2,3-二甲基-5-丙基-吡嗪 | 32262-98-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: 2,3-二甲基-5-丙基-吡嗪
• 英文名称: 2,3-dimethyl-5-n-propylpyrazine
• 英文别名: 2,3-Dimethyl-5-propylpyrazine；2,3-dimethyl-5-propyl-pyrazine；2,3-Dimethyl-5-n-propylpyrazin；Dimethyl-2,3-propyl-5-pyrazin
• CAS: 32262-98-9
• 化学式: C₉H₁₄N₂
• mdl: MFCD18449258
• 分子量: 150.224
• InChiKey: RHCYSZMTNWMCOO-UHFFFAOYSA-N

物化性质

• 沸点：
  211.5±35.0 °C(Predicted)
• 密度：
  0.952±0.06 g/cm3(Predicted)
• 保留指数：
  1154

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.555
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

反应信息

• 作为产物：
  描述：

  2,3-二甲基-5-羟基吡嗪 在 吡啶 、 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) 作用下， 以 四氢呋喃 、 氯仿 为溶剂， 反应 14.5h， 生成 2,3-二甲基-5-丙基-吡嗪
  参考文献：
  名称：

  Regioselective Synthesis of Trialkylpyrazines via Nickel-Catalyzed Negishi Cross-Coupling of Pyrazine Triflate

  摘要：

  A regioselective synthesis of trialkylpyrazines via nickel-catalyzed cross-coupling reaction of pyrazine triflate is reported. The 5-substituted 2,3-dimethylpyrazine derivatives including trail pheromone components of the ant Eutetramorium mocquerysi have been successfully synthesized in good yields by nickel-catalyzed Negishi cross-coupling reactions of pyrazine triflate mediated by alkyl and arylzinc halides.

  DOI：

  10.1055/s-0031-1290972

文献信息

• FLAMENT I.; SONNAY PH.; OHLOFF G., BULL. SOC. CHIM. BELG., 1979, 88, NO 11, 941-950
  作者：FLAMENT I.、 SONNAY PH.、 OHLOFF G.

  DOI：——

  日期：——
• MASUDA HIDEKI; TANAKA MASATA; AKIYAMA TAKUYA; SHIBAMOTO TAKAYUKI, J. AGR. AND FOOD CHEM., 1980, 28, NO 2, 244-246
  作者：MASUDA HIDEKI、 TANAKA MASATA、 AKIYAMA TAKUYA、 SHIBAMOTO TAKAYUKI

  DOI：——

  日期：——
• VOLATILE ORGANIC COMPOUNDS FROM BACTERIAL ANTAGONISTS FOR CONTROLLING MICROBIAL GROWTH
  申请人：Research Center Pharmaceutical Engineering GmbH

  公开号：EP2654432A2

  公开（公告）日：2013-10-30
• [EN] VOLATILE ORGANIC COMPOUNDS FROM BACTERIAL ANTAGONISTS FOR CONTROLLING MICROBIAL GROWTH<br/>[FR] COMPOSÉS ORGANIQUES VOLATILS ISSUS D'ANTAGONISTES BACTÉRIENS POUR LUTTER CONTRE LA CROISSANCE BACTÉRIENNE
  申请人：RES CT PHARMACEUTICAL ENGINEERING GMBH

  公开号：WO2012085255A2

  公开（公告）日：2012-06-28

  The present invention relates to methods and compositions for controlling microbial growth on a surface to be treated. More particularly, the invention is directed to a corresponding method comprising contacting the surface to be treated with one or more antimicrobial agents; and incubating the surface for a pre-selected period of time, wherein the one or more antimicrobial agents are volatile organic compounds produced by plant-associated microorganisms. In further aspects, the invention relates to a kit-of-parts and a composition, respectively, each comprising one or more volatile organic compounds produced by plantassociated microorganisms as defined herein.
• Regioselective Synthesis of Trialkylpyrazines via Nickel-Catalyzed Negishi Cross-Coupling of Pyrazine Triflate
  作者：Kee-In Lee、Arigala Pitchaiah、In Hwang、Jin-Soo Hwang、Hyungrok Kim

  DOI：10.1055/s-0031-1290972

  日期：2012.6

  A regioselective synthesis of trialkylpyrazines via nickel-catalyzed cross-coupling reaction of pyrazine triflate is reported. The 5-substituted 2,3-dimethylpyrazine derivatives including trail pheromone components of the ant Eutetramorium mocquerysi have been successfully synthesized in good yields by nickel-catalyzed Negishi cross-coupling reactions of pyrazine triflate mediated by alkyl and arylzinc halides.

表征谱图