(3R)-3-(ethylamino)pyrrolidine-2,5-dione

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (3R)-3-(ethylamino)pyrrolidine-2,5-dione
• 化学式: C₆H₁₀N₂O₂
• 分子量: 142.16
• InChiKey: XLNDPYUHSNCDIZ-SCSAIBSYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Catalysts and methods for enantioselective conjugate additions of amines to unsaturated electrophiles
  申请人：Northwestern University

  公开号：US10781172B2

  公开（公告）日：2020-09-22

  Disclosed are complexes and methods of using the complexes as catalysts for addition of amines to unsaturated electrophiles, as well as novel compounds produced by the disclosed complexes and methods. The disclosed methods may utilize the disclosed complexes as catalysts for adding unprotected primary amines and secondary amines to unsaturated electrophiles in an enantioselective manner to produce novel compounds which may include amino substituted succinimide compounds.

  所公开的是络合物和使用络合物作为催化剂将胺加到不饱和亲电体上的方法，以及用所公开的络合物和方法生产的新型化合物。所公开的方法可利用所公开的络合物作为催化剂，以对映选择性的方式将未保护的伯胺和仲胺添加到不饱和亲电体中，从而生产出新型化合物，其中可包括氨基取代的琥珀酰亚胺化合物。
• CATALYSTS AND METHODS FOR ENANTIOSELECIVE CONJUGATE ADDITION OF AMINES TO UNSATURATED ELECTROPHILES
  申请人：Northwestern University

  公开号：US20210002221A1

  公开（公告）日：2021-01-07

  Disclosed are complexes and methods of using the complexes as catalysts for addition of amines to unsaturated electrophiles, as well as novel compounds produced by the disclosed complexes and methods. The disclosed methods may utilize the disclosed complexes as catalysts for adding unprotected primary amines and secondary amines to unsaturated electrophiles in an enantioselective manner to produce novel compounds which may include amino substituted succinimide compounds.