1-Amino-3-(cyanoacetylamino)-4-nitrobenzene | 40828-20-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Amino-3-(cyanoacetylamino)-4-nitrobenzene
• 英文别名: 1-amino-3-cyanoacetylamino-4-nitrobenzene；N-(5-amino-2-nitrophenyl)-2-cyanoacetamide
• CAS: 40828-20-4
• 化学式: C₉H₈N₄O₃
• 分子量: 220.188
• InChiKey: LQVGEDHURHAKIN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  125
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  吉非替尼中间体3 、 对硝基间苯二胺 在 溶剂黄146 作用下， 以 苯 为溶剂， 反应 4.0h， 生成 1-Amino-3-(cyanoacetylamino)-4-nitrobenzene
  参考文献：
  名称：

  Diamino-nitro-benzene compounds

  摘要：

  一种染发制剂包含二氨基硝基苯化合物作为直接染发剂或包含二氨基硝基苯化合物作为偶联组分与氧化染料的显色组分相结合。一种染发人发的方法包括将这些制剂之一涂抹到头发上。

  公开号：

  US03933886A1

文献信息

• Neue Entwicklerkomponenten für Oxidationshaarfarben, deren Herstellung sowie diese enthaltende Haarfärbemittel
  申请人：Henkel Kommanditgesellschaft auf Aktien

  公开号：EP0011843A2

  公开（公告）日：1980-06-11

  Bis-(2,5-diaminophenoxy)alkane, deren Herstellung sowie Verwendung als Entwicklerkomponenten in Oxidationshaarfarben.

  双（2,5-二氨基苯氧基）烷烃，其制备方法以及在氧化染发剂中作为显影剂成分的用途。
• Dye composition for keratinous fiber
  申请人：Kao Corporation

  公开号：EP0299497A2

  公开（公告）日：1989-01-18

  A dye composition for keratinous fibers comprising a specific type of trifluoromethylated aniline derivative, as a developer, and a coupling substance is disclosed. The composition provides high degree of saturation and vividness of colors as well as good fastness. Dyeing with the use of the dye composition ensures a variety of developer - ­coupling agent combinations, which can provide a wide variety of colors with a high degree of color saturation and vividness. The color produced possesses excellent light resistance, washing resistance, and wear resistance. Amoung the trifluoromethylated aniline derivative, used as a developer, a p-phenylenediamine-type trifluoromethylated aniline derivative of the following formula is a novel compound. in which X represents a specific type of mono- or polyhydroxyalkyl group, alkyl group, or other organic group.

  本发明公开了一种用于角质纤维的染料组合物，该组合物包含一种特定类型的三氟甲基化苯胺衍生物（作为显影剂）和一种偶联物质。该组合物具有较高的色彩饱和度和鲜艳度以及良好的牢度。使用该染料组合物进行染色时，可确保多种显影剂-偶联剂组合，从而提供具有高色彩饱和度和鲜艳度的多种颜色。生产出的颜色具有出色的耐光性、耐洗性和耐磨性。在用作显影剂的三氟甲基苯胺衍生物中，下式所示的对苯二胺型三氟甲基苯胺衍生物是一种新型化合物。 其中 X 代表特定类型的单羟基或多羟基烷基、烷基或其他有机基团。
• Dye composition for keratinous fibers
  申请人：KAO CORPORATION

  公开号：EP0441263A1

  公开（公告）日：1991-08-14

  A dye composition for keratinous fibers is discosed. The composition comprises a developing substance and, as a coupling substance, a 3,5-diaminopyridine derivative of the following formula (I), wherein R¹ is an alkoxy group or a group wherein R² and R³ may be the same or different and individually represents a hydrogen atom or a hydroxyalkyl group, R⁴ a hydroxy, alkoxy, or hydroxyalkyl group, and n is a number of 1-4; or a salt thereof. The composition is capable of dyeing keratinous fibers such as hairs in blue color with a high vividness and with resistances to the light, color change, and discoloration due to shampooing.

  本发明公开了一种用于角质纤维的染料组合物。该组合物包括显影物质和作为偶联物质的下式（I）的 3,5-二氨基吡啶衍生物、 其中 R¹ 是烷氧基或基团 其中 R² 和 R³ 可以相同或不同，各自代表氢原子或羟烷基，R⁴ 是羟基、烷氧基或羟烷基，n 是 1-4 的数字；或其盐。该组合物能够将毛发等角质纤维染成鲜艳的蓝色，并具有耐光性、耐色变性和耐洗发变色性。
• Dyeing composition for keratin fiber
  申请人：Kao Corporation

  公开号：EP0455168A1

  公开（公告）日：1991-11-06

  A dyeing composition for a keratin fiber which comprises 1,5-dihydroxynaphthalene as a coupling substance, 2-amino-5-hydroxybenzoic acid or a cosmetically acceptable salt thereof as a color developing substance, and a cosmetically acceptable base is disclosed. The dyeing composition for a keratin fiber give a vivid red color tone having a high chroma and an extremely high fastness.

  本发明公开了一种用于角质纤维的染色组合物，该组合物由作为偶联物质的 1,5-二羟基萘、作为显色物质的 2-氨基-5-羟基苯甲酸或其化妆品可接受盐以及化妆品可接受基质组成。这种用于角蛋白纤维的染色组合物能染出鲜艳的红色，色度高，牢度极高。
• 2-Alkoxy-3,5-diaminopyridine derivatives and their salts, and dye compositions for keratinous fibers containing them
  申请人：KAO CORPORATION

  公开号：EP0559217A1

  公开（公告）日：1993-09-08

  A dye composition for keratinous fibers which contains a coupler and a developer are disclosed. The present coupler component is a novel 2-alkoxy-3,5-diaminopyridine derivative of the formula (1): wherein R1 and R2 are the same or different from each other and independently represent a hydrogen atom, a lower alkanoyl group or a lower alkyl group which may be substituted by at least one hydroxyl group, and R3 is a lower alkyl group which may be substituted by at least one hydroxyl group, or a salt thereof; provided that R1 and R2 are not both a hydrogen atom or an acetyl group at the same time. The present 2-alkoxy-3,5-diaminopyridine derivatives are useful as couplers in dye compositions, and are capable of dyeing keratinous fibers such as hair in a bright blue color with excellent dyeability. Dye compositions containing the present compounds as a coupler show excellent resistance to discoloration, excellent resistance to shampooing and excellent resistance to friction.

  本发明公开了一种用于角质纤维的染料组合物，其中包含一种偶联剂和一种显影剂。本偶联剂成分是一种新型的 2-烷氧基-3,5-二氨基吡啶衍生物，其式为 (1)： 其中 R1 和 R2 彼此相同或不同，并独立代表氢原子、低级烷酰基或可被至少一个羟基取代的低级烷基，R3 是可被至少一个羟基取代的低级烷基或其盐；条件是 R1 和 R2 不能同时代表氢原子或乙酰基。本发明的 2-烷氧基-3,5-二氨基吡啶衍生物可用作染料组合物中的偶联剂，能够将头发等角质纤维染成具有优异染色性的亮蓝色。含有本化合物作为偶联剂的染料组合物具有优异的抗褪色性、优异的抗洗发性和优异的抗摩擦性。