Lithiumgla

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Lithiumgla
• 英文别名: lithium;(6Z,9Z,12Z)-octadeca-6,9,12-trienoate
• 化学式: C18H29LiO2
• 分子量: 284.4
• InChiKey: VZHSEMJXKJCMSX-HPFCUAHCSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.33
• 重原子数：
  21
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Soft tissue implants and anti-scarring agents
  申请人：Hunter L. William

  公开号：US20050142162A1

  公开（公告）日：2005-06-30

  Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.

  软组织植入物（例如乳房、胸肌、下巴、面部、唇部和鼻部植入物）与抗瘢痕剂结合使用，以抑制动物体内植入物放置时可能发生的瘢痕形成。
• Silk stent grafts
  申请人：Angiotech International AG

  公开号：US20040199241A1

  公开（公告）日：2004-10-07

  Silk-containing stent grafts are provided comprising an endoluminal stent and a graft, wherein the silk is induces the in vivo adhesion of the stent graft to vessel walls, or, otherwise induces or accelerates an in vivo fibrotic reaction causing said stent graft to adhere to vessel wall. Also provided are methods for making and using such stent grafts.

  提供了含蚕丝的支架移植物，包括腔内支架和移植物，其中蚕丝可诱导支架移植物在体内粘附到血管壁上，或以其他方式诱导或加速体内纤维化反应，使所述支架移植物粘附到血管壁上。此外，还提供了制造和使用这种支架移植物的方法。
• Polymer compositions and methods for their use
  申请人：Hunter L. William

  公开号：US20050175665A1

  公开（公告）日：2005-08-11

  Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.

  包含抗纤维化剂和/或聚合物的组合物可用于各种医疗应用，包括预防手术粘连、治疗炎症性关节炎、治疗疤痕和瘢痕疙瘩、治疗血管疾病以及预防软骨流失。
• Electrical devices and anti-scarring agents
  申请人：Hunter L. William

  公开号：US20050182450A1

  公开（公告）日：2005-08-18

  Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the devices are implanted within an animal.

  用于与组织接触的电气设备（如心律管理和神经刺激设备）与抗疤痕剂（如细胞周期抑制剂）结合使用，以抑制设备植入动物体内时可能产生的疤痕。
• Implantable sensors and implantable pumps and anti-scarring agents
  申请人：Hunter L. William

  公开号：US20050186239A1

  公开（公告）日：2005-08-25

  Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal.

  用于与组织接触的泵和传感器与抗疤痕剂（如细胞周期抑制剂）结合使用，以抑制在动物体内植入泵和传感器时可能出现的疤痕。