4-[(E)-2-(2-thienyl)ethenyl][1,3,5]triazino[1,2-a]benzimidazol-2-amine | 1060549-00-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 4-[(E)-2-(2-thienyl)ethenyl][1,3,5]triazino[1,2-a]benzimidazol-2-amine
• 英文别名: (E)-4-(2-(thiophen-2-yl)vinyl)benzo[4,5]imidazo[1,2-a][1,3,5]triazin-2-amine；4-[(E)-2-(thiophen-2-yl)ethenyl][1,3,5]triazino[1,2-a]benzimidazol-2-amine；4-[(E)-2-thiophen-2-ylethenyl]-[1,3,5]triazino[1,2-a]benzimidazol-2-amine
• CAS: 1060549-00-9
• 化学式: C₁₅H₁₁N₅S
• 分子量: 293.352
• InChiKey: VREKGQOLKGHWAD-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  97.3
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-[2-(2-噻吩基)乙烯基]-4-氧代-1,3-苯并恶嗪高氯酸盐 、 2-胍基苯并咪唑 在 sodium 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以28%的产率得到4-[(E)-2-(2-thienyl)ethenyl][1,3,5]triazino[1,2-a]benzimidazol-2-amine
  参考文献：
  名称：

  Reactions of 4-oxo-1,3-benzoxazinium perchlorates with guanidines

  摘要：

  Condensation of 2-methyl-4-oxo-1,3-benzoxazinium perchlorate with various aromatic and heterocyclic aldehydes provided previously unknown arylvinyl- and hetarylvinyl-substituted salts whose recyclization under treatment with guanidine resulted in formerly undescribed 1,3,5-triazines. The reaction of perchlorates obtained with guanidinebenzoxazole led to the formation of bishetarylamines, with guanidinebenzimidazole formed triazinebenzimidazoles, the cyanoguanidine reacted with 4-oxo-1,3-benzoxazinium perchlorates to give cyanamides.

  DOI：

  10.1134/s1070428007100259

文献信息

• Reactions of 4-oxo-1,3-benzoxazinium perchlorates with guanidines
  作者：E. Yu. Suvorova、N. I. Vikrishchuk、L. D. Popov、Z. A. Starikova、A. D. Vikrishchuk、Yu. A. Zhdanov

  DOI：10.1134/s1070428007100259

  日期：2007.10

  Condensation of 2-methyl-4-oxo-1,3-benzoxazinium perchlorate with various aromatic and heterocyclic aldehydes provided previously unknown arylvinyl- and hetarylvinyl-substituted salts whose recyclization under treatment with guanidine resulted in formerly undescribed 1,3,5-triazines. The reaction of perchlorates obtained with guanidinebenzoxazole led to the formation of bishetarylamines, with guanidinebenzimidazole formed triazinebenzimidazoles, the cyanoguanidine reacted with 4-oxo-1,3-benzoxazinium perchlorates to give cyanamides.