(E)-[3,4-bis(phenylmethoxy)phenyl]methylidenehydrazine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (E)-[3,4-bis(phenylmethoxy)phenyl]methylidenehydrazine
• 化学式: C₂₁H₂₀N₂O₂
• 分子量: 332.4
• InChiKey: BXQMCEPKLKNJSA-OEAKJJBVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  56.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES, AS WELL AS THEIR THERAPEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR PRODUCTION THE ACTIVE AGENT<br/>[FR] DERIVES DE 7H-PYRROLO[2,3-D]PYRIMIDINE ET LEURS SELS ACCEPTABLES D'UN POINT DE VUE THERAPEUTIQUE, PREPARATIONS PHARMACEUTIQUES LES CONTENANT ET PROCEDE DE PRODUCTION DE L'AGENT ACTIF
  申请人：SZOLCSANYI JANOS

  公开号：WO2005105804A1

  公开（公告）日：2005-11-10

  The invention relates to new 7H-pyrrolo[2,3-d]pyrimidine derivatives, as well as their therapeutically acceptable salts, pharmaceutical preparations containing them and process for producing the active agent. The pharmaceutical preparation is adventageously antiphlogistic and analgetic one, a preparation reducing neuropathic hyperalgesia and rheumatic arthritis, a preparation for hindering destruction of bones chondrus, being applicable for treatment of other diseases, which may be connected with other inflammatory processes e.g. asthma, eczema or psoriasis.

  这项发明涉及新的7H-吡咯[2,3-d]嘧啶衍生物，以及它们的治疗可接受的盐、含有它们的药物制剂和生产活性剂的过程。药物制剂具有抗炎和镇痛的优势，可减少神经病性过敏和类风湿性关节炎，可用于阻止骨骨软骨的破坏的制剂，适用于治疗可能与其他炎症过程相关的其他疾病，例如哮喘、湿疹或牛皮癣。
• 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES, AS WELL AS THEIR THERAPEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR PRODUCTION THE ACTIVE AGENT
  申请人：Szolcsanyi, Janos

  公开号：EP1756110A1

  公开（公告）日：2007-02-28