镧柠檬酸盐 | 3002-52-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 镧柠檬酸盐
• 英文名称: 2-Hydroxypropane-1,2,3-tricarboxylic acid;lanthanum
• 英文别名: 2-hydroxypropane-1,2,3-tricarboxylic acid;lanthanum
• CAS: 3002-52-6
• 化学式: C6H8LaO7
• 分子量: 331.03
• InChiKey: KDEIPINVCPEDHK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.25
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  132
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• [EN] TREATMENT OF INFECTIONS<br/>[FR] TRAITEMENT D'INFECTIONS
  申请人：ASCENDIS PHARMA AS

  公开号：WO2020064844A1

  公开（公告）日：2020-04-02

  The present invention relates among other aspects to a conjugate or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising said conjugate or its pharmaceutically acceptable salt for use in a method of preventing or treating an infection, wherein said conjugate is water-insoluble and comprises a polymeric moiety -Z to which a plurality of moieties -L2-X0D-L1-D are covalently conjugated, wherein each -D is independently an antibiotic moiety; each -L1- is independently a linker moiety to which -D is covalently and reversibly conjugated; each -X0D- is independently absent or a linkage and each -L2- is independently either a chemical bond or a spacer moiety.

  本发明涉及一种共轭物或其药用可接受的盐，或包含所述共轭物或其药用可接受的盐的药物组合物，用于预防或治疗感染的方法，其中所述共轭物不溶于水，包括一个聚合物基团-Z，其中多个基团-L2-X0D-L1-D以共价结合方式共轭，其中每个-D独立地是抗生素基团；每个-L1-独立地是连接基团，与-D以共价和可逆方式结合；每个-X0D-独立地不存在或是一个连接，每个-L2-独立地是化学键或间隔基团。
• Assay for lanthanum hydroxycarbonate
  申请人：Hallenbeck Donald

  公开号：US20070259052A1

  公开（公告）日：2007-11-08

  An assay for analytically determining the amount of an impurity in a solid sample is provided. This X-ray diffraction method preferably uses the Rietveld refinement.

  提供了一种用于分析确定固体样品中杂质量的测定方法。该X射线衍射方法首选使用Rietveld精修。
• Assay for lanthanum hydroxy carbonate
  申请人：Shire International Licensing B.V.

  公开号：EP1852695A1

  公开（公告）日：2007-11-07

  An assay for analytically determining the amount of an impurity in a solid sample is provided. This X-ray diffraction method preferably uses the Rietveld refinement.

  提供了一种分析测定固体样品中杂质含量的方法。这种 X 射线衍射方法最好使用里特维尔德精炼法。
• Stable color-protecting hair treatment agent comprising lanthanide salt
  申请人：Henkel AG & Co. KGaA

  公开号：US10857081B2

  公开（公告）日：2020-12-08

  A hair treatment agent for reducing and/or preventing the bleeding out and/or fading of artificially produced hair colors is provided herein. The hair treatment agent has a pH value in the range of from about 4 to about 5. The hair treatment agent includes, relative to the total amount of the hair treatment agent, from about 0.01 to about 10% by weight of a lanthanum and/or lanthanide salt, at least one anionic surfactant selected from the group of alkyl (ether) sulfates, sulfosuccinates, ether carboxylic acids, N-acylamino acids having 8 to 24 C atoms in the acyl group, (acyl) isethionates having 8 to 24 C atoms in the acyl group, and mixtures of these surfactants, and from about 0.01 to about 10% by weight of an organic acid selected from the group of maleic acid, lactic acid, acetic acid, propanoic acid, amino acids, and mixtures thereof.

  本文提供了一种头发处理剂，用于减少和/或防止人工制造的发色渗出和/或褪色。相对于头发处理剂的总量，头发处理剂包括约 0.01至约10%（按重量计）的镧和/或镧化盐，至少一种选自烷基（醚）硫酸盐、磺基琥珀酸盐、醚羧酸、酰基中具有8至24个C原子的N-酰基氨基酸、酰基中具有8至24个C原子的（酰基）异硫酸盐和这些表面活性剂的混合物的阴离子表面活性剂，以及约0.01至约10%（重量）的选自马来酸、乳酸、乙酸、丙酸、氨基酸及其混合物的有机酸。
• PROPHYLACTIC TREATMENT OF ALLERGIC CONTACT DERMATITIS
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：EP0802731A1

  公开（公告）日：1997-10-29