(N,N-dibutylcarbamoylmethyl)diphenylphosphine oxide | 80413-41-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (N,N-dibutylcarbamoylmethyl)diphenylphosphine oxide
• 英文别名: Acetamide, N,N-dibutyl-2-(diphenylphosphinyl)-；N,N-dibutyl-2-diphenylphosphorylacetamide
• CAS: 80413-41-8
• 化学式: C₂₂H₃₀NO₂P
• 分子量: 371.459
• InChiKey: SSPJHMCMDDKVPU-UHFFFAOYSA-N

物化性质

• 沸点：
  491.2±28.0 °C(Predicted)
• 密度：
  1.08±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  26
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  uranyl(VI) nitrate 、 (N,N-dibutylcarbamoylmethyl)diphenylphosphine oxide 以 氯仿 、 水 为溶剂， 以73.2%的产率得到
  参考文献：
  名称：

  Oxides of dialkyl(diaryl)[dialkylcarbamoylmethyl]phosphines

  摘要：

  DOI：

  10.1007/bf00949488
• 作为产物：
  描述：

  羧甲基二苯基氧膦 、 三(二丁基氨基)膦 以79%的产率得到(N,N-dibutylcarbamoylmethyl)diphenylphosphine oxide
  参考文献：
  名称：

  Turanov; Karandashev; Kharitonov, Russian Journal of General Chemistry, 1999, vol. 69, # 7, p. 1068 - 1074

  摘要：

  DOI：

文献信息

• A novel facile synthesis of carbamoylmethylphosphine oxides in ionic liquids
  作者：Elena V. Sharova、Oleg I. Artyushin、Alexander S. Shaplov、Galina V. Myasoedova、Irina L. Odinets

  DOI：10.1016/j.tetlet.2008.01.007

  日期：2008.3

  carbamoylmethylphosphine oxides (CMPO) in up to 96% isolated yield is developed via direct amidation of diphenylphosphoryl acetic acid in an ionic liquid as a recyclable reaction medium in the presence of triphenyl phosphite. The influence of the nature of the amine and anion and cation structure in the ionic liquid on the reaction rate and yields of the products are also investigated. 1-Butyl-3-methylimidazolium

  在亚磷酸三苯酯存在下，通过在离子液体中直接酰胺化二苯基磷酰基乙酸作为可循环的反应介质，可以方便地获得高达96％分离产率的氨基甲酰基甲基氧化膦（CMPO）。还研究了离子液体中胺，阴离子和阳离子结构的性质对反应速率和产物收率的影响。事实证明1-溴-3-甲基咪唑鎓溴化[bmim] Br和三己基十四烷基氯化phosph [P（C 6 H 13）3（C 14 H 29）] Cl是进行该反应的最佳介质。
• Complexation of N-alkyl(aryl)- and N,N-dialkylcarbamoylmethylphosphine oxides with the f-elements
  作者：E. V. Sharova、O. I. Artyushin、Yu. V. Nelyubina、K. A. Lyssenko、M. P. Passechnik、I. L. Odinets

  DOI：10.1007/s11172-008-0255-9

  日期：2008.9

  Complexation of N-alkyl(aryl)carbamoylmethylphosphine oxides (CMPO) and their N, N-dialkyl analogs in neutral media was studied. N-Alkyl derivatives react with praseodymium and europium nitrates both in solution and in the individual state to give 1: 2 and 1: 3 complexes, depending on the ratio of the starting reagents; for N-aryl amides, 1: 3 complexes were obtained only. With the uranyl cation, both

  研究了 N-烷基（芳基）氨基甲酰基甲基氧化膦 (CMPO) 及其 N，N-二烷基类似物在中性介质中的络合。N-烷基衍生物与溶液中和单独状态下的镨和铕硝酸盐反应，生成 1:2 和 1:3 的配合物，具体取决于起始试剂的比例；对于 N-芳基酰胺，仅获得 1:3 的配合物。与铀酰阳离子一起，CMPO 的 N-烷基和 N,N-二烷基衍生物形成各种 1:1 配合物。
• Study of thermochemical properties of diphenyl[dialkyl(alkyl)carbamoylmethyl]phosphine oxides
  作者：B. I. Petrov、G. A. Abakumov、A. V. Arapova、E. V. Sharova、O. I. Artiushin、I. L. Odinets、N. M. Lazarev、Yu. A. Bessonova

  DOI：10.1134/s107036321111003x

  日期：2011.11

  The synthesis and the studies of properties of diphenyl[dialkyl(alkyl)carbamoylmethyl]phosphine oxides by differential scanning calorimetry, mass spectrometry and Knudsen effusion method were performed. The thermodynamic parameters of melting and vaporization were calculated.
• Basicity and conformational analysis of carbamoylmethylphosphoryl compounds
  作者：E. I. Matrosov、A. P. Baranov、A. G. Matveeva、N. P. Nesterova、M. I. Kabachnik

  DOI：10.1007/bf00961352

  日期：1991.5

  The basicity in nitromethane of carbamoylmethylphosphoryl compounds (CMP), RR' P(O)CHR''' C(O)NR2", containing different substituents at the phosphorus or nitrogen atoms and in the methylene bridge and binary reactants (CMP)2X, where X = (CH2)5 or p-CH2C6H4CH2, was investigated. The values of pK(a) are linearly correlated with SIGMA-sigma-P, the constant of the substituents at the phosphorus atom. Conformational analysis of CMP and tetraphenylmethylenediphosphine dioxides substituted in the methylene bridge showed that bulky substituents reduce the population of complexing conformations.
• Kulyako, Yu. M.; Samsonov, M. D.; Litvina, M. N., Radiochemistry, 2002, vol. 44, p. 255 - 260
  作者：Kulyako, Yu. M.、Samsonov, M. D.、Litvina, M. N.、Chmutova, M. K.、Myasoyedov, B. F.

  DOI：——

  日期：——