2,2,5,5-四甲基-4-苯基-2,5-二氢-1H-咪唑-1-醇 | 39753-68-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,2,5,5-四甲基-4-苯基-2,5-二氢-1H-咪唑-1-醇
• 英文名称: 1-hydroxy-4-phenyl-2,2,5,5-tetramethyl-3-imidazoline
• 英文别名: 1-hydroxy-2,2,5,5-tetramethyl-4-phenyl-3-imidazoline；1-Hydroxy-2.2.5.5-tetramethyl-4-phenyl-3-imidazolin；2,2,5,5-tetramethyl-4-phenyl-2,5-dihydro-imidazol-1-ol；1-hydroxy-2,2,5,5-tetramethyl-4-phenylimidazole
• CAS: 39753-68-9
• 化学式: C₁₃H₁₈N₂O
• mdl: MFCD02258433
• 分子量: 218.299
• InChiKey: CVWOZKTYHKOFFX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.461
• 拓扑面积：
  35.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,2,5,5-四甲基-4-苯基-2,5-二氢-1H-咪唑-1-醇 在 manganese(IV) oxide 、 正丁基锂 、 硝酸甲酯 、 一水合肼 作用下， 以 乙醇 为溶剂， 反应 29.5h， 生成
  参考文献：
  名称：

  4-(oR-苯基)-3-咪唑啉的合成及再环化反应

  摘要：

  摘要1-羟基-4-苯基-3-咪唑啉与丁基锂反应生成苯基的正金属化产物。该化合物与亲电试剂反应，然后氧化得到硝酰基自由基的 4-(oR-苯基) 衍生物。当邻位存在羟烷基时，由于螺双环互变异构体的存在，观察到咪唑啉系列的稳定硝酰基自由基衰变的不寻常途径。theo-金属化衍生物与 CS2 的反应导致咪唑啉环的深刻转变和异吲哚硫酮的形成。在 3-咪唑啉的 4-（邻苯甲酰基）苯基衍生物的情况下，会发生快速再循环成异喹啉。

  DOI：

  10.1007/bf00717352
• 作为产物：
  描述：

  2,2,5,5-四甲基-4-苯基-3-咪唑-1-氧自由基 生成 2,2,5,5-四甲基-4-苯基-2,5-二氢-1H-咪唑-1-醇
  参考文献：
  名称：

  Influence of radical center on oxidative properties of nitron group in reaction of nitroxyl radicals of 3-imidazoline 3-oxide withhydrazine

  摘要：

  DOI：

  10.1007/bf00956162

文献信息

• Inhibition of pulp and paper yellowing using nitroxides, hydroxylamines and other coadditives
  申请人：——

  公开号：US20020124980A1

  公开（公告）日：2002-09-12

  Pulps or papers, especially chemimechanical or thermomechanical pulps or papers, which still contain lignin, have enhanced resistance to yellowing when they contain an effective stabilizing amount of a hindered amine compound which preferably is a nitroxide, a hydroxylamine or an ammonium salt thereof. This performance is often further enhanced by the presence of one or more coadditives selected from the group consisting of the UV absorbers, the polymeric inhibitors, the nitrones, the fluorescent whitening agents, metal chelating agents, sulfur containing stabilizers, metal salts and diene compounds. Combinations of nitroxides, hydroxylamines or their salts, benzotriazole or benzophenone UV absorbers and a metal chelating agent are particularly effective. Selected derivatives of 1-oxyl-2,2,6,6-tetramethyl-piperidin-4-ol and selected hydroxylamine salts are novel compounds and are surprisingly effective for this purpose.

  含有木质素的纸浆或纸张，特别是化学机械或热机械纸浆或纸张，如果它们含有有效的阻化胺化合物（最好是亚硝基自由基，羟胺或其铵盐），则具有增强的抗黄变性能。当与来自紫外线吸收剂、聚合抑制剂、亚硝基醇、荧光增白剂、金属螯合剂、含硫稳定剂、金属盐和二烯化合物等组成的一种或多种协同添加剂一起使用时，通常可以进一步提高其性能。亚硝基自由基、羟胺或其盐、苯并三唑或苯并酚类紫外线吸收剂和金属螯合剂的组合尤其有效。选择的1-氧基-2,2,6,6-四甲基哌啶-4-醇和选择的羟胺盐衍生物是新的化合物，出乎意料地有效。
• Dikanov, S. A.; Grigor'ev, I. A.; Volodarskii, L. B., Russian Journal of Physical Chemistry, 1982, vol. 56, # 11, p. 1696 - 1699
  作者：Dikanov, S. A.、Grigor'ev, I. A.、Volodarskii, L. B.、Tsvetkov, Yu. D.

  DOI：——

  日期：——
• Effect of the chemical structure of nitroxyl radicals on their reactivity in the reaction with hydrazobenzene and tetranitromethane
  作者：A. D. Malievskii、S. V. Koroteev、L. B. Volodarskii、A. B. Shapiro

  DOI：10.1007/bf00958847

  日期：1990.11

  The reaction rate constants of reduction of stable radicals of different classes by hydrazobenzene in hexane at approximately 20-degrees-C, in the range of 0.4-5.10(3) M-1.sec-1, were determined; a single scale of the oxidative properties of stable nitroxyl radicals was constructed. The rate constants of oxidation of a series of nitroxyl radicals by tetranitromethane in aqueous medium at approximately 20-degrees-C, in the range of 0.06-10 M-1.sec-1, were determined. It was shown that the oxidative properties of the nitroxyl group decrease slightly with an increase in its reducing properties for nitroxyl radicals of the piperidine and imidazoline series in reactions with ascorbic acid and tetranitromethane in aqueous medium, respectively.
• Influence of the radical center on the basic hydrolysis reaction of 4-dihalomethyl-3-imidazoline-3-oxide
  作者：I. A. Grigor'ev、G. I. Shchukin、L. B. Volodarskii

  DOI：10.1007/bf00954482

  日期：1983.12
• Convenient means of converting nitroxyl radicals into O-methylhydroxylamines
  作者：G. I. Shchukin、I. A. Grigor'ev、L. B. Volodarskii

  DOI：10.1007/bf00955785

  日期：1983.10