4-methyl-2-pentyl propionate | 98955-48-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-methyl-2-pentyl propionate
• 英文别名: propionic acid-(1,3-dimethyl-butyl ester)；Propionsaeure-(1,3-dimethyl-butylester)；4-Methylpentan-2-yl propanoate
• CAS: 98955-48-7
• 化学式: C₉H₁₈O₂
• 分子量: 158.241
• InChiKey: OHOHAFRZJYESCB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-甲基-2-戊酮 在 4-二甲氨基吡啶 、 sodium tetrahydroborate 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 0.17h， 生成 4-methyl-2-pentyl propionate
  参考文献：
  名称：

  Enzymatic kinetic resolution of aliphatic sec -alcohols by LipG9, a metagenomic lipase

  摘要：

  Bioprospection for new enantioselective enzymes for application in organic synthesis is a prominent area of investigation in biocatalysis. In this context, here we present the evaluation of an immobilized lipase isolated from a metagenomic library (LipG9) for the enzymatic kinetic resolution (EKR) of aliphatic sec -alcohols, which are still challenging substrates, since low enantioselectivity values are usually observed for these resolutions. LipG9 was successfully employed in EKR of aliphatic alcohols, which were resolved with satisfactory conversions (19-59%) and enantiomeric excesses for alcohols (26-88%) and esters (30-96%) by transesterification reactions, demonstrating that its performance is equal to or better than commercially available enzymes for the same reaction. (C) 2016 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcatb.2015.12.010

文献信息

• [EN] METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS<br/>[FR] PROCÉDÉS DE LUTTE CONTRE DES ORGANISMES NUISIBLES RÉSISTANT AUX NÉONICOTINOÏDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2014154488A1

  公开（公告）日：2014-10-02

  The present invention relates to a method of controlling insects (in particular insects of the order Hemiptera, especially aphids and whitefly) that are resistant to neonicotinoid insecticides, to methods of controlling insects whereby undesired insects are affected but beneficial arthropods are not affected, using compounds of formula (I) (where A, R1 and R2 are as defined above), and, further, to novel compounds of formula (I) which are useful in the aforementioned methods and/or which possess enhanced insecticidal properties, and to compositions containing said compounds.

  本发明涉及一种控制对新烟碱类杀虫剂产生抗性的昆虫（特别是半翅目昆虫，尤其是蚜虫和烟粉虱）的方法，以及控制昆虫的方法，通过影响不受欢迎的昆虫而不影响有益的节肢动物，使用式（I）化合物（其中A、R1和R2如上所定义），此外，还涉及式（I）的新化合物，这些化合物在上述方法中是有用的和/或具有增强的杀虫性能，并且含有所述化合物的组合物。
• Benzamidine derivatives
  申请人：SANKYO COMPANY, LIMITED

  公开号：US20040248981A1

  公开（公告）日：2004-12-09

  Benzamidine derivatives of formula (I) or pharmaceutically acceptable salts thereof exhibit excellent inhibitory activity against factor Xa and are useful for treating or preventing blood coagulation disorders: 1 wherein R 1 represents a hydrogen atom, a halogen atom, an alkyl group or a hydroxyl group; R 2 represents a hydrogen atom, a halogen atom or an alkyl group, R 3 represents a hydrogen atom, an optionally substituted alkyl group, an aralkyl group, an optionally substituted alkanoyl group or an optionally substituted alkylsulfonyl group, R 4 and R 5 are the same as or different from each other and each represent a hydrogen atom, a halogen atom, an optionally substituted alkyl group, an alkoxy group, a carboxyl-group, an alkoxycarbonyl group or an optionally substituted carbamoyl group, and R 6 represents a substituted pyrrolidine group or substituted piperidine group.

  公式（I）中的苯甲酰胺衍生物或其药学上可接受的盐表现出优异的抑制因子Xa的活性，可用于治疗或预防血液凝固障碍：其中R1代表氢原子，卤原子，烷基或羟基；R2代表氢原子，卤原子或烷基，R3代表氢原子，可选取代的烷基，芳基烷基，可选取代的烷酰基或可选取代的烷基磺酰基，R4和R5相同或不同，每个代表氢原子，卤原子，可选取代的烷基，烷氧基，羧基，烷氧羰基或可选取代的氨基甲酰基，而R6代表取代的吡咯烷基或取代的哌嗪烷基。
• METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：US20160050930A1

  公开（公告）日：2016-02-25

  The present invention relates to a method of controlling insects (in particular insects of the order Hemiptera, especially aphids and whitefly) that are resistant to neonicotinoid insecticides, to methods of controlling insects whereby undesired insects are affected but beneficial arthropods are not affected, using compounds of formula (I) (where A, R1 and R2 are as defined above), and, further, to novel compounds of formula (I) which are useful in the aforementioned methods and/or which possess enhanced insecticidal properties, and to compositions containing said compounds.

  本发明涉及一种控制昆虫（特别是半翅目昆虫，尤其是蚜虫和白粉虱）的方法，这些昆虫对新烟碱类杀虫剂具有抗性，以及控制昆虫的方法，其中不需要的昆虫受到影响，但有益的节肢动物不受影响，使用式（I）化合物（其中A、R1和R2如上所定义），以及式（I）的新型化合物，这些化合物在上述方法中是有用的和/或具有增强的杀虫性能，并且包含该化合物的组合物。
• BENZAMIDINE DERIVATIVES
  申请人：Sankyo Company, Limited

  公开号：EP1245564A1

  公开（公告）日：2002-10-02

  Benzamidine derivatives of formula (I) or pharmaceutically acceptable salts thereof exhibit excellent inhibitory activity against factor Xa and are useful for treating or preventing blood coagulation disorders: wherein R1 represents a hydrogen atom, a halogen atom, an alkyl group or a hydroxyl group; R2 represents a hydrogen atom, a halogen atom or an alkyl group, R3 represents a hydrogen atom, an optionally substituted alkyl group, an aralkyl group, an optionally substituted alkanoyl group or an optionally substituted alkylsulfonyl group, R4 and R5 are the same as or different from each other and each represent a hydrogen atom, a halogen atom, an optionally substituted alkyl group, an alkoxy group, a carboxyl group, an alkoxycarbonyl group or an optionally substituted carbamoyl group, and R6 represents a substituted pyrrolidine group or substituted piperidine group.

  式（I）的苯甲脒衍生物或其药学上可接受的盐类对 Xa 因子具有优异的抑制活性，可用于治疗或预防血液凝固紊乱： 其中 R1 代表氢原子、卤素原子、烷基或羟基；R2代表氢原子、卤素原子或烷基，R3代表氢原子、任选取代的烷基、芳烷基、任选取代的烷酰基或任选取代的烷磺酰基，R4和R5彼此相同或不同，各自代表氢原子、卤素原子、任选取代的烷基、烷氧基、羧基、烷氧羰基或任选取代的氨基甲酰基，R6代表取代的吡咯烷基或取代的哌啶基。
• Pyrolysis of Esters. VII. Influence of Acid Portion^1,2
  作者：WILLIAM J. BAILEY、JOHN J. HEWITT

  DOI：10.1021/jo01111a016

  日期：1956.5