果糖-天冬氨酰胺 | 34393-27-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 果糖-天冬氨酰胺
• 中文别名: 果糖-天冬氨酰胺
• 英文名称: Fructose-asparagine
• 英文别名: (2R)-4-amino-4-oxo-2-[[(3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylamino]butanoic acid
• CAS: 34393-27-6
• 化学式: C₁₀H₁₈N₂O₈
• 分子量: 294.26
• InChiKey: AOBQWGHMIKNEHI-CWOUCCJVSA-N

物化性质

• 熔点：
  >190°C (dec.)
• 溶解度：
  可微溶于水

计算性质

• 辛醇/水分配系数(LogP)：
  -6.4
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  183
• 氢给体数：
  7
• 氢受体数：
  9

文献信息

• Methods for the identification, characterization, and use of inhibitors of the fructose-asparagine utilization pathway
  申请人：SABER BIOTICS, LLC

  公开号：US10752933B2

  公开（公告）日：2020-08-25

  The present embodiments provide for media useful for selection and enrichment of Salmonella species. In a particular embodiment, the medium is a minimal medium that includes fructose-asparagine as the sole nutrient source. The fructose-asparagine utilization pathway, particularly FraB, provides a highly selective drug target for inhibiting Salmonella enterica.

  本实施方案提供了用于选择和富集沙门氏菌的培养基。在一个特定的实施方案中，培养基是一种包含果糖-天冬酰胺作为唯一营养源的最小培养基。果糖-天冬酰胺利用途径，特别是 FraB，为抑制肠炎沙门氏菌提供了一个高选择性的药物靶点。
• SELECTIVE MEDIA AND USES THEREOF
  申请人：SABER BIOTICS, LLC

  公开号：US20180187238A1

  公开（公告）日：2018-07-05

  The present embodiments provide for media useful for selection and enrichment of Salmonella species. In a particular embodiment, the medium is a minimal medium that includes fructose-asparagine as the sole nutrient source. The fructose-asparagine utilization pathway, particularly FraB, provides a highly selective drug target for inhibiting Salmonella enterica.
• [EN] SELECTIVE MEDIA AND USES THEREOF<br/>[FR] MILIEUX SÉLECTIFS ET LEURS UTILISATIONS
  申请人：SABER BIOTICS LLC

  公开号：WO2016210436A1

  公开（公告）日：2016-12-29

  The present embodiments provide for media useful for selection and enrichment of Salmonella species. In a particular embodiment, the medium is a minimal medium that includes fructose-asparagine as the sole nutrient source. The fructose-asparagine utilization pathway, particularly FraB, provides a highly selective drug target for inhibiting Salmonella enterica.