12-羟基-N-十八烷基十八烷-1-酰胺 | 68155-52-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 12-羟基-N-十八烷基十八烷-1-酰胺
• 英文名称: 12-Hydroxy-N-octadecyloctadecanamide
• 英文别名: Octadecanamide, 12-hydroxy-N-octadecyl-
• CAS: 68155-52-2
• 化学式: C₃₆H₇₃NO₂
• 分子量: 551.981
• InChiKey: XJOOKFNMTRPLEG-UHFFFAOYSA-N

物化性质

• 熔点：
  106.9-107.3 °C
• 沸点：
  657.2±28.0 °C(Predicted)
• 密度：
  0.880±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  14.9
• 重原子数：
  39
• 可旋转键数：
  33
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] (R)-12-HYDROXYSTEARIC ACID HYDRAZIDES AS GELATORS AND SELF-STANDING GELS THEREOF<br/>[FR] HYDRAZIDES D'ACIDE (R)-12-HYDROXYSTÉARIQUE UTILISÉS COMME GÉLIFIANTS ET LEURS GELS AUTOPORTEURS
  申请人：UNIV GEORGETOWN

  公开号：WO2017117212A1

  公开（公告）日：2017-07-06

  (R)-12-hydroxystearic acid hydrazides as gelators and gels generated therefrom are provided. A series of (R)-12-hydroxystearic acid hydrazides produce gels that are self-standing and self-healing. The (R)-12-hydroxystearic acid hydrazides are capable of exhibiting gelling properties in a wide variety of solvents. The gels have demonstrated good potential for use in drug release.

  提供(R)-12-羟基硬脂酸腙作为凝胶剂及由此产生的凝胶。一系列(R)-12-羟基硬脂酸腙产生的凝胶具有自立和自修复性质。这些(R)-12-羟基硬脂酸腙能够在各种溶剂中展现凝胶特性。这些凝胶已经展示出在药物释放中的潜力。
• [EN] LOW MOLECULAR WEIGHT GELATORS FOR CRUDE OIL, PETROLEUM PRODUCT OR CHEMICAL SPILL CONTAINMENT<br/>[FR] GÉLIFIANTS DE FAIBLE POIDS MOLÉCULAIRE POUR CONFINER LES DÉVERSEMENTS ACCIDENTELS DE PÉTROLE BRUT, DE PRODUITS PÉTROLIERS OU AGENTS CHIMIQUES
  申请人：UNIV GEORGETOWN

  公开号：WO2012047251A1

  公开（公告）日：2012-04-12

  Low molecular weight gelators, methods of making such gelators, organogels comprising such gelators and systems and methods of using such gelators for the containment and/or remediation of a release and/or spill of a crude oil, a petroleum product and/or a chemical is described. In exemplary systems and methods, gels and/or emulsions formed from the combination and/or contact of such gelators and at least one of a crude oil, a petroleum product and a chemical from a release and/or spill into the environment can be used to recover these oils or chemicals while allowing the gelators to be recovered and reused to clean up or contain additional crude oil, petroleum products or chemicals.

  低分子量凝胶剂，制备此类凝胶剂的方法，包含此类凝胶剂的有机凝胶以及使用此类凝胶剂进行原油、石油产品和/或化学品泄漏和/或溢出的控制和/或治理的系统和方法已被描述。在示例系统和方法中，从此类凝胶剂的组合和/或接触与原油、石油产品和化学品之一泄漏和/或溢出到环境中形成的凝胶和/或乳化物可以用于回收这些油或化学品，同时允许回收和重复使用凝胶剂来清理或控制额外的原油、石油产品或化学品。
• FAST RECOVERY OF THIXOTROPY BY ORGANOGELS WITH LOW MOLECULAR WEIGHT GELATORS
  申请人：Weiss Richard G.

  公开号：US20110251294A1

  公开（公告）日：2011-10-13

  Low molecular weight gelators, methods of making such gelators, organogels comprising such gelators and methods of using such organogels are described. In exemplary methods, the gelators can be used in a variety of applications including the delivery of pharmaceutical active pharmaceutical ingredients, in food, cosmetics and consumer products, and in containing the unexpected release of chemical that occur for example in spills.

  本文描述了低分子量凝胶剂、制备这种凝胶剂的方法、包含这种凝胶剂的有机凝胶以及使用这种有机凝胶的方法。在示例方法中，这种凝胶剂可以用于各种应用，包括传递药物活性药物成分、食品、化妆品和消费品，以及包含意外泄漏化学品的方法，例如在泄漏中发生的情况。
• Water-activatable hot-melt adhesives
  申请人：Malcolm Nicol & Co., Inc.

  公开号：EP0050862A1

  公开（公告）日：1982-05-05

  A water-activatable, hot-melt, applied adhesive composition includes at least 30 to 60 percent by weight of a water-sensitive vinyl pyrrolidone/vinyl acetate copolymer wherein the weight ratio of the vinyl pyrrolidone moiety to the vinyl acetate moiety ranges from between about 3:1 to 1:3 and a wax of at least 10-30 percent by weight, and is characterized by the polymer being present up to 70 percent by weight, and a) 0 to 25 wt% of an ethylene/vinyl acetate copolymer containing from about 17 to 40 wt% of vinyl acetate; b) 5 to 12 wt% of at least one free, monobasic, saturated, long chain, fatty acid having at least 14 carbon atoms in the chain, the fatty acid having an acid number greater than about 160; and wherein c) the wax is preferably present 0 to 30 percent by weight, and is selected from the group consisting of solid water-soluble polyethylene glycol waxes and water-insoluble ester waxes.

  一种可用水活化的热熔粘合剂组合物，包括至少 30%至 60%（按重量计）的对水敏感的吡咯烷酮/醋酸乙烯共聚物，其中吡咯烷酮分子与醋酸乙烯分子的重量比约为 3:1 至 1:3，以及至少 10%至 30%（按重量计）的蜡，其特征在于聚合物的含量最高可达 70%（按重量计），以及 a) 0 至 25 wt%的乙烯/醋酸乙烯共聚物，其中醋酸乙烯含量约为 17 至 40 wt%； b) 5 至 12 wt%的至少一种游离、单基、饱和、长链脂肪酸，其链中至少有 14 个碳原子，该脂肪酸的酸值大于约 160；其中 c) 蜡的含量最好为 0-30% （重量百分比），选自固体水溶性聚乙二醇蜡和不溶于水的酯蜡。
• Fabric softening composition and detergent-composition comprising the same
  申请人：AKZO N.V.

  公开号：EP0258500A1

  公开（公告）日：1988-03-09

  A detergent compatible granular fabric softening composition, comprising a water soluble quaternary ammonium compound, a clay having an ion exchange capacity of at least 50 meq./100g and one or more amides, imides and urea derivatives according to four specifically defined formulae. A preferred group of amides to be applied are those according to the formula wherein R₁ and R₂ are the same or different and represent C₁-C₂₂ alkyl groups and wherein R₂ additionally may represent hydrogen and wherein R₃ represents hydrogen, C₁-C₂₂ alkyl, -(C₂H₄O)xH or -(C₃H₆O)xH wherein x has a value of 1 to 25, with the proviso that the sum of the carbon atoms of two radicals of R₁, R₂ and R₃ is at least 16. More preferred are N-stearyl­stearamide or N-oleylpalmitamide. Additionally the invention relates to detergent-compositions comprising these softening compositions in an amount from 0.5 to 50% by weight and preferably 2-20% by weight.

  一种与洗涤剂相容的颗粒状织物软化组合物，包括一种水溶性季铵化合物、一种离子交换容量至少为 50 meq./100g 的粘土和一种或多种酰胺、亚胺和脲衍生物，它们符合四种特定的定义式。 优先使用的酰胺类是符合以下式子的酰胺类 其中 R₁ 和 R₂ 相同或不同，代表 C₁-C₂₂烷基，R₂ 还可以代表氢，R₃ 代表氢、C₁-C₂₂烷基、-(C₂H₄O)xH 或 -(C₃H₆O)xH 其中 x 的值为 1 至 25，但 R₁、R₂ 和 R₃ 的两个基的碳原子之和至少为 16。更优选的是 N-硬脂酰硬脂酰胺或 N-油酰棕榈酰胺。 此外，本发明还涉及包含这些软化组合物的洗涤剂组合物，其用量为 0.5%至 50%（按重量计），最好为 2%至 20%（按重量计）。