2,3-二氢-2-甲基-5-苯并呋喃胺 | 26210-77-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 香豆素
• 中文名称: 2,3-二氢-2-甲基-5-苯并呋喃胺
• 英文名称: 2-methyl-2,3-dihydro-benzofuran-5-ylamine
• 英文别名: 2-Methyl-5-amino-cumaran；(2-Methyl-2,3-dihydro-1-benzofuran-5-YL)amine；2-methyl-2,3-dihydro-1-benzofuran-5-amine
• CAS: 26210-77-5
• 化学式: C₉H₁₁NO
• 分子量: 149.192
• InChiKey: LSYQSRCIPQPFMO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,3-二氢-2-甲基-5-苯并呋喃胺 在 盐酸 作用下， 以 苯 为溶剂， 反应 162.0h， 生成 Methyl-[1-[(2-methyl-2,3-dihydro-1-benzofuran-5-yl)amino]-1-oxohexan-2-yl]azanium;chloride
  参考文献：
  名称：

  Synthesis of amino-substituted 2-methylcoumarins, chromans, and benzoxepanes and their N-(alkylaminoacyl) derivatives

  摘要：

  DOI：

  10.1007/bf00761981
• 作为产物：
  描述：

  4-(烯丙氧基)苯胺 在 Si:Al = 22:1 HZSM-5 作用下， 以 水 为溶剂， 反应 0.25h， 以90%的产率得到2,3-二氢-2-甲基-5-苯并呋喃胺
  参考文献：
  名称：

  亚临界水中烯丙基苯基醚的催化串联克莱森重排-分子内氢芳基氧基化反应生产二氢苯并呋喃†

  摘要：

  我们在此报告了一种温和的方法，该方法通过水热催化串联Claisen重排-烯丙基苯基醚的分子内氢芳氧基化来制备二氢苯并呋喃。该反应提供了构建二氢苯并呋喃的新方法，该方法可能适用于天然产物的合成。选择SBA-15，TS-1，HZSM-5作为200-320°C水热反应介质中的催化剂。HZSM-5催化剂表现出最高的催化活性，研究了烯丙基苯基醚-水的摩尔比，时间，压力，温度和催化剂对水热条件下克莱森加氢芳氧基化反应的影响。后两个过程变量对产品的产量和分布影响最大。

  DOI：

  10.1039/c4ra04689g

文献信息

• Oxidation dyeing process using a composition comprising a monoaminobenzene and a metal catalyst
  申请人：L'OREAL

  公开号：US10251827B2

  公开（公告）日：2019-04-09

  The invention relates to a process for dyeing keratin fibers, comprising the use of one or more metal catalysts and of a composition (A) comprising: —one or more oxidizing agents, and —at least one monoaminobenzene of formula (I), or an addition salt or solvate thereof in which the radicals R1 to R5 represent, independently of each other: a hydrogen atom; a halogen atom, a C1-C6 alkyl radical, a C1-C6 alkoxy radical, a carboxylic radical (—COOH), a sulfonic radical (—S03 H); two of the adjacent radicals R1 to R5 possibly forming, with the carbon atoms that bear them, a saturated or unsaturated 5- to 7-membered ring, optionally comprising from 1 to 2 heteroatoms, preferably oxygen, the said ring being optionally fused with a saturated or unsaturated 5- to 6-membered ring; on condition that at least one of the radicals R1 to R5 represents an optionally substituted alkoxy radical and preferably at least one of the other radicals R1 to R5 is a hydrogen atom.

  本发明涉及一种角蛋白纤维染色工艺，包括使用一种或多种金属催化剂和一种组合物（A），组合物（A）包括： -一种或多种氧化剂，和 -至少一种式（I）的单胺苯，或其加成盐或溶液，其中自由基 R1 至 R5 各自代表：氢原子、卤素原子、C1-C6 烷基、C1-C6 烷氧基、羧基 (-COOH)、磺酸基 (-S03 H)；R1 至 R5 中相邻的两个基团可与含有它们的碳原子形成饱和或不饱和的 5 至 7 元环，可选择包含 1 至 2 个杂原子，最好是氧，所述环可选择与饱和或不饱和的 5 至 6 元环融合；条件是 R1 至 R5 自由基中至少有一个代表任选取代的烷氧基，且 R1 至 R5 自由基中至少有一个是氢原子。
• DAUKSHAS V. K.; PYATRAUSKAS O. YU.; PURVANYATSKAS G. V., XIMIYA GETEROTSIKL. SOED.,(1987) N 3, 320-324
  作者：DAUKSHAS V. K.、 PYATRAUSKAS O. YU.、 PURVANYATSKAS G. V.

  DOI：——

  日期：——
• OXIDATION DYEING PROCESS USING A COMPOSITION COMPRISING A MONOAMINOBENZENE AND A METAL CATALYST
  申请人：L'OREAL

  公开号：US20160128922A1

  公开（公告）日：2016-05-12

  The invention relates to a process for dyeing keratin fibres, comprising the use of one or more metal catalysts and of a composition (A) comprising: —one or more oxidizing agents, and —at least one monoaminobenzene of formula (I), or an addition salt or solvate thereof in which the radicals R1 to R5 represent, independently of each other: a hydrogen atom; a halogen atom, a C1-C6 alkyl radical, a C1-C6 alkoxy radical, a carboxylic radical (—COOH), a sulfonic radical (—SO3 H); two of the adjacent radicals R1 to R5 possibly forming, with the carbon atoms that bear them, a saturated or unsaturated 5- to 7-membered ring, optionally comprising from 1 to 2 heteroatoms, preferably oxygen, the said ring being optionally fused with a saturated or unsaturated 5- to 6-membered ring; on condition that at least one of the radicals R1 to R5 represents an optionally substituted alkoxy radical and preferably at least one of the other radicals R1 to R5 is a hydrogen atom.
• [EN] OXIDATION DYEING PROCESS USING A COMPOSITION COMPRISING A MONOAMINOBENZENE AND A METAL CATALYST<br/>[FR] PROCÉDÉ DE COLORATION PAR OXYDATION À L'AIDE D'UNE COMPOSITION COMPRENANT UN MONOAMINOBENZÈNE ET UN CATALYSEUR MÉTALLIQUE
  申请人：OREAL

  公开号：WO2014202787A1

  公开（公告）日：2014-12-24

  The invention relates to a process for dyeing keratin fibres, comprising the use of one or more metal catalysts and o f a composition (A) comprising : - one or more oxidizing agents, and - at least one monoaminobenzene of formula (I), or an addition salt or solvate thereof in which the radicals R1 to R5 represent, independently of each other: a hydrogen atom; a halogen atom, a C1-C6 alkyl radical, a C1-C6 alkoxy radical, a carboxylic radical (-COOH), a sulfonic radical (-S03 H); two of the adjacent radicals R1 to R5 possibly forming, with the carbon atoms that bear them, a saturated or unsaturated 5- to 7-membered ring, optionally comprising from 1 to 2 heteroatoms, preferably oxygen, the said ring being optionally fused with a saturated or unsaturated 5- to 6- membered ring; on condition that at least one of the radicals R1 to R5 represents an optionally substituted alkoxy radical and preferably at least one of the other radicals R1 to R5 is a hydrogen atom.
• Synthesis of amino-substituted 2-methylcoumarins, chromans, and benzoxepanes and their N-(alkylaminoacyl) derivatives
  作者：V. K. Daukshas、O. Yu. Pyatrauskas、G. V. Purvanyatskas

  DOI：10.1007/bf00761981

  日期：1987.3