1-(4-(4-氟苯氧基)-2-氯苯基)乙酮 | 1021187-74-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1-(4-(4-氟苯氧基)-2-氯苯基)乙酮
• 英文名称: 1-(4-(4-fluorophenoxy)-2-chlorophenyl)ethanone
• 英文别名: 1-[2-Chloro-4-(4-fluorophenoxy)phenyl]ethan-1-one；1-[2-chloro-4-(4-fluorophenoxy)phenyl]ethanone
• CAS: 1021187-74-5
• 化学式: C₁₄H₁₀ClFO₂
• mdl: MFCD20557802
• 分子量: 264.684
• InChiKey: NRHFUAPESWFWDH-UHFFFAOYSA-N

物化性质

• 沸点：
  339.6±42.0 °C(Predicted)
• 密度：
  1.274±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.071
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-(4-(4-氟苯氧基)-2-氯苯基)乙酮 在 溴 作用下， 以 乙醚 为溶剂， 以90.1%的产率得到2-bromo-1-(2-chloro-4-(4-fluorophenoxy)phenyl)ethanone
  参考文献：
  名称：

  Synthesis and Fungicidal Evaluation of 2-Arylphenyl Ether-3-(1H-1,2,4-triazol-1-yl)propan-2-ol Derivatives

  摘要：

  A series of novel 2-arylphenyl ether-3-(1H-1,2,4-triazol-1-yl)propan-2-ol derivatives were designed and synthesized as candidate fungicides. The new compounds were identified by H-1 NMR spectroscopy and element analysis. Their antifungal activities were evaluated. They exhibited excellent antifungal activities against five common pathogens in comparison with the commercial fungicides tebuconazole and difenoconazole. The antifungal activities of three new triazole alcohol compounds were compared with those of tebuconazole and difenoconazole at a concentration of 1 mu g/mL.

  DOI：

  10.1021/jf900222s
• 作为产物：
  描述：

  4-氟苯酚 、 2-氯-4-氟苯乙酮 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 1.5h， 生成 1-(4-(4-氟苯氧基)-2-氯苯基)乙酮
  参考文献：
  名称：

  AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGRICULTURAL OR HORTICULTURAL CHEMICAL AGENT, AND PROTECTIVE AGENT FOR INDUSTRIAL MATERIAL

  摘要：

  提供一种植物病害控制剂，对人类和动物毒性低，具有出色的操作安全性，在各种植物病害上显示出优秀的控制效果，并对植物病原菌具有高抗生素作用。 由以下一般式（I）表示的化合物，或其N-氧化物或农药可接受的盐。

  公开号：

  US20200288714A1

文献信息

• CN116746578
  申请人：——

  公开号：——

  公开（公告）日：——
• AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGRICULTURAL OR HORTICULTURAL CHEMICAL AGENT, AND PROTECTIVE AGENT FOR INDUSTRIAL MATERIAL
  申请人：Kureha Corporation

  公开号：US20200288714A1

  公开（公告）日：2020-09-17

  It is provided a plant disease controlling agent having low toxicity to human and animals and excellent handling safety, and showing excellent controlling effects on various plant diseases and high antibiotic action to plant disease germs. A compound represented by the following the general formula (I), or an N-oxide or agrochemically acceptable salt thereof.

  提供一种植物病害控制剂，对人类和动物毒性低，具有出色的操作安全性，在各种植物病害上显示出优秀的控制效果，并对植物病原菌具有高抗生素作用。 由以下一般式（I）表示的化合物，或其N-氧化物或农药可接受的盐。
• Synthesis and Fungicidal Evaluation of 2-Arylphenyl Ether-3-(1<i>H</i>-1,2,4-triazol-1-yl)propan-2-ol Derivatives
  作者：Guan-Ping Yu、Liang-Zhong Xu、Xu Yi、Wen-Zhao Bi、Qi Zhu、Zhi-Wei Zhai

  DOI：10.1021/jf900222s

  日期：2009.6.10

  A series of novel 2-arylphenyl ether-3-(1H-1,2,4-triazol-1-yl)propan-2-ol derivatives were designed and synthesized as candidate fungicides. The new compounds were identified by H-1 NMR spectroscopy and element analysis. Their antifungal activities were evaluated. They exhibited excellent antifungal activities against five common pathogens in comparison with the commercial fungicides tebuconazole and difenoconazole. The antifungal activities of three new triazole alcohol compounds were compared with those of tebuconazole and difenoconazole at a concentration of 1 mu g/mL.