1-羟基-2-乙酰氧基庚烷 | 81947-74-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 1-羟基-2-乙酰氧基庚烷
• 英文名称: 1-hydroxy-2-acetoxyheptane
• 英文别名: 2-acetoxyheptan-1-ol；1-Hydroxyheptan-2-yl acetate
• CAS: 81947-74-2
• 化学式: C₉H₁₈O₃
• 分子量: 174.24
• InChiKey: AGZWFTYNPLMZMX-UHFFFAOYSA-N

物化性质

• 沸点：
  264.5±13.0 °C(Predicted)
• 密度：
  0.976±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-庚烯 生成 1-羟基-2-乙酰氧基庚烷
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Sodium perborate oxidations of cyclic and acyclic alkenes to oxiranes or vicinal acetoxy alcohols
  作者：Gaoyang Xie、Linxiao Xu、Jun Hu、Shining Ma、Wei Hou、Fenggang Tao

  DOI：10.1016/0040-4039(88)85059-7

  日期：1988.1

  Under different reaction conditions, sodium perborate/acetic anhydride oxidizes alkenes into oxiranes or vicinal acetoxy alcohols in good yields.

  在不同的反应条件下，过硼酸钠/乙酸酐可以高收率将烯烃氧化为环氧乙烷或邻位乙酰氧基醇。
• Synthesis of higher epoxides by the joint catalytic oxidation of aldehydes and olefins
  作者：M. G. Vinogradov、I. P. Kovalev、G. I. Nikishin

  DOI：10.1007/bf00963242

  日期：1985.10
• Kinetic resolution of 2-acylated-1,2-diols by lipase-catalyzed enantiomer selective acylation
  作者：Gabriella Egri、Eszter Baitz-Gács、László Poppe

  DOI：10.1016/0957-4166(96)00161-9

  日期：1996.5

  Enantiomer selectivity of lipase catalyzed acylation of 2-acylated 1,2-diols was studied. First, acylation of 2-acetoxyheptan-1-ol rac-3b with vinyl acetate was investigated by varying the enzyme and the solvent, showing the highest enantiomer selectivity by using lipase from Pseudomonas fluorescens (PfL) in hexane-vinyl acetate (VA). We have found varying or even reversed enantiomer selectivity for different secondary acyl moieties in 2-acyloxyheptan-1-ols rac-3bA-F. Next, all six possible types of enantiomer selective biotransformations (hydrolysis of diacetate and the two kinds of monoacetetes; acylation of diol and the two kinds of monoacetates) were compared on two model diols rac-4b,d. Among the transformations investigated, acetylation of secondary monoacetates rac-3b,d showed the highest enantiomer selectivity. Finally, PfL catalyzed acetylations of several 2-acetylated 1,2-diols rac-3a-g were investigated under our optimum conditions. Copyright (C) 1996 Elsevier Science Ltd
• ——
  作者：VOJTKO J.、 HRUSOVSKY CIHOVA, M.

  DOI：——

  日期：——
• ——
  作者：VOJTKO J.、 CIHOVA M.、 HRUSOVSKY M.

  DOI：——

  日期：——