(2S,3S)-2-formamido-3-[[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl]-2-(2-methylpropyl)tetradecanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (2S,3S)-2-formamido-3-[[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl]-2-(2-methylpropyl)tetradecanoic acid
• 化学式: C₂₉H₅₃NO₅
• 分子量: 495.7
• InChiKey: ZMQKCPDWSKLDSQ-VZTVMPNDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.8
• 重原子数：
  35
• 可旋转键数：
  22
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  92.7
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• TREATMENT OF UTERINE LEIOMYOMATA
  申请人：MORTON CYNTHIA C.

  公开号：US20140378388A1

  公开（公告）日：2014-12-25

  Embodiments herein provide a therapy for uterine leiomyomata (UL) in women using a fatty acid synthase (FAS) inhibitor. Additionally, an analysis method for evaluating the likelihood of women developing UL during their lifetime is provided.
• METHOD FOR SYNTHESIS OF FATTY ACIDS
  申请人：INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE

  公开号：US20170268027A1

  公开（公告）日：2017-09-21

  Disclosed is a method for synthesis of fatty acids by culturing a eukaryotic microorganism from the fungi kingdom, that is naturally oleaginous or rendered oleaginous. The culture is performed in the presence a fatty acid synthase inhibitor in the culture medium.