17-(16-羧基十六烷基二硫烷基)十七烷酸 | 112122-99-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 17-(16-羧基十六烷基二硫烷基)十七烷酸
• 中文别名: 16-羧基十六烷基二硫化物
• 英文名称: 17,17'-Disulfanediyldiheptadecanoic acid
• 英文别名: 17-(16-carboxyhexadecyldisulfanyl)heptadecanoic acid
• CAS: 112122-99-3
• 化学式: C₃₄H₆₆O₄S₂
• 分子量: 603.0
• InChiKey: XPHZNCZEWTXFON-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14
• 重原子数：
  40
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  125
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• [EN] CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF<br/>[FR] CELLULES MARQUÉES PAR DES CONJUGUÉS LIPIDIQUES ET MÉTHODES D'UTILISATION DE CES DERNIÈRES
  申请人：UNIV CALIFORNIA

  公开号：WO2017079419A1

  公开（公告）日：2017-05-11

  A method of labelling a cell is provided. Aspects of the method include the contacting the cell with a cholesteryl-cargo conjugate having the formula: C-L-Z (I) wherein C is a cholesterylamine anchor group, L is an optional linker and Z is a linked cargo moiety to non-covalently bind the cholesterylamine anchoring group to the cell membrane thereby displaying Z at the cell surface for an extended period of time. Aspects of the method further include administering the labelled cell to a subject. Also provided is a method of modulating an immune response in a subject and a method of targeting a cell in a subject. Cholesterylamine conjugates, labelled cells and kits including the same that find use in the subject methods are also provided.

  提供了一种标记细胞的方法。该方法的方面包括使用具有以下公式的胆固醇-货物共轭物与细胞接触：C-L-Z（I），其中C是胆固醇胺锚定基，L是可选的连接物，Z是连接的货物基团，以非共价方式结合胆固醇胺锚定基到细胞膜上，从而在细胞表面显示Z，并延长其时间。该方法的方面还包括将标记的细胞给予受试者。还提供了一种调节受试者免疫反应的方法和一种在受试者中定位细胞的方法。还提供了胆固醇胺共轭物、标记的细胞和包括它们的试剂盒，这些试剂盒在上述方法中有用。
• PROCESS FOR PRODUCING LAYERED PRODUCT, LAYERED PRODUCT, PROCESS FOR PRODUCING LAYERED PRODUCT WITH DEVICE USING SAID LAYERED PRODUCT, AND LAYERED PRODUCT WITH DEVICE
  申请人：Toyobo Co., Ltd.

  公开号：EP2865523A1

  公开（公告）日：2015-04-29

  There is provided a polyimide layered product with a support which has a smooth surface to enable a sophisticated device to be formed thereon and in which the layered polyimide does not peel off even in a high-temperature process on device formation, and furthermore, the polyimide layered product can be peeled off easily from the support after the device is formed on the polyimide layered product. By preparing a polyimide film with a face at the support side and subjected to a surface treatment; subjecting at least one of a face of the support and the face of the polyimide film which are opposite to each other to a patterning treatment using a coupling agent to form a satisfactorily bondable part and an easily releasable part which differ in adhesion/peel strength; subsequently, superposing the support and the polyimide film to be subjected to a pressurizing/heating treatment and to be bonded to each other; subjecting the surface of the polyimide film to an organic alkali treatment; and then, applying a polyamic acid solution free from a slip agent ingredient, drying the coating film and imidizing the film, a layered product having a structure of at least three layers in which at least one layer contains a slip agent material and both surface layers have no slip agent material is produced.

  本发明提供了一种具有支撑面的聚酰亚胺分层产品，该支撑面表面光滑，可在其上形成精密装置，而且即使在装置形成的高温过程中，分层聚酰亚胺也不会剥落，此外，在聚酰亚胺分层产品上形成装置后，聚酰亚胺分层产品可以很容易地从支撑面上剥落。通过制备表面位于支撑面的聚酰亚胺薄膜并对其进行表面处理；使用偶联剂对支撑面和聚酰亚胺薄膜相对面中的至少一个面进行图案化处理，以形成粘合力/剥离强度不同的可粘合部分和易剥离部分；然后，将支撑面和聚酰亚胺薄膜叠加在一起，进行加压/加热处理并相互粘合；将聚酰亚胺薄膜的表面进行有机碱处理；然后，涂上不含防滑剂成分的聚酰胺酸溶液，干燥涂膜并使薄膜酰亚胺化，这样就制成了一种具有至少三层结构的分层产品，其中至少一层含有防滑剂材料，而两层表面均不含防滑剂材料。
• PROCESS FOR PRODUCING LAYERED PRODUCT AND LAYERED PRODUCT
  申请人：Toyobo Co., Ltd.

  公开号：EP2865523B1

  公开（公告）日：2018-06-06
• CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF
  申请人：The Regents of the University of California

  公开号：EP3370764A1

  公开（公告）日：2018-09-12
• Asymmetrically Functionalized NanoParticles
  申请人：Shumaker-Parry Jennifer S.

  公开号：US20090256116A1

  公开（公告）日：2009-10-15

  The invention provides methods and compositions having at least one asymmetrically functionalized nanoparticle. An asymmetrically functionalized nanoparticle can comprise a nanoparticle core having an outer surface, a primary group of first ligands attached to a substantially continuous primary region of the outer surface, and a secondary group of second ligands attached to a substantially continuous secondary region of the outer surface, such that the primary group of first ligands and the secondary group of second ligands comprise a different ligand population.