spiro[1,2-dihydroindene-3,2'-3H-chromene]-4'-one | 203723-15-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: spiro[1,2-dihydroindene-3,2'-3H-chromene]-4'-one
• CAS: 203723-15-3
• 化学式: C₁₇H₁₄O₂
• 分子量: 250.297
• InChiKey: HHLQGSJBLWTJSI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  spiro[1,2-dihydroindene-3,2'-3H-chromene]-4'-one 在 hydroxy(tosyloxy)iodobenzene 、 二异丁基氢化铝 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 乙腈 为溶剂， 生成 (6aS,12aS)-5,6,6a,12a-Tetrahydro-benzo[a]xanthen-12-one
  参考文献：
  名称：

  螺环化的chroman-4-ones的氧化环扩展：类胡萝卜素核心和相关的苯并氧杂蒽的合成

  摘要：

  Syntheses of dehydrorotenoid and benzoxanthone units from 2'-hydroxyacetophenone are described which feature a novel migration of spiro-substituted chroman-4-ones during their oxidative ring expansion. Conjugate reduction affords a trans B/C fused rotenoid and the related cis and trans fused tetrahydrobenzoxanthones. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(97)10646-3
• 作为产物：
  描述：

  2'-羟基苯乙酮 在 四氢吡咯 、 盐酸 、 溶剂黄146 作用下， 以 甲苯 为溶剂， 生成 spiro[1,2-dihydroindene-3,2'-3H-chromene]-4'-one
  参考文献：
  名称：

  螺环化的chroman-4-ones的氧化环扩展：类胡萝卜素核心和相关的苯并氧杂蒽的合成

  摘要：

  Syntheses of dehydrorotenoid and benzoxanthone units from 2'-hydroxyacetophenone are described which feature a novel migration of spiro-substituted chroman-4-ones during their oxidative ring expansion. Conjugate reduction affords a trans B/C fused rotenoid and the related cis and trans fused tetrahydrobenzoxanthones. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(97)10646-3

文献信息

• The oxidative ring expansion of spiro-annulated chroman-4-ones: Syntheses of the rotenoid core and related benzoxanthones
  作者：Christopher D. Gabbutt、John D. Hepworth、B. Mark Heron、Jean-Luc Thomas

  DOI：10.1016/s0040-4039(97)10646-3

  日期：1998.2

  Syntheses of dehydrorotenoid and benzoxanthone units from 2'-hydroxyacetophenone are described which feature a novel migration of spiro-substituted chroman-4-ones during their oxidative ring expansion. Conjugate reduction affords a trans B/C fused rotenoid and the related cis and trans fused tetrahydrobenzoxanthones. (C) 1998 Elsevier Science Ltd. All rights reserved.