The present invention covers substituted 3-Phenylquinazolin-4(3H)-one compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of various inflammatory and fibrotic diseases of the respiratory tract and of the lungs as well as lung cancer, as a sole agent or in combination with other active ingredients.
本发明涵盖了通式(I)所述和定义的取代3-苯基
喹唑啉-4(3H)-酮化合物,制备该化合物的方法,用于制备该化合物的有用中间体化合物,包含该化合物的药物组合物和组合物,以及利用该化合物制造用于治疗或预防疾病的药物组合物的用途,特别是用于治疗和/或预防呼吸道和肺部的各种炎症性和纤维化疾病以及肺癌,作为唯一药剂或与其他活性成分组合使用。