水杨酸异癸酯 | 85252-25-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 水杨酸异癸酯
• 英文名称: Isodecyl Salicylate
• 英文别名: isodecyl-ortho-hydroxy-benzoate；8-methylnonyl 2-hydroxybenzoate
• CAS: 85252-25-1
• 化学式: C₁₇H₂₆O₃
• 分子量: 278.392
• InChiKey: PJTNSWOJMXNNFG-UHFFFAOYSA-N

物化性质

• LogP：
  6.833 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  20
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  水杨酸甲酯 在 硫酸 、 magnesium sulfate 作用下， 生成 水杨酸异癸酯
  参考文献：
  名称：

  US2022/380290

  摘要：

  公开号：

文献信息

• [EN] SOLUBILIZING AGENTS FOR FUNCTIONAL ACTIVE COMPOUNDS<br/>[FR] AGENTS SOLUBILISANTS POUR COMPOSÉS ACTIFS FONCTIONNELS
  申请人：ISP INVESTMENTS INC

  公开号：WO2016201260A1

  公开（公告）日：2016-12-15

  A photo protective topical composition, comprising: (i) at least one functional active; and (ii) at least one solubilizing compound having the structure of Formula (I): wherein R is C5-C10 cycloalkyl or linear or branched alkylcycloalkyl, wherein the ring size is C5-C7; R1, R2, and R3 are each independently selected from the group consisting of H, and linear or branched C1-C4 alkyl, provided that at least two of R1, R2, R3 are H; wherein the solubilizing compound is present in an amount effective to solubilize said functional active. Also disclosed is a method for treating skin, lips, nails, hair, ears, eyelashes, eyebrows and/or scalp with an effective amount of composition.

  一种光保护性局部组合物，包括：（i）至少一种功能活性物质；和（ii）具有以下结构的至少一种溶解化合物（I）：其中R为C5-C10环烷基或直链或支链烷基环烷基，其中环大小为C5-C7；R1、R2和R3分别独立地选择自H、直链或支链C1-C4烷基的群，但至少两个R1、R2、R3为H；其中所述溶解化合物以有效量存在，以溶解所述功能活性物质。还公开了一种使用有效量的组合物治疗皮肤、嘴唇、指甲、头发、耳朵、睫毛、眉毛和/或头皮的方法。
• [EN] TOPICAL COMPOSITION<br/>[FR] COMPOSITION TOPIQUE
  申请人：DSM IP ASSETS BV

  公开号：WO2019180038A1

  公开（公告）日：2019-09-26

  The present invention relates to topical compositions comprising at least one polar oil and a micronized 1,4-di(benzoxazol-2'-yl)benzene having a mean particle size of at most 300 nm as well as to the use of such a micronized 1,4-di(benzoxazol-2'-yl)benzene to reduce the transfer of such oils to surfaces.

  本发明涉及含有至少一种极性油和平均粒径不超过300纳米的微粉化1,4-二（苯并噁唑-2'-基）苯的局部组合物，以及使用这种微粉化的1,4-二（苯并噁唑-2'-基）苯来减少这些油对表面的传递。
• Linkage of agents using microparticles
  申请人：Green Howard

  公开号：US20060110379A1

  公开（公告）日：2006-05-25

  Methods, products and kits are provided for attaching agents to a skin surface via microparticles using endogenous or exogenous transglutaminase.

  提供了一种方法、产品和套件，可通过内源或外源性谷氨酰胺转移酶使用微粒子将药剂附着到皮肤表面。
• Nanoparticle Compositions and Methods as Carriers of Nutraceutical Factors Across Cell Membranes and Biological Barriers
  申请人：NANOSPHERE HEALTH SCIENCES, LLC

  公开号：US20160263047A1

  公开（公告）日：2016-09-15

  Novel process and products thereby emplace nutraceutical factors within nanodelivery vehicles for various indications in mammals, including humans.

  新型的过程和产品将营养保健因素置于纳米递送载体中，以治疗哺乳动物，包括人类的各种症状。
• Compositions and method for the stimulation of the female and male sexual response
  申请人：Multichem S.A.S. di Gabriele Segalla

  公开号：EP2881107A1

  公开（公告）日：2015-06-10

  A description is given of compositions for topical use comprising menthyl nicotinate as primary active ingredient, in such a dose as to stimulate in a subject the sexual response, preferably in such a dose as to maximise this response in a relative short time, and at least one appropriate lipophilic vehicle such as to solubilise the menthyl nicotinate and allow a rapid absorption thereof in the epithelial tissues of the female and/or male erogenous zones.

  本文介绍了外用组合物，其主要活性成分是烟酸薄荷酯，其剂量可刺激受试者的性反应，最好是在相对较短的时间内使这种反应最大化；还包括至少一种适当的亲脂载体，可使烟酸薄荷酯溶解，并能被女性和/或男性性感区的上皮组织迅速吸收。