(Z)-3-(4-diethylamino-phenylcarbamoyl)-acrylic acid | 1131006-80-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (Z)-3-(4-diethylamino-phenylcarbamoyl)-acrylic acid
• 英文别名: (Z)-4-[4-(diethylazaniumyl)anilino]-4-oxobut-2-enoate
• CAS: 1131006-80-8
• 化学式: C₁₄H₁₈N₂O₃
• mdl: MFCD01469703
• 分子量: 262.309
• InChiKey: YUMYXNLWGRTNRB-KTKRTIGZSA-N

物化性质

• 沸点：
  498.4±45.0 °C(Predicted)
• 密度：
  1?+-.0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  69.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  马来酸酐 、 N,N-二乙基对苯二胺 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 以28%的产率得到(Z)-3-(4-diethylamino-phenylcarbamoyl)-acrylic acid
  参考文献：
  名称：

  Synthesis and Copolymerization Study of New Polyimide Precursors with Potential Application in Optical and Photonic Field

  摘要：

  New polyimide precursors were synthesized by simple one step procedure. (Z)-3-(4-Nitro-phenylcarbamoyl)-acrylic acid (A2), (Z)-3-(4-Ciano-phenylcarbamoyl)acrylic acid (A3), (Z)-3-(4-Diethyl-phenylcarbamoyl)-acrylic acid (A4) and (Z)-3-[N'-(2,4-Dinitro-phenyl)-hydrazinocarbonyl]-acrylic acid (A6) were characterized by FT-IR, FT-NMR and UV-VIS spectroscopy. Test copolymerization successfully yielded copolymers that were characterized by FT-IR and FT-NMR spectroscopy. Improved solubility of these copolymers make them candidates for potential NLO applications.

  DOI：

  10.1080/15421400801917338

文献信息

• [EN] PHTHALANILATE COMPOUNDS AND METHODS OF USE<br/>[FR] COMPOSÉS DE PHTALANILATE ET LEURS PROCÉDÉS D'UTILISATION
  申请人：UNIV NOTRE DAME DU LAC

  公开号：WO2011026107A1

  公开（公告）日：2011-03-03

  The invention provides antimicrobial compounds and compositions, and methods of using them. The compounds and compositions include, for example, a compound of any one of Formulas I-X. The invention further provides methods of preparing the compounds, and useful intermediates for their preparation. The compounds can possess highly specific and selective activity, such as antibacterial activity and/or enzymatic inhibitory activity. Accordingly, the compounds and compositions can be used to treat bacterial infections, or to inhibit or kill bacteria, either in vitro or in vivo.

  本发明提供了抗微生物化合物和组合物，以及使用它们的方法。这些化合物和组合物包括，例如，I-X公式中的任何一种化合物。本发明进一步提供了制备这些化合物的方法，并提供了有用的中间体。这些化合物可以具有高度特异性和选择性活性，例如抗菌活性和/或酶抑制活性。因此，这些化合物和组合物可以用于治疗细菌感染，或者在体外或体内抑制或杀死细菌。
• PHTHALANILATE COMPOUNDS AND METHODS OF USE
  申请人：Mobashery Shahriar

  公开号：US20120232150A1

  公开（公告）日：2012-09-13

  The invention provides antimicrobial compounds and compositions, and methods of using them. The compounds and compositions include, for example, a compound of any one of Formulas I-X. The invention further provides methods of preparing the compounds, and useful intermediates for their preparation. The compounds can possess highly specific and selective activity, such as antibacterial activity and/or enzymatic inhibitory activity. Accordingly, the compounds and compositions can be used to treat bacterial infections, or to inhibit or kill bacteria, either in vitro or in vivo.
• US8859620B2
  申请人：——

  公开号：US8859620B2

  公开（公告）日：2014-10-14
• Synthesis and Copolymerization Study of New Polyimide Precursors with Potential Application in Optical and Photonic Field
  作者：Adriana Florica Nicolescu、Victor Valentin Jerca、Ana-Maria Albu、Dumitru Mircea Vuluga、Constantin Draghici

  DOI：10.1080/15421400801917338

  日期：2008.4.17

  New polyimide precursors were synthesized by simple one step procedure. (Z)-3-(4-Nitro-phenylcarbamoyl)-acrylic acid (A2), (Z)-3-(4-Ciano-phenylcarbamoyl)acrylic acid (A3), (Z)-3-(4-Diethyl-phenylcarbamoyl)-acrylic acid (A4) and (Z)-3-[N'-(2,4-Dinitro-phenyl)-hydrazinocarbonyl]-acrylic acid (A6) were characterized by FT-IR, FT-NMR and UV-VIS spectroscopy. Test copolymerization successfully yielded copolymers that were characterized by FT-IR and FT-NMR spectroscopy. Improved solubility of these copolymers make them candidates for potential NLO applications.