10-羟基十八碳-11-烯酸 | 143288-76-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 10-羟基十八碳-11-烯酸
• 英文名称: 10-hydroxyoctadec-11-enoic acid
• 英文别名: 10-Hydroxyoctadec-11-enoic acid
• CAS: 143288-76-0
• 化学式: C₁₈H₃₄O₃
• 分子量: 298.466
• InChiKey: VALAUXDVLYFOEG-UHFFFAOYSA-N

物化性质

• 沸点：
  439.7±18.0 °C(Predicted)
• 密度：
  0.957±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  21
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  10-羟基十八碳-11-烯酸 、 N,O-双(三甲基硅烷基)三氟乙酰胺 在 吡啶 作用下， 反应 1.0h， 生成
  参考文献：
  名称：

  羟基羧酸和氧代羧酸三甲基甲硅烷基衍生物的 EI 质谱裂解过程中的氢和三甲基甲硅烷基转移。

  摘要：

  这篇论文描述了一些羟基羧酸和氧代羧酸三甲基甲硅烷基衍生物的电子电离质谱碎片，重点关注这些化合物的两个官能团之间相互作用导致的碎片离子的形成。这些相互作用导致在 [CH2=C(OTMS)2]+.、[CH2=CHC(OTMS)=OTMS]+、[M-31]+、[M-105]+ 和 [ M-RCHO]+。对于式 RCHOTMS(CH2)nCOOTMS 和 [RC(OTMS)=CH2]+.、[RC(=OTMS)CH=CH2]+ 和 [M-RC(=O)CH2] 的羟基羧酸三甲基甲硅烷基衍生物的情况]+ 在式 RC(=O)(CH2)nCOOTMS 的氧代羧酸三甲基甲硅烷基酯的情况下。其中一些碎片似乎具有足够的特异性，可用于表征这些化合物。

  DOI：

  10.1016/j.jasms.2007.10.014

文献信息

• INTESTINAL TRACT-PROTECTING AGENT CONTAINING HYDROXYLATED FATTY ACID
  申请人：Kyoto University

  公开号：EP2959897A1

  公开（公告）日：2015-12-30

  The present invention provides an intestinal tract-protecting agent, an agent for the prophylaxis or improvement of a disease caused by damage in intestinal tract barrier function, which contains hydroxylated fatty acid, particularly hydroxylated unsaturated fatty acid, having a hydroxyl group at the 10-position and/or the 12-position, which is an intermediate of the metabolism of unsaturated fatty acid by lactobacillus.

  本发明提供了一种肠道保护剂，一种用于预防或改善因肠道屏障功能受损而引起的疾病的药物，它含有羟基化脂肪酸，特别是羟基化不饱和脂肪酸，在 10 位和/或 12 位具有羟基，它是乳酸杆菌代谢不饱和脂肪酸的中间产物。
• ANTI-INFLAMMATORY AGENT CONTAINING RARE FATTY ACID
  申请人：Kyoto University

  公开号：EP3097910A1

  公开（公告）日：2016-11-30

  The present invention provides an anti-inflammatory agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the anti-inflammatory agent.

  本发明提供了一种含有稀有脂肪酸（如羟化脂肪酸、氧代脂肪酸等）的消炎剂，以及含有该消炎剂的食品、药品等。
• HYDROXYLATED FATTY ACID HOMOPOLYMER AND PRODUCTION METHOD THEREOF
  申请人：Kyoto University

  公开号：EP3677686A1

  公开（公告）日：2020-07-08

  The present invention provides a derivative of hydroxylated fatty acid which has a high content of hydroxylated fatty acid, and permits easy ingestion and easy handling, and a production method thereof. The present invention provides a method for producing a homopolymer of hydroxylated fatty acid, including polymerizing the hydroxylated fatty acid by using an enzyme. The homopolymer of hydroxylated fatty acid is stabilized. In addition, a novel, utilizable homopolymer of hydroxylated fatty acid obtained by this production method is also provided.

  本发明提供了一种羟基化脂肪酸的衍生物，其羟基化脂肪酸含量高，且易于摄取和处理，还提供了其生产方法。本发明提供了一种羟基化脂肪酸均聚物的生产方法，包括使用酶使羟基化脂肪酸聚合。羟化脂肪酸均聚物得到稳定。此外，本发明还提供了一种通过该生产方法获得的新型、可利用的羟基化脂肪酸均聚物。
• Method for producing oxo fatty acid and rare fatty acid
  申请人：KYOTO UNIVERSITY

  公开号：US10294501B2

  公开（公告）日：2019-05-21

  The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.

  本发明提供了一种氧化脂肪酸以及共轭脂肪酸、羟基化脂肪酸、部分饱和脂肪酸等稀有脂肪酸的生产方法，该方法使用了从植物乳杆菌（包括乳酸菌等）中提取的 4 种酶（脂肪酸-水解酶、羟基化脂肪酸-脱氢酶、氧化脂肪酸-异构酶、氧化脂肪酸-烯酮还原酶）。此外，本发明还提供了一种更高效的氧化脂肪酸等的生产方法，该方法部分结合使用了化学氧化反应。
• Golf ball resin composition and golf ball
  申请人：Dunlop Sports Co. Ltd.

  公开号：US10676602B2

  公开（公告）日：2020-06-09

  An object of the present invention is to provide a material from which a golf ball having excellent resilience and durability can be obtained. The present invention provides a golf ball resin composition containing: (A) at least one member selected from the group consisting of a polyamide, an ethylene-vinyl alcohol copolymer, a partially saponified product of an ethylene-vinyl acetate copolymer, and a polyvinyl alcohol, (B) at least one resin component selected from the group consisting of (b-1) a binary copolymer composed of an olefin and an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms, (b-2) a metal ion-neutralized product of a binary copolymer composed of an olefin and an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms, (b-3) a ternary copolymer composed of an olefin, an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms and an α,β-unsaturated carboxylic acid ester, and (b-4) a metal ion-neutralized product of a ternary copolymer composed of an olefin, an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms and an α,β-unsaturated carboxylic acid ester, and (C) a fatty acid metal salt having 18 or less carbon atoms.

  本发明的目的是提供一种材料，用它制成的高尔夫球具有极佳的回弹性和耐用性。本发明提供了一种高尔夫球树脂组合物，其中含有(A) 至少一种选自聚酰胺、乙烯-乙烯醇共聚物、乙烯-醋酸乙烯共聚物的部分皂化产物和聚乙烯醇的成员、(B) 至少一种选自以下组别的树脂组分 (b-1) 由烯烃和具有 3 至 8 个碳原子的 α、β-不饱和羧酸组成的二元共聚物， (b-2) 由烯烃和具有 3 至 8 个碳原子的 α、β-不饱和羧酸组成的二元共聚物的金属离子中和产物、(b-3) 由烯烃、具有 3 至 8 个碳原子的 α，β-不饱和羧酸和 α，β-不饱和羧酸酯组成的三元共聚物、(b-4) 由烯烃、具有 3 至 8 个碳原子的 α，β-不饱和羧酸和 α，β-不饱和羧酸酯组成的三元共聚物的金属离子中和产物，以及 (C) 具有 18 个或更少碳原子的脂肪酸金属盐。