N-Anilino-N'-phenyl-guanidin | 4556-21-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-Anilino-N'-phenyl-guanidin
• 英文别名: 1-Anilino-2-phenylguanidine
• CAS: 4556-21-2
• 化学式: C₁₃H₁₄N₄
• 分子量: 226.281
• InChiKey: YDSNPZWNIXJHJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  62.4
• 氢给体数：
  3
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  原甲酸三甲酯 、 N-Anilino-N'-phenyl-guanidin 以156 mg的产率得到N-phenyl-1-phenyl-3-amino-1H-1,2,4-triazole
  参考文献：
  名称：

  Efficient Methodology for the Synthesis of 3-Amino-1,2,4-triazoles

  摘要：

  A general and efficient method for the preparation of 3-amino-1,2,4-triazoles has been developed. The desired 3-amino-1,2,4-triazoles (1) were prepared in good overall yield via two convergent routes. The key intermediate within both routes is substituted hydrazinecarboximidamide derivative 2.

  DOI：

  10.1021/jo9016502
• 作为产物：
  描述：

  1,4-Diphenyl-1,4-dihydro-3,6-diacetyl-1,2,4,5-tetrazin 在 乙醇 、 sodium ethanolate 作用下， 以 乙醇 为溶剂， 反应 20.0h， 生成 N-Anilino-N'-phenyl-guanidin
  参考文献：
  名称：

  Huisgen,R. et al., Chemische Berichte, 1965, vol. 98, p. 1476 - 1486

  摘要：

  DOI：

文献信息

• Rubber composition
  申请人：BRIDGESTONE CORPORATION, OTSUKA CHEMICAL CO., LTD.

  公开号：US20030134947A1

  公开（公告）日：2003-07-17

  Provided is a rubber composition comprising 100 parts by weight of a rubber component comprising at least one selected from the group consisting of natural rubber and synthetic rubbers and 0.05 to 20 parts by weight of at least one selected from compounds (A) represented by the following Formula (I): 1 wherein A 1 and A 2 each represent R—, R—NH—, R—X—NH—, R—NH—NH— or R—X—NH—NH—, and A 1 and A 2 may be the same or different; R represents any one of a hydrogen atom, an alkyl group having 1 to 18 carbon atoms which may be branched, a cycloalkyl group, an aryl group, an alkylaryl group or an alkenyl group, each group of which may include at least one substituent containing a sulfur atom, a nitrogen atom and an oxygen atom, and two R's may be combined in a molecule to form a ring containing a >C═NH bond; and X represents any one of those shown below: 2

  提供的是一种橡胶组合物，包括100份重量的橡胶组分，其中至少包括天然橡胶和合成橡胶中的一种，并且还包括0.05至20份重量的至少一种选择自以下式(I)所表示的化合物(A)：1其中，A1和A2分别表示R—，R—NH—，R—X—NH—，R—NH—NH—或R—X—NH—NH—，且A1和A2可以相同也可以不同；R表示氢原子、含有1至18个碳原子的烷基，可以是支链的，环烷基，芳基，烷基芳基或烯基，每个基中都可以包含至少一个含有硫原子、氮原子和氧原子的取代基，两个R可以结合在分子中形成一个含有>C═NH键的环；X表示下列任意一种：2
• Heat ageing resistant rubber composition
  申请人：Bridgestone Corporation

  公开号：EP1101793A1

  公开（公告）日：2001-05-23

  Provided is a rubber composition comprising 100 parts by weight of a rubber component comprising at least one selected from the group consisting of natural rubber and synthetic rubbers and 0.05 to 20 parts by weight of at least one selected from compounds (A) represented by the following Formula (I): wherein A1 and A2 each represent R-, R-NH-, R-X-NH-, R-NH-NH- or R-X-NH-NH-, and A1 and A2 may be the same or different; R represents any one of a hydrogen atom, an alkyl group having 1 to 18 carbon atoms which may be branched, a cycloalkyl group, an aryl group, an alkylaryl group or an alkenyl group, each group of which may include at least one substituent containing a sulfur atom, a nitrogen atom and an oxygen atom, and two R's may be combined in a molecule to form a ring containing a >C=NH bond; and X represents any one of those shown below:

  本发明提供了一种橡胶组合物，该组合物包含按重量计 100 份的橡胶成分，其中至少包含一种选自天然橡胶和合成橡胶组成的组的橡胶成分，以及按重量计 0.05 至 20 份的至少一种选自下式 (I) 所代表化合物 (A) 的橡胶成分： 其中 A1 和 A2 各自代表 R-、R-NH-、R-X-NH-、R-NH-NH- 或 R-X-NH-NH-，A1 和 A2 可以相同或不同；R 代表氢原子、具有 1 至 18 个碳原子且可以是支链的烷基、环烷基、芳基、烷芳基或烯基的任一种，其中每个基团可包括至少一个含有硫原子、氮原子和氧原子的取代基，两个 R 可在分子中结合形成一个含有 >C=NH 键的环；X 代表下表中的任一种：
• US6515055B1
  申请人：——

  公开号：US6515055B1

  公开（公告）日：2003-02-04
• US6667356B2
  申请人：——

  公开号：US6667356B2

  公开（公告）日：2003-12-23
• Efficient Methodology for the Synthesis of 3-Amino-1,2,4-triazoles
  作者：Romain Noël、Xinyi Song、Rong Jiang、Michael J. Chalmers、Patrick R. Griffin、Theodore M. Kamenecka

  DOI：10.1021/jo9016502

  日期：2009.10.2

  A general and efficient method for the preparation of 3-amino-1,2,4-triazoles has been developed. The desired 3-amino-1,2,4-triazoles (1) were prepared in good overall yield via two convergent routes. The key intermediate within both routes is substituted hydrazinecarboximidamide derivative 2.