2-(4-溴-5-甲基-3-硝基-1-吡唑)乙酸 | 345637-67-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2-(4-溴-5-甲基-3-硝基-1-吡唑)乙酸
• 中文别名: (4-溴-5-甲基-3-硝基-吡唑-1-基)-乙酸；2-(4-溴-5-甲基-3-硝基-吡唑-1-基)乙酸；(4-溴-5-甲基-3-硝基-1H-吡唑-1-基)-乙酸
• 英文名称: (4-bromo-5-methyl-3-nitro-1H-pyrazol-1-yl)acetic acid
• 英文别名: 2-(4-bromo-5-methyl-3-nitropyrazol-1-yl)acetic acid
• CAS: 345637-67-4
• 化学式: C6H6BrN3O4
• mdl: MFCD00297272
• 分子量: 264.03
• InChiKey: JUGOZTZNWGFYHL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  101
• 氢给体数：
  1
• 氢受体数：
  5

安全信息

• 危险等级：
  IRRITANT
• 海关编码：
  2933199090

文献信息

• Hydralazine for use in the treatment of age-related macular degeneration
  申请人：THE TEXAS A&M UNIVERSITY SYSTEM

  公开号：EP2508182B1

  公开（公告）日：2016-07-06
• Interleukin-1 blocker for use in the treatment of age-related macular degeneration
  申请人：THE TEXAS A & M UNIVERSITY SYSTEM

  公开号：EP2508183B1

  公开（公告）日：2014-07-09
• Therapeutic Compositions And Methods
  申请人：Chiou George C.

  公开号：US20120071485A1

  公开（公告）日：2012-03-22

  The present invention relates in general to therapeutic compositions and methods of use. In preferred embodiments, the invention relates to the field of eye health. In some embodiments, the invention relates to the prevention and treatment of macular degeneration by administering compounds disclosed herein. In some embodiments, the invention relates to compositions and methods of improving vision.
• THERAPEUTIC COMPOSITIONS AND METHODS
  申请人：CHIOU GEORGE C.

  公开号：US20120196868A1

  公开（公告）日：2012-08-02

  The present invention relates in general to therapeutic compositions and methods of use. In preferred embodiments, the invention relates to the field of eye health. In some embodiments, the invention relates to the prevention and treatment of macular degeneration by administering compounds disclosed herein. In some embodiments, the invention relates to compositions and methods of improving vision.
• US8088773B2
  申请人：——

  公开号：US8088773B2

  公开（公告）日：2012-01-03