6,7-dimethoxy-anthracene-2,3-dicarbonitrile | 1134642-49-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 6,7-dimethoxy-anthracene-2,3-dicarbonitrile
• 英文别名: 6,7-Dimethoxyanthracene-2,3-dicarbonitrile；6,7-dimethoxyanthracene-2,3-dicarbonitrile
• CAS: 1134642-49-1
• 化学式: C₁₈H₁₂N₂O₂
• 分子量: 288.305
• InChiKey: QBUJGLZYAQVFAY-UHFFFAOYSA-N

物化性质

• 沸点：
  547.0±50.0 °C(Predicted)
• 密度：
  1.30±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  66
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  6,7-dimethoxy-naphthalene-2,3-dicarbaldehyde 、 反丁烯二腈 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 三乙基膦 作用下， 以 二氯甲烷 为溶剂， 以49%的产率得到6,7-dimethoxy-anthracene-2,3-dicarbonitrile
  参考文献：
  名称：

  Iterative synthesis of acenesvia homo-elongation

  摘要：

  从芳香邻二醛出发，我们设计了一套同系延长方案，结合了Wittig烯化反应和随后的分子内Knoevenagel缩合反应，以生成并五烷二酯和二腈。

  DOI：

  10.1039/b814840f

文献信息

• Nanoparticulate probe for in vivo monitoring of tissue oxygenation
  申请人：Kupussamy Periannan

  公开号：US20070041909A1

  公开（公告）日：2007-02-22

  A new class of micro- and nano-particulate paramagnetic spin probes useful for magnetic resonance imaging techniques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI). The probes are lithium phthalocyanine derivative compounds. Also provided are suspensions and emulsions comprising lithium phthalocyanine derivative probes. Also provided are noninvasive methods for measuring noninvasive methods of measuring oxygen concentration, oxygen partial pressure, oxygen metabolism, and nitric oxide concentration in a specific tissue, organ, or cell in vivo or in vitro.
• NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION
  申请人：The Ohio State University Research Foundation

  公开号：US20140170073A1

  公开（公告）日：2014-06-19

  A new class of micro- and nano-particulate paramagnetic spin probes especially useful for magnetic resonance imaging techniques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI). The probes are lithium phthalocyanine derivative compounds. Also provided are suspensions and emulsions comprising lithium phthalocyanine derivative probes. Also provided are noninvasive methods for measuring noninvasive methods of measuring oxygen concentration, oxygen partial pressure, oxygen metabolism, and nitric oxide concentration in a specific tissue, organ, or cell in vivo or in vitro.
• US8066973B2
  申请人：——

  公开号：US8066973B2

  公开（公告）日：2011-11-29
• Iterative synthesis of acenesvia homo-elongation
  作者：Chih-Hsiu Lin、Ke-Han Lin、Bikash Pal、Li-Der Tsou

  DOI：10.1039/b814840f

  日期：——

  Starting from aromaticortho-dialdehydes, we devised a homo-elongation protocol that combines a Wittig olefination and subsequent intramolecular Knoevenagel condensation to produce acene diesters and dinitriles.

  从芳香邻二醛出发，我们设计了一套同系延长方案，结合了Wittig烯化反应和随后的分子内Knoevenagel缩合反应，以生成并五烷二酯和二腈。