Heptanoylcarnitine

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Heptanoylcarnitine
• 英文别名: 3-heptanoyloxy-4-(trimethylazaniumyl)butanoate
• 化学式: C14H27NO4
• 分子量: 273.37
• InChiKey: VDPCTFWULDLKHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  66.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• NEW BIOMARKERS FOR ASSESSING KIDNEY DISEASES
  申请人：BIOCRATES Life Sciences AG

  公开号：EP2438441B1

  公开（公告）日：2014-05-21
• TRIHEPTANOIN DIET FOR ADULT POLYGLUCOSAN BODY DISEASE (APBD) TREATMENT
  申请人：Baylor Research Institute

  公开号：EP2579867A1

  公开（公告）日：2013-04-17
• LIPID, PROTEIN, AND METABOLITE MARKERS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER
  申请人：Berg LLC

  公开号：EP3490677A1

  公开（公告）日：2019-06-05
• BIOMARKERS FOR ASSESSING KIDNEY DISEASES
  申请人：BIOCRATES LIFE SCIENCES AG

  公开号：US20170016908A1

  公开（公告）日：2017-01-19

  The present invention relates to a metabolic biomarker set for assessing kidney disease comprising at least two amino acids, at least two acylcarnitines and at least two biogenic amines. Moreover, the present invention relates to a method for assessing kidney disease in a mammalian subject which comprises obtaining a biological sample, preferably blood and/or urine, from the subject and measuring in the biological sample the amount of at least two amino acids, of at least two acylcarnitines and of at least two biogenic amines, as well as to a kit adapted to carry out the method. By employing the specific biomarkers and the method according to the present invention it becomes possible to more properly and reliably assess kidney disease.
• ASPARAGINASE THERAPEUTIC METHODS
  申请人：The Broad Institute, Inc.

  公开号：US20210401953A1

  公开（公告）日：2021-12-30

  Provided herein, in some embodiments, are methods for detecting a level of asparaginase (ASNS) in a sample obtained from a subject having or at risk for stomach cancer or liver cancer, and methods of treating the subject.