2-(2-呋喃基亚甲基氨基)乙酸 | 375365-51-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2-(2-呋喃基亚甲基氨基)乙酸
• 英文名称: {[1-Furan-2-yl-meth-(E)-ylidene]-amino}-acetic acid
• 英文别名: Glycine, N-(2-furanylmethylene)-；2-(furan-2-ylmethylideneamino)acetic acid
• CAS: 375365-51-8
• 化学式: C₇H₇NO₃
• 分子量: 153.137
• InChiKey: HBKWGWXLBXMSTG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  62.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  二乙氧基二甲基硅烷 、 2-(2-呋喃基亚甲基氨基)乙酸 以 苯 为溶剂， 生成 [[2-(Furan-2-ylmethylideneamino)acetyl]oxy-dimethylsilyl] 2-(furan-2-ylmethylideneamino)acetate
  参考文献：
  名称：

  COORDINATION BEHAVIOR OF BIOLOGICALLY ACTIVE SCHIFF BASES OF AMINO ACIDS TOWARDS SILICON(IV) ION

  摘要：

  Reactions of diethoxydimethylsilane with Schiff bases derived from the condensation of fur-furaldehyde, indole-3-carbaldehyde with alanine, glycine, valine, isoleucine and tryptophan in a 1:2 molar ratio give a new series of Me2Si ((N O) over cap)(2) type of organosilicon (IV) complexes. The complexes are monomeric and non-electrolytic in nature. The coordination behaviour of Schiff bases through organosilicon (IV) has been investigated by IR, H-1, C-13 & Si-29 NMR spectral studies. Schiff bases and their silicon complexes have also been screened for their antifungal activity. Several of these complexes were found to be quite active in this respect.

  DOI：

  10.1080/10426500108040248
• 作为产物：
  描述：

  糠醛 、 聚甘氨酸 以 乙醇 为溶剂， 反应 5.0h， 生成 2-(2-呋喃基亚甲基氨基)乙酸
  参考文献：
  名称：

  COORDINATION BEHAVIOR OF BIOLOGICALLY ACTIVE SCHIFF BASES OF AMINO ACIDS TOWARDS SILICON(IV) ION

  摘要：

  Reactions of diethoxydimethylsilane with Schiff bases derived from the condensation of fur-furaldehyde, indole-3-carbaldehyde with alanine, glycine, valine, isoleucine and tryptophan in a 1:2 molar ratio give a new series of Me2Si ((N O) over cap)(2) type of organosilicon (IV) complexes. The complexes are monomeric and non-electrolytic in nature. The coordination behaviour of Schiff bases through organosilicon (IV) has been investigated by IR, H-1, C-13 & Si-29 NMR spectral studies. Schiff bases and their silicon complexes have also been screened for their antifungal activity. Several of these complexes were found to be quite active in this respect.

  DOI：

  10.1080/10426500108040248

文献信息

• Shukla, P. R.; Pandey, O. P.; Narain, Gopal, Journal of the Indian Chemical Society, <hi>1983</hi>, vol. 60, p. 397 - 399
  作者：Shukla, P. R.、Pandey, O. P.、Narain, Gopal

  DOI：——

  日期：——
• COORDINATION BEHAVIOR OF BIOLOGICALLY ACTIVE SCHIFF BASES OF AMINO ACIDS TOWARDS SILICON(IV) ION
  作者：M. Sharma、B. Khungar、S. Varshney、H. L. Singh、U. D. Tripaathi、A. K. Varshney

  DOI：10.1080/10426500108040248

  日期：2001.8.1

  Reactions of diethoxydimethylsilane with Schiff bases derived from the condensation of fur-furaldehyde, indole-3-carbaldehyde with alanine, glycine, valine, isoleucine and tryptophan in a 1:2 molar ratio give a new series of Me2Si ((N O) over cap)(2) type of organosilicon (IV) complexes. The complexes are monomeric and non-electrolytic in nature. The coordination behaviour of Schiff bases through organosilicon (IV) has been investigated by IR, H-1, C-13 & Si-29 NMR spectral studies. Schiff bases and their silicon complexes have also been screened for their antifungal activity. Several of these complexes were found to be quite active in this respect.