-butyl-4- Revision number: 5
hydroxyphenyl)propionate]
SAFETY DATA SHEET

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Section 1. IDENTIFICATION
Product name: 2,2'-Thiodiethylene Bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate]

Revision number: 5

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Section 2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDS Not classified
Not classified
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS Not classified
GHS label elements, including precautionary statements
Pictograms or hazard symbols None
Signal word No signal word
Hazard statements None
Precautionary statements: None

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance
Substance/mixture:
Components: 2,2'-Thiodiethylene Bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate]
>98.0%(LC)(T)
Percent:
CAS Number: 41484-35-9
Chemical Formula: C38H58O6S

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Section 4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
Remove/Take off immediately all contaminated clothing. Rinse skin with
Skin contact:
water/shower. If skin irritation or rash occurs: Get medical advice/attention.
Rinse cautiously with water for several minutes. Remove contact lenses, if present
Eye contact:
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion: Get medical advice/attention if you feel unwell. Rinse mouth.
Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

---

Section 5. FIRE-FIGHTING MEASURES
Suitable extinguishing Dry chemical, foam, water spray, carbon dioxide.
media:
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
generate poisonous fume.
from the chemical:
2,2'-Thiodiethylene Bis[3-(3,5-di-tert-butyl-4-
hydroxyphenyl)propionate]

---

Section 5. FIRE-FIGHTING MEASURES
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

---

Section 6. ACCIDENTAL RELEASE MEASURES
Use personal protective equipment. Keep people away from and upwind of spill/leak.
Personal precautions,
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Handling is performed in a well ventilated place. Wear suitable protective equipment.
Technical measures:
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions: Keep container tightly closed. Store in a cool and dark place.
Store away from incompatible materials such as oxidizing agents.
Packaging material: Comply with laws.

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Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Install a closed system or local exhaust as possible so that workers should not be
Engineering controls:
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection: Protective gloves.
Eye protection: Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

---

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Solid
Form: Crystal- Powder
White - Almost white
Colour:
Odour: No data available
pH: No data available
Melting point/freezing point:78°C
No data available
Boiling point/range:
Flash point: No data available
Flammability or explosive
limits:
No data available
Lower:
Upper: No data available
No data available
Relative density:
Solubility(ies):
No data available
[Water]
[Other solvents] No data available
2,2'-Thiodiethylene Bis[3-(3,5-di-tert-butyl-4-
hydroxyphenyl)propionate]

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Section 10. STABILITY AND REACTIVITY
Chemical stability: Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Sulfur oxides
products:

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Section 11. TOXICOLOGICAL INFORMATION
orl-rat LD50:6300 mg/kg
Acute Toxicity:
Skin corrosion/irritation: No data available
No data available
Serious eye
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
No data available
IARC =
NTP = No data available
No data available
Reproductive toxicity:
RTECS Number: DA8342500

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Section 12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence / degradability: No data available
Bioaccumulative No data available
potential(BCF):
Mobility in soil
Log Pow: No data available
Soil adsorption (Koc): No data available
Henry's Law No data available
constant(PaM3/mol):

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Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

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Section 14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
UN-No: Not listed

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Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.
2,2'-Thiodiethylene Bis[3-(3,5-di-tert-butyl-4-
hydroxyphenyl)propionate]

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

物理特性

• 外观：白色粉末
• 透光率：
  • 425nm ≥95%
  • 500nm ≥97%
• 挥发分：≤0.1%
• 灰 分：≤0.2%
• 熔 点：63℃ - 68℃
• 溶解性：清澈
• 含量：≥99%

应用

抗氧化剂1035是一种性能良好的硫醚型受阻酚类抗氧化剂，广泛应用于各种塑料、橡胶、涂料，也可用于ABS、PS、PU、PA等材料中，具有良好的抗氧化效果。

反应信息

• 作为反应物：
  描述：

  二碳酸二叔丁酯 、 抗氧剂 1035 在 4-二甲氨基吡啶 作用下， 以 乙腈 为溶剂， 反应 2.0h， 以94%的产率得到2-[2-[3-[3,5-Ditert-butyl-4-[(2-methylpropan-2-yl)oxycarbonyloxy]phenyl]propanoyloxy]ethylsulfanyl]ethyl 3-[3,5-ditert-butyl-4-[(2-methylpropan-2-yl)oxycarbonyloxy]phenyl]propanoate
  参考文献：
  名称：

  組成物、硬化膜、カラーフィルタ、カラーフィルタの製造方法、液晶表示装置、発光表示装置、及び熱潜在性ラジカル捕捉剤

  摘要：

  这是一项关于抑制高温加热前后色差的组合物、使用该组合物形成的固化膜、使用该组合物形成的彩色滤光片、具有该彩色滤光片的液晶显示装置和发光显示装置，以及提供一种新的热潜在性自由基捕获剂，其通过加热脱除保护并发挥功能的专利。解决方案包括含有（A）由一般式（1）表示的化合物、（B）粘合剂成分和（C）溶剂的组合物。（其中Q为S或O；R1和R2分别独立地是卤素原子、烷基、芳基烷基、酰基、烷氧基或烷基硫基）。

  公开号：

  JP2018024616A
• 作为产物：
  描述：

  2-chloroethyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate 在 sodium sulfide 、 苯基三甲基溴化铵 作用下， 以 乙醇 为溶剂， 反应 2.0h， 以95%的产率得到抗氧剂 1035
  参考文献：
  名称：

  硫代二乙撑双[3-(3,5-二叔丁基-4-羟基苯基)丙酸酯]的合成方法

  摘要：

  本发明涉及一种硫代二乙撑双[3‑(3,5‑二叔丁基‑4‑羟基苯基)丙酸酯]的合成方法。所述方法使2,6‑二叔丁基苯酚与丙烯酸酯反应并继续与2‑氯乙醇反应，得到中间体3‑(3,5‑二叔丁基‑4‑四羟基苯基)丙酸2‑氯乙酯；然后在季铵盐存在下，与硫化钠反应制得目标产物。本发明合成方法的具有工艺简单、产物收率高、纯度高的优点，特别适合在工业生产中应用。

  公开号：

  CN114213291B

文献信息

• METHOD FOR PRODUCING TRANS-BIS(AMINOMETHYL)CYCLOHEXANE, METHOD FOR PRODUCING BIS(ISOCYANATOMETHYL)CYCLOHEXANE, BIS(ISOCYANATOMETHYL)CYCLOHEXANE, POLYISOCYANATE COMPOSITION, AND POLYURETHANE RESIN
  申请人：MITSUI CHEMICALS, INC.

  公开号：US20160207875A1

  公开（公告）日：2016-07-21

  A method for producing trans-bis(aminomethyl)cyclohexane includes a trans-isomerization step in which cis-dicyanocyclohexane is isomerized into trans-dicyanocyclohexane by heating dicyanocyclohexane containing cis-dicyanocyclohexane in the presence of a tar component produced by distillation of dicyanocyclohexane; and an aminomethylation step in which trans-dicyanocyclohexane produced by the trans-isomerization step is allowed to contact with hydrogen to produce trans-bis(aminomethyl)cyclohexane.

  生产反式-双(氨甲基)环己烷的方法包括以下步骤：在一个反式异构化步骤中，通过加热含有顺-二氰基环己烷的二氰基环己烷，在二氰基环己烷的蒸馏产生的焦油组分的存在下，将顺-二氰基环己烷异构化为反-二氰基环己烷；以及在一个氨甲基化步骤中，通过让通过反式异构化步骤产生的反-二氰基环己烷与氢接触来产生反式-双(氨甲基)环己烷。
• POLYMERIZABLE COMPOUNDS
  申请人：Bremer Matthias

  公开号：US20090141215A1

  公开（公告）日：2009-06-04

  The present invention relates to novel polymerizable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, especially in LC displays of the PS (polymer-stabilized) and PSA (polymer-sustained alignment) type.

  本发明涉及新型可聚合化合物，以及用于制备其的过程和中间体，以及其在光学、电光和电子方面的用途，特别是在液晶（LC）介质和LC显示器中的应用，尤其是在PS（聚合物稳定）和PSA（聚合物维持对齐）类型的LC显示器中的应用。
• Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith
  申请人：——

  公开号：US20030004235A1

  公开（公告）日：2003-01-02

  2H-Benzotriazole UV absorbers substituted at the 3-position and/or the 5-position of the phenyl ring by a phenyl moiety which is substituted by a heteroatom are particularly photostable in automotive coatings, and are of low color and exhibit low volatility in thermoplastic compositions.

  3-位和/或5-位被苯基环上的苯基取代的2H-苯并三唑紫外线吸收剂，其被异原子取代的苯基特别在汽车涂料中具有光稳定性，并且在热塑性复合材料中具有低色度和低挥发性。
• POLYMERIZABLE COMPOUND AND OPTICAL ISOMER
  申请人：DIC Corporation

  公开号：US20180022716A1

  公开（公告）日：2018-01-25

  The present invention provides a polymerizable compound having high storage stability without causing crystal precipitation when added to a polymerizable composition. The present invention also provides a polymerizable composition containing the compound. When the filmy polymer produced through polymerization of the polymerizable composition is irradiated with UV light, it hardly discolors or peels from substrate. Further, the present invention provides a polymer produced through polymerization of the polymerizable composition and an optically anisotropic body using the polymer.

  本发明提供了一种聚合物化合物，具有高储存稳定性，添加到聚合物化合物时不会导致结晶沉淀。本发明还提供了含有该化合物的聚合物化合物。当通过聚合物化合物的聚合产生薄膜状聚合物时，若用紫外光照射，它几乎不会变色或脱落。此外，本发明提供了通过聚合物化合物的聚合产生的聚合物，以及使用该聚合物的光学各向异性体。
• POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS
  申请人：Taugerbeck Andreas

  公开号：US20130093975A1

  公开（公告）日：2013-04-18

  The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, especially in LC displays of the PS (“polymer sustained”) or PSA (“polymer sustained alignment”) type.

  本发明涉及可聚合化合物，以及用于其制备的工艺和中间体，以及其在光学、电光和电子方面的用途，特别是在液晶（LC）介质和LC显示器中的应用，特别是在PS（“聚合物持续”）或PSA（“聚合物持续取向”）类型的LC显示器中的应用。