2,9-二氯-5,6,12,13-四氢奎并[2,3-b]吖啶-7,14-二酮 | 51222-59-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2,9-二氯-5,6,12,13-四氢奎并[2,3-b]吖啶-7,14-二酮
• 中文别名: 抗坏血酸硬脂酸酯
• 英文名称: Ascorbyl monostearate
• 英文别名: (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one;octadecanoic acid
• CAS: 51222-59-4
• 化学式: C24H44O8
• 分子量: 460.6
• InChiKey: CSTRPYAGFNTOEQ-MGMRMFRLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.93
• 重原子数：
  32
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  145
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• AMINOALKYL COMPOUND
  申请人：Daiichi Sankyo Company, Limited

  公开号：US20210040057A1

  公开（公告）日：2021-02-11

  The present invention directs to provide a novel compound for treating and/or preventing pain, having excellent skin permeation and reduced skin irritation. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof (R 1 : a methyl group or other like group, R 2 : a fluorine atom or other like group, R 3 : a methyl group or other like group, R 4 : a methyl group or other like group, R 5 : a methyl group or other like group)

  本发明旨在提供一种用于治疗和/或预防疼痛的新型化合物，具有出色的皮肤渗透性和降低的皮肤刺激性。本发明提供了一种具有以下结构的化合物（I）或其药学上可接受的盐（R1：甲基基团或类似基团，R2：氟原子或类似基团，R3：甲基基团或类似基团，R4：甲基基团或类似基团，R5：甲基基团或类似基团）。
• NOVEL PSEUDOCERAMIDE COMPOUND, AND EXTERNAL USE SKIN PREPARATION COMPOSITION CONTAINING SAME
  申请人：AE KYUNG INDUSTRIAL CO., LTD

  公开号：US20170313648A1

  公开（公告）日：2017-11-02

  The present invention relates to a novel pseudoceramide compound, and more particularly, to a novel pseudoceramide compound represented by formula 1 and having skin moisturizing and barrier function characteristics, and a skin topical composition comprising the pseudoceramide compound: wherein R 1 represents a linear C12-C18 alkyl group and has at least one double bond, and R 2 represents a linear C12-C22 alkyl group and has a double bond.

  本发明涉及一种新型伪神经酰胺化合物，更具体地说，涉及一种由式1表示的具有皮肤保湿和屏障功能特性的新型伪神经酰胺化合物，以及包括该伪神经酰胺化合物的皮肤局部组合物：其中R1代表线性C12-C18烷基基团且至少有一个双键，R2代表线性C12-C22烷基基团且有一个双键。
• [EN] METHOD OF PURIFYING REDUCED COENZYME Q<br/>[FR] METHODE DE PURIFICATION DE LA COENZYME Q REDUITE
  申请人：KANEKA CORP

  公开号：WO2004063131A1

  公开（公告）日：2004-07-29

  The object of the present invention is to provide a method of purifying reduced coenzyme Q10 to produce a high-quality product which is useful as an ingredient in foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, animal drugs, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc., by a efficient manner suitable for an industrial scale production. The present invention relates to a method of purifying reduced coenzyme Q10 which comprises washing crystals and/or oil of reduced coenzyme Q10 with a water-soluble organic solvent or a mixed solvent composed of a water-soluble organic solvent and water to thereby remove water-soluble impurities, especially a reducing agent or impurities derived from a reducing agent, from the crystals and/or oil of reduced coenzyme Q10. The present invention makes it possible to conveniently and efficiently purify reduced coenzyme Q1o in a manner excellent in operationality, and to obtain a high-quality reduced coenzyme Q10.

  本发明的目的是提供一种将还原辅酶Q10纯化以生产高质量产品的方法，该产品可用作食品、功能性营养食品、特定健康食品、营养补充剂、营养品、动物药品、饮料、饲料、化妆品、药品、药物疗法、预防药物等的成分，通过适合工业规模生产的高效方法。本发明涉及一种纯化还原辅酶Q10的方法，包括用水溶性有机溶剂或由水溶性有机溶剂和水组成的混合溶剂清洗还原辅酶Q10的晶体和/或油，以去除晶体和/或油中的水溶性杂质，特别是来自还原剂或还原剂衍生物的杂质。本发明使得可以方便高效地纯化还原辅酶Q10，具有出色的操作性，并获得高质量的还原辅酶Q10。
• ANTIMICROBIAL COMPOSITION CONTAINING 7,10-EPOXYOCTADECA-7,9-DIENOIC ACID AS ACTIVE INGREDIENT
  申请人：KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

  公开号：US20190133989A1

  公开（公告）日：2019-05-09

  The present invention relates to an antimicrobial composition comprising, as an active ingredient, 7,10-epoxyoctadeca-7,9-dienoic acid or a combination of 7,10-epoxyoctadeca-7,9-dienoic acid and another antibiotic. The growth of bacteria can be effectively inhibited regardless of the class of antibiotics when using the antimicrobial composition of the present invention. Therefore, the antimicrobial composition of the present invention can be useful in related pharmaceutical, food and cosmetic industries requiring the inhibition of bacterial growth.

  本发明涉及一种抗微生物组合物，其包括作为活性成分的7,10-环氧-7,9-十八碳二烯酸或7,10-环氧-7,9-十八碳二烯酸和另一种抗生素的组合物。使用本发明的抗微生物组合物时，可以有效地抑制细菌的生长，无论抗生素的类别如何。因此，本发明的抗微生物组合物可以在需要抑制细菌生长的相关制药、食品和化妆品行业中发挥作用。
• Isoprenylcarboxylic acid-containing composition for external use
  申请人：Eisai Co., Ltd.

  公开号：EP0090378A1

  公开（公告）日：1983-10-05

  An isoprenylcarboxylic acid-containing composition for external use is disclosed which contains antioxidant(s) selected from the group consisting of butylated hydroxytoluene, butylated hydroxyanisole, ascorbic acid/fatty acid esters, tocopherol and gallic acid esters, and/or antioxidant(s) selected from the group consisting of ascorbic acid, sodium ascorbate, erythorbic acid, sodium erythorbate, cysteine, sodium hydrogensulfite and sodium metabisulfite, either alone or in combination.

  本发明公开了一种含异戊烯羧酸的外用组合物，它含有选自丁基化羟基甲苯、丁基化羟基茴香醚、抗坏血酸/脂肪酸酯、生育酚和没食子酸酯，和/或选自抗坏血酸、抗坏血酸钠、赤藓红酸、赤藓红酸钠、半胱氨酸、亚硫酸氢钠和焦亚硫酸钠组成的组的抗氧化剂，可以单独使用，也可以混合使用。