1-苯基-1,2-丁二醇 | 22607-13-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1-苯基-1,2-丁二醇
• 英文名称: 1-phenylbutane-1,2-diol
• 英文别名: optically inactive 1-phenyl-butanediol-(1.2)；Opt.-inakt. 1-Phenyl-butandiol-(1.2)；α-Aethyl-α'-phenyl-aethylenglykol；(α.β-Dioxy-butyl)-benzol；1-Phenyl-butan-1,2-diol；1-Phenyl-1,2-butanediol
• CAS: 22607-13-2
• 化学式: C₁₀H₁₄O₂
• 分子量: 166.22
• InChiKey: WFSOUGZEVPHHSM-UHFFFAOYSA-N

物化性质

• 沸点：
  140-150 °C(Press: 10 Torr)
• 密度：
  1.097±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2906299090

反应信息

• 作为反应物：
  描述：

  1-苯基-1,2-丁二醇 在 硫酸 作用下， 生成 1-苯基-2-丁酮
  参考文献：
  名称：

  Levy; Gombinska, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1929, vol. 188, p. 713

  摘要：

  DOI：
• 作为产物：
  描述：

  trans-2-Ethyl-3-phenyloxirane 在 硫酸 作用下， 以 四氢呋喃 、 水 为溶剂， 以95%的产率得到1-苯基-1,2-丁二醇
  参考文献：
  名称：

  从芳基烯烃的生物催化单步烯烃裂解：酶法等同于还原性臭氧化。

  摘要：

  DOI：

  10.1002/anie.200601574

文献信息

• Separation and Identification of Volatile Components in the Fermentation Broth of Trichoderma atroviride by Solid-Phase Extraction and Gas Chromatography--Mass Spectrometry
  作者：A. Keszler、E. Forgacs、L. Kotai、J. A. Vizcaino、E. Monte、I. Garcia-Acha

  DOI：10.1093/chromsci/38.10.421

  日期：2000.10.1

  A preseparated fermentation broth of Trichoderma atroviride strain 11 is analyzed by gas chromatography followed by mass-spectral detection using a Finnigan MAT GCQ apparatus. After preseparation in a C18 and a silica gel column, nineteen pyrone and dioxolane derivatives and two aliphatic esters are obtained, respectively. Among these, the four dioxolane derivatives have not been identified previously

  通过气相色谱分析随后分离的阿魏木霉菌株11的发酵肉汤，然后使用Finnigan MAT GCQ仪器进行质谱检测。在C18和硅胶柱中进行预分离后，分别获得十九个吡喃酮和二氧戊环衍生物以及两种脂族酯。其中，四种二氧戊环衍生物先前尚未鉴定。发现主要成分为5,5'-二甲基-2H-吡喃-2-on。用于确定保留时间和峰面积（以离子数测量）的相对标准偏差分别为0.1％和4.5％。
• Compositions for weight loss with improved taste
  申请人：Kanebo, Ltd.

  公开号：US20040076690A1

  公开（公告）日：2004-04-22

  The present invention relates to compositions comprising compounds that induce weight and fat loss and compounds that mask the bitter and harsh taste of the composition. The invention further relates to a food, beverage, dietary supplement, medical food, or pet food comprising compounds that induce weight loss and compounds that mask the bitter and harsh taste of the product. The invention is further related to methods of reducing or controlling weight by administering such compositions. Further provided are cosmetic sheets for topical administration of compositions for inducing weight and fat loss.

  本发明涉及包含诱导体重和脂肪减少化合物以及掩盖配方的苦味和刺激味的化合物的组合物。本发明还涉及包含诱导减重化合物和掩盖产品的苦味和刺激味的食品、饮料、膳食补充剂、医学食品或宠物食品。本发明还涉及通过给予这种组合物来减轻或控制体重的方法。此外，还提供用于诱导体重和脂肪减少的组合物的局部给药的化妆品片。
• Optically active or racemic aminal derivatives, process for preparing same and for converting same to alpha-hydroxyaldehydes
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0011417A1

  公开（公告）日：1980-05-28

  An optically active or racemic a-hydroxyaldehyde of formula wherein R, represents a C6-C14 aryl group, C1-C10 alkyl group, C1-C10 alkenyl group, C2-C10 alkynyl group, C2-C14 aralkyl group, or a group containing a functional group in the organic portion of said groups and R: represents a C1-C10 alkyl group, C1-C10 alkenyl group, C1-C10 alkynyl group, C7-C14 aralkyl group, C6-C14 aryl group or a group containing a functional group in the organic portion of these groups, which is an important intermediate for preparation of pharmaceuticals and agricultural chemicals and can be prepared by reacting an optically active or racemic compound of formula wherein A represents a C6-C14 aryl group or a C1-C4 alkyl or alkoxy group- or halogen-substituted C6-C14 aryl group and R is as defined above, with a Grignard reagent, and thereafter hydrolyzing the reaction product. The compound of formula (1) above can for example be prepared by reaction of an arylglyoxal with an optically active or racemic 2-iN-substituted aminomethyl)pyrroiidine or by reacting a Grignard reagent with an optically active or racemic. diazabicyclooctane derivative which itself can be prepared from a glyoxylate ester or glyoxylate ester hemiacetal and a 2(-N-substituted aminomethyl)pyrrolidine.

  式中具有光学活性或外消旋的 a-羟基醛 其中 R 代表 C6-C14 芳基、C1-C10 烷基、C1-C10 烯基、C2-C10 炔基、C2-C14 芳烷基或在上述基团的有机部分含有官能团的基团，R：代表 C1-C10 烷基、C1-C10 烯基、C1-C10 炔基、C7-C14 芳基、C6-C14 芳基或在这些基团的有机部分含有官能团的基团。 其中 A 代表 C6-C14 芳基或 C1-C4 烷基或烷氧基或卤素取代的 C6-C14 芳基，R 如上定义，与格氏试剂反应，然后水解反应产物。 例如，上述式（1）化合物可通过芳基乙二醛与光学活性的或外消旋的 2-(-N-取代氨甲基)吡咯烷反应制备，或通过格氏试剂与光学活性的或外消旋的二氮杂双环辛烷衍生物反应制备，二氮杂双环辛烷衍生物本身可由乙醛酸酯或乙醛酸酯半缩醛和 2-(-N-取代氨甲基)吡咯烷制备。
• Manufacturing method of optically-active 1,2-diols
  申请人：KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0317998A2

  公开（公告）日：1989-05-31

  A process of manufacturing optically active (S)-1,2-diols, wherein (R)-1,2-diols represented by the general formula [ I ] (where: R represents a substituted or unsubstituted alkyl group, alkenyl group, aryl group or aralkyl group) or a mixture of diols of the general formula [ I ] and (S)-1,2-diols represented by the general formula [ II ] (Where: R represents the same as above) having an opposite configuration to the general formula [ I ] is subjected to the action of a microorganism capable of selectively metabolizing the diols of the general formula [ I ] , or capable of converting the diols of the general formula [ I ] into the diols of the general formula [ II ] , or having the both capabilities, and the formed and accumulated (S)-1,2-diols of the general formula [ II ] is collected. According to the present invention, optically active (S)-1,2-diols can be produced commercially and advantageously.

  一种制造光学活性(S)-1,2-二醇的工艺，其中(R)-1,2-二醇由通式[ I ]代表 其中R代表取代或未取代的烷基、烯基、芳基或芳烷基）或通式[ I ]的二元醇与通式[ II ]的(S)-1,2-二元醇的混合物（其中：R代表与上述相同的基团 (其中，R 表示与通式[ I ]相反构型的二元醇（R 与上述相同），在能够选择性代谢通式[ I ]的二元醇，或能够将通式[ I ]的二元醇转化为通式[ II ]的二元醇，或同时具有这两种能力的微生物的作用下，收集所形成和积累的通式[ II ]的(S)-1,2-二元醇。根据本发明，光学活性 (S)-1,2-二醇可以以商业方式有利地生产。
• METHOD FOR PRODUCING BRANCHED AROMATIC POLYCARBONATE RESIN
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：EP2883899A1

  公开（公告）日：2015-06-17

  The present invention provides a method for producing a branched aromatic polycarbonate resin that is molecular weight-increased, which comprises subjecting an aromatic polycarbonate prepolymer and a linking agent comprising a trifunctional or more of an aliphatic polyol compound to transesterification reaction in the presence of a transesterification catalyst under a reduced pressure condition.

  本发明提供了一种生产分子量增加的支链芳香族聚碳酸酯树脂的方法，该方法包括在减压条件下，将芳香族聚碳酸酯预聚物和由三官能团或更多脂肪族多元醇化合物组成的连接剂在酯交换催化剂存在下进行酯交换反应。