1-芘基beta-D-苏式-吡喃己酮糖苷酸 | 154717-05-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 中文名称: 1-芘基beta-D-苏式-吡喃己酮糖苷酸
• 中文别名: (1-芘基)-Β-D-葡糖苷酸
• 英文名称: 1-Hydroxypyrene beta-D-Glucuronide
• 英文别名: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-pyren-1-yloxyoxane-2-carboxylic acid
• CAS: 154717-05-2
• 化学式: C₂₂H₁₈O₇
• 分子量: 394.4
• InChiKey: BUCREAQPYGLZLI-SXFAUFNYSA-N

物化性质

• 熔点：
  188°C (dec.)
• 沸点：
  719.3±60.0 °C(Predicted)
• 密度：
  1.624±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于DMSO（轻微）、甲醇（轻微、加热）

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  116
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• Detection of biological molecules by differential partitioning of enzyme substrates and products
  申请人：Brown R. Stephen

  公开号：US20090117600A1

  公开（公告）日：2009-05-07

  This invention relates to a method and apparatus for detecting a biological molecule associated with enzyme activity in a sample. The invention is applicable to detecting a microorganism associated with an enzyme in a sample such as water, food, soil, or a biological sample. According to a preferred embodiment of the method of the invention, a sample containing an enzyme of interest or a microorganism associated with the enzyme is combined with a suitable substrate, and a fluorescent product of the enzyme-substrate reaction is selectively detected. The fluorescent product is detected with a partitioning element or optical probe/partitioning element of the invention. In one embodiment the partitioning element provides for partitioning of only the fluorescent product molecule into the probe. The invention also provides an automated system for monitoring for biological contamination of water or other samples.
• DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS
  申请人：QUEEN'S UNIVERSITY AT KINGSTON

  公开号：US20130217041A1

  公开（公告）日：2013-08-22

  This invention relates to a method and apparatus for detecting a biological molecule associated with enzyme activity in a sample. The invention is applicable to detecting a microorganism associated with an enzyme in a sample such as water, food, soil, or a biological sample. According to a preferred embodiment of the method of the invention, a sample containing an enzyme of interest or a microorganism associated with the enzyme is combined with a suitable substrate, and a fluorescent product of the enzyme-substrate reaction is selectively detected. The fluorescent product is detected with a partitioning element or optical probe/partitioning element of the invention. In one embodiment the partitioning element provides for partitioning of only the fluorescent product molecule into the probe. The invention also provides an automated system for monitoring for biological contamination of water or other samples.
• US7402426B2
  申请人：——

  公开号：US7402426B2

  公开（公告）日：2008-07-22
• US8377686B2
  申请人：——

  公开号：US8377686B2

  公开（公告）日：2013-02-19
• US8632966B2
  申请人：——

  公开号：US8632966B2

  公开（公告）日：2014-01-21