1-[2-(磺基氧基)乙基]-吡啶鎓内盐 | 6142-30-9

• 物质功能分类: 医药中间体 - 吡啶类化合物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 1-[2-(磺基氧基)乙基]-吡啶鎓内盐
• 英文名称: Pyridinium-β-sulfatoaethylbetain
• 英文别名: 2-(1-Proto-1-pyridyl)-1-aethansulfonat；1-<2-Sulfooxy-ethyl>-pyridinium-betain；1-[2-(sulfonatooxy)ethyl]pyridinium；1-(2-(Sulphonatooxy)ethyl)pyridinium；2-pyridin-1-ium-1-ylethyl sulfate
• CAS: 6142-30-9
• 化学式: C₇H₉NO₄S
• 分子量: 203.219
• InChiKey: VUOQDVJCGIRTJN-UHFFFAOYSA-N

物化性质

• 熔点：
  203 °C

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  78.7
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 海关编码：
  2933399090

反应信息

• 作为产物：
  描述：

  吡啶 、 环氧乙烷 生成 1-[2-(磺基氧基)乙基]-吡啶鎓内盐
  参考文献：
  名称：

  BRAUN, GEROLD;TSCHANG, CHUNG-JI;VAMVAKARIS, CHRISTOS;GLASER, KLAUS

  摘要：

  DOI：

文献信息

• Solvent systems for pharmaceutical agents
  申请人：——

  公开号：US20020102280A1

  公开（公告）日：2002-08-01

  The invention provides compositions, solvent systems, and methods for solubilizing compounds which are otherwise difficult to solubilize. The invention involves the use of a structured fluid (e.g. a liquid crystalline phase, an L1 phase, an L2 phase, an L3 phase, an emulsion, or a microemulsion), comprising a polar solvent, a lipid or a surfactant, and an essential oil or a dissolution/solubilization agent.

  这项发明提供了用于溶解那些通常难以溶解的化合物的组合物、溶剂系统和方法。该发明涉及使用结构化流体（例如液晶相、L1相、L2相、L3相、乳化液或微乳化液），其中包括极性溶剂、脂质或表面活性剂以及精油或溶解/溶解剂。
• Particles with improved solubilization capacity
  申请人：——

  公开号：US20030022242A1

  公开（公告）日：2003-01-30

  A particle is disclosed that comprises a first volume of hydrophobe-rich material with tunable dissolution and solubilization characteristics and a distinct second volume of nanostructured nonlamellar liquid crystalline material, said second volume containing said first domain and being capable of being in equilibrium with said first volume. Preferably, the nanostructured nonlamellar liquid crystalline material is capable of being in equilibrium with a polar solvent or a water-immiscible solvent or both.

  揭示了一种颗粒，包括具有可调溶解和溶解特性的第一体积的疏水基质材料和独特的第二体积的纳米结构非层状液晶材料，所述第二体积包含所述第一领域，并能够与所述第一体积处于平衡状态。优选，所述纳米结构非层状液晶材料能够与极性溶剂或水不相溶溶剂或两者同时处于平衡状态。
• COATED PARTICLES, METHODS OF MAKING AND USING
  申请人：——

  公开号：US20040201117A1

  公开（公告）日：2004-10-14

  A particle coated with a nonlamellar material such as a nonlamellar crystalline material, a nonlamellar amorphous material, or a nonlamellar semi-crystalline material includes an internal matrix core having at least one a nanostructured liquid phase, or at least on nanostructured liquid crystalline phase or a combination of the two is used for the delivery of active agents such as pharmaceuticals, nutrients, pesticides, etc. The coated particle can be fabricated by a variety of different techniques where the exterior coating is a nonlamellar material such as a nonlamellar crystalline material, a nonlamellar amorphous material, or a nonlamellar semi-crystalline material

  涂覆有非层状材料（如非层状晶体材料、非层状非晶态材料或非层状半晶态材料）的粒子，包括具有至少一个纳米结构液相或至少一个纳米结构液晶相或两者的组合的内部基质核心，用于传递活性剂，如药物、营养素、杀虫剂等。涂覆的粒子可以通过各种不同的技术制造，其中外部涂层是非层状材料，如非层状晶体材料、非层状非晶态材料或非层状半晶态材料。
• Coated particles, methods of making and using
  申请人：——

  公开号：US20030108743A1

  公开（公告）日：2003-06-12

  A particle coated with a nonlamellar material such as a nonlamellar crystalline material, a nonlamellar amorphous material, or a nonlamellar semi-crystalline material includes an internal matrix core having at least one a nanostructured liquid phase, or at least on nanostructured liquid crystalline phase or a combination of the two is used for the delivery of active agents such as pharmaceuticals, nutrients, pesticides, etc. The coated particle can be fabricated by a variety of different techniques where the exterior coating is a nonlamellar material such as a nonlamellar crystalline material, a nonlamellar amorphous material, or a nonlamellar semi-crystalline material

  涂覆有非层状材料的颗粒，例如非层状晶体材料、非层状非晶材料或非层状半晶材料，包括至少一个纳米结构液相的内部基质核心，或至少一个纳米结构液晶相或两者的组合，用于传递活性物质，如药物、营养素、杀虫剂等。涂覆的颗粒可以通过各种不同的技术制造，其中外部涂层是非层状材料，例如非层状晶体材料、非层状非晶材料或非层状半晶材料。
• Nanoporous particle with a retained target
  申请人：——

  公开号：US20030232340A1

  公开（公告）日：2003-12-18

  Porous nanostructured materials, such as porous nanostructured liquid and liquid crystalline particles or materials, incorporate a target substantially within the material which selectively binds a chemical of interest which can diffusion within the porous nanostructured material and be bound by the target. The porous nanostructured materials can be dispersed as particles in a medium in which said chemical of interest is located with low turbidity. Markers which detect binding of said chemical of interest can be maintained in the medium separate and apart from the target, and any active compound (e.g., an enzyme) associated therewith by the porous nanostructured material, such that detectable changes in the marker only result when the active compounds diffuse out of the porous nanostructured materials after the chemical of interest binds to the target.

  多孔纳米结构材料，如多孔纳米结构液体和液体结晶颗粒或材料，在材料内部基本包含一个靶标，该靶标可选择性地结合感兴趣的化学物质，该化学物质可在多孔纳米结构材料内部扩散并被靶标结合。多孔纳米结构材料可作为微粒分散在低浊度的介质中，所述化学物质就在该介质中。多孔纳米结构材料可将检测所述相关化学物质结合情况的标记物保持在介质中，与目标物和与之相关的任何活性化合物（如酶）分开，只有当相关化学物质与目标物结合后，活性化合物从多孔纳米结构材料中扩散出来时，标记物才会发生可检测的变化。