1,5-环辛二烯,1,5-二溴- | 158834-31-2

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 中文名称: 1,5-环辛二烯,1,5-二溴-
• 英文名称: 1,5-dibromo-1,5-cyclooctadiene
• 英文别名: 1,5-dibromocycloocta-1,5-diene；1,5-Dibromocycloocta-1,5-diene
• CAS: 158834-31-2
• 化学式: C₈H₁₀Br₂
• 分子量: 265.975
• InChiKey: ZOHNJFPKANRXOY-UHFFFAOYSA-N

物化性质

• 沸点：
  289.6±40.0 °C(Predicted)
• 密度：
  1.735±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,5-环辛二烯,1,5-二溴- 、 alkaline earth salt of/the/ methylsulfuric acid 在 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) 作用下， 以 乙醚 为溶剂， 反应 3.5h， 以90%的产率得到1,5-二甲基-1,5-环辛二烯
  参考文献：
  名称：

  Chirality Control of Tropos Diphenylmethane-Derived Phosphoramidites by Chiral Dienes: Its Application to Asymmetric Michael Addition

  摘要：

  The Rh complex of tropos diphenylmethane-derived phosphoramidite could be chirally controlled to adopt single chiral conformation upon addition of a chiral diene. In the asymmetric Michael addition of alpha-cyanocarboxylates catalyzed by the Rh complexes, the chiral diene and bisphenylmethane-derived phosphoramidite functioned to attain higher enantioselectivity and catalytic activity via asymmetric activation.

  DOI：

  10.3987/com-08-s(f)102

文献信息

• Molecular clips and tweezers with corannulene pincers
  作者：Lesya Kobryn、William P. Henry、Frank R. Fronczek、Renata Sygula、Andrzej Sygula

  DOI：10.1016/j.tetlet.2009.09.177

  日期：2009.12

  Application of the synthetic methodology developed in our laboratory yields molecular clips and tweezers with corannulene pincers and cyclooctadiene or cyclooctatetraene tethers. These highly nonplanar systems possess a potential for binding guest molecules of various sizes. One of the clips, bis(benzocorannulene)[a,e]cyclooctadiene, exists in a 'open' chair conformation encapsulating solvating nitrobenzene in the solid state, while it is expected to prefer an internally pi-pi stacked twist-boat conformation in the gas phase. (c) 2009 Elsevier Ltd. All rights reserved.
• Chirality Control of Tropos Diphenylmethane-Derived Phosphoramidites by Chiral Dienes: Its Application to Asymmetric Michael Addition
  作者：Koichi Mikami、Kazuki Wakabayashi、Kohsuke Aikawa

  DOI：10.3987/com-08-s(f)102

  日期：——

  The Rh complex of tropos diphenylmethane-derived phosphoramidite could be chirally controlled to adopt single chiral conformation upon addition of a chiral diene. In the asymmetric Michael addition of alpha-cyanocarboxylates catalyzed by the Rh complexes, the chiral diene and bisphenylmethane-derived phosphoramidite functioned to attain higher enantioselectivity and catalytic activity via asymmetric activation.