N~2~-Acetyl-N-methyl-D-cysteinamide | 53023-38-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N~2~-Acetyl-N-methyl-D-cysteinamide
• 英文别名: (2S)-2-acetamido-N-methyl-3-sulfanylpropanamide
• CAS: 53023-38-4
• 化学式: C₆H₁₂N₂O₂S
• 分子量: 176.24
• InChiKey: RAHKYMLIVZZMIH-RXMQYKEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  59.2
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS
  申请人：Goldstein Glenn A.

  公开号：US20090234011A1

  公开（公告）日：2009-09-17

  Methods and compositions comprising N-acetylcysteine amide (NAC amide) and derivatives thereof are used in treatments and therapies for human and non-human mammalian diseases, disorders, conditions and pathologies. Pharmaceutically or physiologically acceptable compositions of NAC amide or derivatives thereof are administered alone, or in combination with other suitable agents, to reduce, prevent, or counteract oxidative stress and free radical oxidant formation and overproduction in cells and tissues, as well as to provide a new source of glutathione.
• N-ACETYLCYSTEINE AMIDE (NAC AMIDE) IN THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS
  申请人：Sentient LifeSciences, Inc.

  公开号：US20150164830A1

  公开（公告）日：2015-06-18

  Methods and compositions comprising N-acetylcysteine amide (NAC amide) and derivatives thereof are used in treatments and therapies for human and non-human mammalian diseases, disorders, conditions and pathologies. Pharmaceutically or physiologically acceptable compositions of NAC amide or derivatives thereof are administered alone, or in combination with other suitable agents, to reduce, prevent, or counteract oxidative stress and free radical oxidant formation and overproduction in cells and tissues, as well as to provide a new source of glutathione.
• US8354449B2
  申请人：——

  公开号：US8354449B2

  公开（公告）日：2013-01-15
• US8937099B2
  申请人：——

  公开号：US8937099B2

  公开（公告）日：2015-01-20
• US8993627B2
  申请人：——

  公开号：US8993627B2

  公开（公告）日：2015-03-31