1-吡啶-4-基苯并三唑 | 66571-30-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并三唑类
• 中文名称: 1-吡啶-4-基苯并三唑
• 英文名称: 1-(4-Pyridyl)benzotriazole
• 英文别名: 1-(Pyridin-4-yl)-1h-benzotriazole；1-pyridin-4-ylbenzotriazole
• CAS: 66571-30-0
• 化学式: C₁₁H₈N₄
• 分子量: 196.211
• InChiKey: VYPSCVFMEKLKGG-UHFFFAOYSA-N

物化性质

• 熔点：
  113.5 °C
• 沸点：
  399.5±44.0 °C(Predicted)
• 密度：
  1.31±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  43.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-吡啶-4-基苯并三唑 在 吡啶 、 焦磷酸 作用下， 反应 0.5h， 生成 1-Pyrido[4,3-b]indol-5-yl-ethanone
  参考文献：
  名称：

  Synthesis and DNA Binding Properties of γ-Carbolinium Derivatives and Benzologues

  摘要：

  The 5H-pyrido[4,3-b]indole, 11H-indolo[3,2-c]quinoline, 5H-benzo[f]pyrido[4,3-b]indole, and 13H-benz[5,6]indolo[3,2-c]quinoline heteroaromatic nuclei have been synthesized by the Graebe-Ullmann method by classical heating or under microwave irradiation. These tri-, tetra-, and pentacyclic compounds were transformed into the corresponding cationic derivatives by N-alkylation, and the DNA-binding properties of the resulting cationic systems were examined using UV-vis spectroscopy, viscometric determinations, and molecular modeling techniques. The tetracyclic cations were transformed into his-salts by means of a diethyl bispiperidine rigid chain and a more flexible polyamide linker, but the low solubility of these bis-salts made the study of their bisintercalating properties difficult.

  DOI：

  10.1021/jo960266h
• 作为产物：
  描述：

  4'-Benzotriazol-1-yl-2,6-dimethyl-4'H-[1,1']bipyridinyl-4-one 在 过氧化苯甲酰 作用下， 以 氯仿 为溶剂， 反应 8.0h， 以51%的产率得到1-吡啶-4-基苯并三唑
  参考文献：
  名称：

  N–N连锁杂环的合成应用。第9部分。在N-（2,6-二甲基-4-氧代吡啶-1-基）吡啶盐上通过硝基烷基和偶氮基阴离子的区域专一性攻击制备α-（4-吡啶基）硝基烷和N-（4-吡啶基）唑

  摘要：

  硝基烷烃和吡咯的钠盐与N-（2,6-二甲基-4-氧杂吡啶-1-基）吡啶鎓盐（1）–（3）反应生成区域特异性的1,4-二氢吡啶（12）–（14） ，（15）和（16）高产。二氢吡啶的光解作用可以中等至良好的产率得到α-（4-吡啶基）硝基烷烃（7）-（9）和N-（4-吡啶基）唑。某些偶氮基二氢吡啶在光解时会还原为母体吡咯；这似乎是位阻效应。

  DOI：

  10.1039/p19810000588

文献信息

• One-pot Graebe-Ullmann synthesis of γ-carbolines under microwave irradiation
  作者：Andrés Molina、Juan J. Vaquero、José L. García-Navio、Julio Alvarez-Builla

  DOI：10.1016/s0040-4039(00)77653-2

  日期：1993.4

  One-pot efficient and simple synthesis of γ-carboline derivatives by the Graebe-Ullmann method was conducted in a commercial microwave oven in a few minutes at a low energy level and using erlenmeyer as adequate reaction vessels. Yields are similar to those obtained by conventional heating.

  通过Graebe-Ullmann方法一锅高效，简单地合成γ-咔啉衍生物是在商用微波炉中以低能级在几分钟内以锥形瓶作为适当的反应容器进行的。产率类似于通过常规加热获得的产率。
• NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：EP3279997A1

  公开（公告）日：2018-02-07

  The purpose of the present invention is to provide a nonaqueous electrolyte that contains acetonitrile having an excellent balance between viscosity and the dielectric constant and a fluorine-containing inorganic lithium salt, wherein the generation of complex cations comprising a transition metal and acetonitrile is suppressed, excellent load characteristics are exhibited, and increases in internal resistance upon repeated charge/discharge cycles are suppressed; a further purpose of the present invention is to provide a nonaqueous secondary battery. The present invention relates to a nonaqueous electrolyte which contains: a nonaqueous solvent comprising acetonitrile; a fluorine-containing inorganic lithium salt; and a specific nitrogenous cyclic compound typified by benzotriazole.

  本发明的目的是提供一种非水电解液，该电解液含有在粘度和介电常数之间具有极佳平衡的乙腈和含氟无机锂盐，其中包含过渡金属和乙腈的复合阳离子的生成受到抑制，显示出极佳的负载特性，并且在重复充放电循环中内阻的增加受到抑制；本发明的另一个目的是提供一种非水二次电池。本发明涉及一种非水电解液，其中包含：由乙腈组成的非水溶剂；含氟无机锂盐；以及以苯并三唑为典型代表的特定含氮环状化合物。
• Nonaqueous electrolyte and nonaqueous secondary battery
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：US10756394B2

  公开（公告）日：2020-08-25

  The purpose of the present invention is to provide a nonaqueous electrolyte that contains acetonitrile having an excellent balance between viscosity and the dielectric constant and a fluorine-containing inorganic lithium salt, wherein the generation of complex cations comprising a transition metal and acetonitrile is suppressed, excellent load characteristics are exhibited, and increases in internal resistance upon repeated charge/discharge cycles are suppressed; a further purpose of the present invention is to provide a nonaqueous secondary battery. The present invention relates to a nonaqueous electrolyte which contains: a nonaqueous solvent comprising acetonitrile; a fluorine-containing inorganic lithium salt; and a specific nitrogenous cyclic compound typified by benzotriazole.

  本发明的目的是提供一种非水电解液，该电解液含有在粘度和介电常数之间具有极佳平衡的乙腈和含氟无机锂盐，其中包含过渡金属和乙腈的复合阳离子的生成受到抑制，显示出极佳的负载特性，并且在重复充放电循环中内阻的增加受到抑制；本发明的另一个目的是提供一种非水二次电池。本发明涉及一种非水电解液，其中包含：由乙腈组成的非水溶剂；含氟无机锂盐；以及以苯并三唑为典型代表的特定含氮环状化合物。
• Fluorescence Studies with Tryptophan Analogs: Excited State Interactions Involving the Side Chain Amino Group
  作者：Maurice R. Eftink、Jiwei Jia、Dana Hu、Camillo A. Ghiron

  DOI：10.1021/j100015a064

  日期：1995.4

  The fluorescence of a large set of tryptophan analogues, including several that are conformationally constrained, was studied. The constrained analogues include tetrahydrocarboline-3-carboxylic acid and 3-amino-3-carboxytetrahydrocarbazole. Steady state and time-resolved fluorescence measurements were made as a function of pH. The fluorescence quantum yields of the constrained analogues are higher than those for the unconstrained counterparts. The emission intensity of the constrained analogues, as well as 4-methyltryptophan, decreases with deprotonation of the side chain alpha-ammonium group; this is in contrast to the increase in fluorescence of tryptophan with deprotonation of this group. These results are consistent with the existence of excited state proton transfer to carbon 4 of the indole ring as a quenching mechanism, which is sterically prohibited in the constrained analogues and 4-methyltryptophan. From quantum yield and lifetime data (most decays are nonexponential), the effective rate constant for nonradiative depopulation of the excited state was calculated. For tryptophan analogues having two side chain functional groups, there is a synergistic effect; the presence of two side chain groups causes more quenching than expected from the sum of the individual contributions. For analogues having ana-ammonium group, this synergism appears to be correlated with an induced change in the pK(alpha) of this group. Deprotonation of this cl-ammonium group also causes a red shift in the emission of these compounds; this appears to be due to electrostatic repulsion between the alpha-NH3+ group and the excited indole dipole.
• CCLXXXVII.—5-Carboline and some derivatives
  作者：Robert Robinson、Sidney Thornley

  DOI：10.1039/ct9242502169

  日期：——