1H-吡咯-1-乙酰胺,N-[2-[(2,5-二羰基-1-吡咯烷基)氧代]-2-羰基乙基]-2,5-二氢-2,5-二羰基- | 139112-39-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 1H-吡咯-1-乙酰胺,N-[2-[(2,5-二羰基-1-吡咯烷基)氧代]-2-羰基乙基]-2,5-二氢-2,5-二羰基-
• 英文名称: 1H-Pyrrole-1-acetamide, N-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-2,5-dihydro-2,5-dioxo-
• 英文别名: (2,5-dioxopyrrolidin-1-yl) 2-[[2-(2,5-dioxopyrrol-1-yl)acetyl]amino]acetate
• CAS: 139112-39-3
• 化学式: C₁₂H₁₁N₃O₇
• 分子量: 309.23
• InChiKey: NZJYENKDVVYFFD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  130
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• Antibodies to Olanzapine Haptens and Use Thereof
  申请人：Janssen Pharmaceutica NV

  公开号：US20140057303A1

  公开（公告）日：2014-02-27

  Disclosed is an antibody which binds to olanzapine, which can be used to detect olanzapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of olanzapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.

  揭示了一种与奥氮平结合的抗体，可用于在样本中检测奥氮平，例如在竞争性免疫分析方法中使用。该抗体可用于侧向流动测定装置，用于奥氮平的现场检测，包括在单个侧向流动测定装置中多重检测阿立哌唑、奥氮平、奎硫平和利培酮。
• Antibodies to Quetiapine Haptens and Use Thereof
  申请人：Janssen Pharmaceutica NV

  公开号：US20140057305A1

  公开（公告）日：2014-02-27

  Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.

  揭示了一种与奎替亚平结合的抗体，可用于在样本中检测奎替亚平，例如在竞争性免疫分析方法中使用。该抗体可用于侧向流动测定装置中，用于奎替亚平的现场检测，包括在单个侧向流动测定装置中多重检测阿立哌唑、奥兰扎平、奎替亚平和利培酮。
• Antibodies to Risperidone Haptens and Use Thereof
  申请人：Janssen Pharmaceutica NV

  公开号：US20140057301A1

  公开（公告）日：2014-02-27

  Disclosed is an antibody which binds to risperidone, which can be used to detect risperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of risperidone, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.

  揭示了一种与利培酮结合的抗体，可用于在样本中检测利培酮，例如在竞争性免疫分析方法中。该抗体可用于侧向流动检测装置中，用于快速检测利培酮，包括在单个侧向流动检测装置中多重检测阿立哌唑、奥氮平、喹硫平和利培酮。
• Antibodies to Aripiprazole Haptens and Use Thereof
  申请人：Janssen Pharmaceutica NV

  公开号：US20140057299A1

  公开（公告）日：2014-02-27

  Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.

  揭示的是一种与阿立哌唑结合的抗体，可用于检测样本中的阿立哌唑，例如在竞争性免疫分析方法中使用。该抗体可用于侧向流动测定装置，用于现场检测阿立哌唑，包括在单个侧向流动测定装置中多重检测阿立哌唑、奥兰扎平、奎哌齐和利培酮。
• Antibodies to Paliperidone Haptens and Use Thereof
  申请人：Janssen Pharmaceutica NV

  公开号：US20140057297A1

  公开（公告）日：2014-02-27

  Disclosed is an antibody which binds to paliperidone, which can be used to detect paliperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of paliperidone, including multiplex detection of aripiprazole, olanzapine, quetiapine, risperidone and paliperidone in a single lateral flow assay device.

  本文披露了一种与帕利哌酮结合的抗体，可用于检测样本中的帕利哌酮，例如在竞争性免疫分析方法中使用。该抗体可用于侧流检测装置中，用于在点对点检测帕利哌酮，包括在单个侧流检测装置中多重检测阿立哌唑、奥兰扎平、喹硫平、利培酮和帕利哌酮。