(Z)-hex-3-enoyl chloride | 97253-82-2

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: (Z)-hex-3-enoyl chloride
• 英文别名: (z)-3-Hexenoyl chloride
• CAS: 97253-82-2
• 化学式: C₆H₉ClO
• 分子量: 132.59
• InChiKey: BSUODTDYSTUDAV-ARJAWSKDSA-N

物化性质

• 沸点：
  52 °C(Press: 28 Torr)
• 密度：
  1.022±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (Z)-hex-3-enoyl chloride 在 三乙胺 作用下， 生成 (Z)-4-bromo-2-(1,3-dithian-2-yl)phenyl hex-3-enoate
  参考文献：
  名称：

  ACYLOXY SUBSTITUTED PHENYL DITHIANE DERIVATIVES

  摘要：

  Para-酰基取代的二氮杂环己烯，其医药配方和制备和使用方法。

  公开号：

  US20220235024A1
• 作为产物：
  描述：

  顺式-3-己烯酸 在 草酰氯 作用下， 以 苯 为溶剂， 反应 2.0h， 生成 (Z)-hex-3-enoyl chloride
  参考文献：
  名称：

  Multifunctional communication inRiptortus clavatus (Heteroptera: Alydidae): Conspecific nymphs and egg parasitoidOoencyrtus nezarae use the same adult attractant pheromone as chemical cue

  摘要：

  The bean bug, Riptortus clavatus lays scattered eggs (as opposed to the egg masses of pentatomids) on host as well as nonhost plants. Therefore, the first feeding stage (second-instar) nymphs emerging from eggs laid on nonhost plants need a signal that enables them to locate a food source at the lowest energy cost. Male-released (E)-2-hexenyl (E)-2-hexenoate, (E)-2-hexenyl (Z)-3-hexenoate, and myristyl isobutyrate play the double role of attractant pheromone for adults as well as aggregation pheromone, which enables the second-instar nymphs to find the host food plant. These male-specific semiochemicals are released only when foodstuff is available. On the other hand, females of Ooencyrtus nezarae, the most effective parasitoid of the host in Kumamoto, Japan (where the field experiments were conducted), utilize these semiochemicals as kairomones in order to locate the potential host community. Field experiments revealed that the synthetic pheromone rivaled 10 live males in the attraction of adults and second-instar nymphs. Captures of the egg parasitoid O. nezarae females in cylindrical sticky traps were significantly higher in traps baited with the synthetic semiochemicals than in control traps. The number of females captured was significantly higher than the number of males, although the captures in the sticky suction trap system revealed that the populations of male and female were not significantly different.

  DOI：

  10.1007/bf02033802

文献信息

• Syntheses of Methyl Jasmonate and Analogues
  作者：Christian Chapuis、David Skuy、Claude-Alain Richard

  DOI：10.2533/chimia.2019.194

  日期：——

  This account corresponds to the presentation given by the main author on the occasion of the 2nd Swiss Industrial Symposium in Basel (October 19th , 2018). After a short historical introduction to methyl-jasmonate and methyl-epijasmonate, it essentially focuses on the reported more promising industrial approaches devoted to the synthesis of these naturally occurring odorants isolated from jasmine flowers

  本报道与主要作者在巴塞尔第二届瑞士工业研讨会（2018 年 10 月 19 日）上的演讲相对应。在对茉莉酸甲酯和表茉莉酸甲酯进行简短的历史介绍后，它主要关注报道的更有前途的工业方法，致力于合成从茉莉花中分离出的这些天然存在的气味剂。还提出了一些简化这些方法的尝试，以及独立的未报告策略。还讨论了几种不对称方法，例如 Xie 氢化、Corey-CBS 还原、酶促拆分和 1,4-加成。
• FATTY ACID ACETYLATED SALICYLATES AND THEIR USES
  申请人：Milne Jill C.

  公开号：US20100041748A1

  公开（公告）日：2010-02-18

  The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a Fatty Acid Acetylated Salicylate Derivative.

  本发明涉及脂肪酸乙酰水杨酸衍生物；包含有效量的脂肪酸乙酰水杨酸衍生物的组合物；以及用于治疗或预防炎症性疾病的方法，包括给药有效量的脂肪酸乙酰水杨酸衍生物。
• NOVEL CERAMIDE DERIVATIVES HAVING AGONISTIC EFFECTS ON EPIDERMAL CANNABINOID RECEPTORS, AND PHARMACEUTICAL OR COSMETIC COMPOSITION CONTAINING SAME
  申请人：NEOPHARM CO., LTD.

  公开号：US20160272578A1

  公开（公告）日：2016-09-22

  The present invention relates to a novel pseudoceramide derivative, a pharmaceutically acceptable salt thereof or a solvate thereof, and a pharmaceutical or cosmetic composition containing the same as an active ingredient. The novel pseudoceramide derivative of the present invention is expected to be very useful for treating or preventing skin diseases by activating cannabinoid receptors. In addition, the novel pseudoceramide derivative, the pharmaceutically acceptable salt thereof or the solvate thereof, of the present invention, has a simple synthesis process compared with a known cannabinoid receptor antagonist so as to reduce processing time and curtail material costs, and thus is economical, and has advantages such as easy emulsification during the formulation of cosmetic products or medical supplies.

  本发明涉及一种新型的伪神经酰胺衍生物，其药学上可接受的盐或其溶剂，并且一种含有该衍生物作为活性成分的制药或化妆品组合物。本发明的新型伪神经酰胺衍生物通过激活大麻素受体，预计非常有用于治疗或预防皮肤疾病。此外，本发明的新型伪神经酰胺衍生物、其药学上可接受的盐或其溶剂与已知的大麻素受体拮抗剂相比，具有简单的合成过程，从而减少处理时间和材料成本，因此经济实惠，并具有易于在化妆品或医疗用品的制剂过程中乳化的优点。
• Fatty Acid Acylated Salicylates and Their Uses
  申请人：Vu Chi B.

  公开号：US20100184730A1

  公开（公告）日：2010-07-22

  The invention relates to fatty acid acylated salicylate derivatives; compositions comprising an effective amount of a fatty acid acylated salicylate derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a fatty acid acylated salicylate derivative.

  本发明涉及脂肪酸酰化水杨酸衍生物，包括含有效量脂肪酸酰化水杨酸衍生物的组合物，以及治疗或预防炎症性疾病的方法，其中包括给予有效量的脂肪酸酰化水杨酸衍生物。
• FATTY ACID ACYLATED SALICYLATES AND THEIR USES
  申请人：Catabasis Pharmaceuticals, Inc.

  公开号：US20160083336A1

  公开（公告）日：2016-03-24

  The invention relates to fatty acid acylated salicylate derivatives; compositions comprising an effective amount of a fatty acid acylated salicylate derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a fatty acid acylated salicylate derivative.

  该发明涉及脂肪酸酰化水杨酸衍生物；包含有效量的脂肪酸酰化水杨酸衍生物的组合物；以及治疗或预防炎症性疾病的方法，其中包括给予有效量的脂肪酸酰化水杨酸衍生物的管理。