3-[3-[3-[3-(3-Aminopropyl)phenyl]phenyl]phenyl]propan-1-amine | 1448256-83-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-[3-[3-[3-(3-Aminopropyl)phenyl]phenyl]phenyl]propan-1-amine
• 英文别名: 3-[3-[3-[3-(3-aminopropyl)phenyl]phenyl]phenyl]propan-1-amine
• CAS: 1448256-83-4
• 化学式: C₂₄H₂₈N₂
• 分子量: 344.5
• InChiKey: SKIGOKNHVUEJHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  26
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3,3'-([1,1':3',1''-terphenyl]-3,3''-diyl)dipropanenitrile 在 硼烷四氢呋喃络合物 作用下， 以 四氢呋喃 为溶剂， 以0.04 g的产率得到3-[3-[3-[3-(3-Aminopropyl)phenyl]phenyl]phenyl]propan-1-amine
  参考文献：
  名称：

  [EN] POLYCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME
  [FR] COMPOSÉS POLYCYCLIQUES ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION

  摘要：

  公开号：

  WO2014093225A3

文献信息

• Polymeric Compounds And Methods Of Making And Using The Same
  申请人：Fan Xiaodong

  公开号：US20140308317A1

  公开（公告）日：2014-10-16

  The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for inhibiting the growth of a microbe; treating a mammal having a microbial infection, malaria, mucositis, an ophthalmic infection, an otic infection, a cancer, or a Mycobacterium infection; killing or inhibiting the growth of a Plasmodium species; inhibiting the growth of a Mycobacterium species; modulating an immune response in a mammal; or antagonizing unfractionated heparin, low molecular weight heparin, or a heparin/low molecular weight heparin derivative.

  本公开提供化合物或其药学上可接受的盐，用于抑制微生物的生长；治疗患有微生物感染，疟疾，口腔炎，眼部感染，耳部感染，癌症或结核分枝杆菌感染的哺乳动物；杀死或抑制疟原虫的生长；抑制结核分枝杆菌的生长；调节哺乳动物的免疫反应；或拮抗非分散肝素，低分子量肝素或肝素/低分子量肝素衍生物。
• Compounds And Methods For Treating Candidiasis And Aspergillus Infections
  申请人：Scott Richard W.

  公开号：US20130252964A1

  公开（公告）日：2013-09-26

  The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for killing or inhibiting the growth of a Candida or Aspergillus species or preventing or treating a mammal having candidiasis (oral and/or disseminated) or an Aspergillus infection.
• COMPOUNDS AND METHODS FOR TREATING CANDIDIASIS AND ASPERGILLUS INFECTIONS
  申请人：Cellceutix Corporation

  公开号：US20160287586A1

  公开（公告）日：2016-10-06

  The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for killing or inhibiting the growth of a Candida or Aspergillus species or preventing or treating a mammal having candidiasis (oral and/or disseminated) or an Aspergillus infection.
• [EN] COMPOUNDS AND METHODS FOR TREATING CANDIDIASIS AND ASPERGILLUS INFECTIONS<br/>[FR] COMPOSÉS ET MÉTHODES PERMETTANT DE TRAITER CANDIDOSES ET INFECTIONS À ASPERGILLUS
  申请人：POLYMEDIX INC

  公开号：WO2013109827A1

  公开（公告）日：2013-07-25

  The present disclosure provides facially arnphiphilic antimicrobial oligomers, pharmaceutically acceptable salts thereof, or a pharmaceutical composition thereof, useful for killing or inhibiting the growth of a Candida or Aspergillus species, as well as preventing or treating a mammal having oral or disseminated candidiasis or an aspergillus infection. The method(s) employed comprise(s) contacting the Candida or Aspergillus species with or administering to the mammal in need thereof an effective amount of such an antimicrobial oligomer, pharmaceutically acceptable salts thereof, or a pharmaceutical composition thereof.
• [EN] POLYCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME<br/>[FR] COMPOSÉS POLYCYCLIQUES ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
  申请人：CELLCEUTIX CORP

  公开号：WO2014093225A3

  公开（公告）日：2014-08-07