1,1-diphenylethyl methyl sulfide | 54851-63-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1-diphenylethyl methyl sulfide
• 英文别名: [1-(Methylsulfanyl)-1-phenylethyl]benzene；(1-methylsulfanyl-1-phenylethyl)benzene
• CAS: 54851-63-7
• 化学式: C₁₅H₁₆S
• 分子量: 228.358
• InChiKey: OBGKERUAGWLIGQ-UHFFFAOYSA-N

物化性质

• 沸点：
  320.6±11.0 °C(Predicted)
• 密度：
  1.053±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  甲基碘化镁 、 1,1-diphenylethyl methyl sulfide 在 bis(triphenylphosphine)nickel(II) chloride 作用下， 以 四氢呋喃 为溶剂， 反应 16.0h， 以41%的产率得到1,1-二苯乙烯
  参考文献：
  名称：

  Nickel-catalyzed olefination of cyclic benzylic dithioacetals by Grignard reagents. Scope and mechanism

  摘要：

  The details of the first nickel-catalyzed olefination of cyclic dithioacetals to form substituted styrenes and aryl-substituted 1,4-pentadienes are described. The reaction represents a new synthetic use of the dithioacetal functionality. Only nickel complexes catalyzed these cross-coupling reactions; palladium complexes displayed no catalytic activity under the reaction conditions employed. Selective coupling occurred. A mechanism for the reaction is proposed. The experimental evidence indicates that, in these nickel-catalyzed couplings, cyclic dithioacetals are more reactive than their acyclic analogues. This increased reactivity appears to be the result of maintaining the two sulfur atoms in close proximity to each other by the use of a short chain of methylene groups.

  DOI：

  10.1021/jo00012a043
• 作为产物：
  描述：

  二苯基甲烷硫酮 、 碘甲烷 反应 3.0h， 以82%的产率得到1,1-diphenylethyl methyl sulfide
  参考文献：
  名称：

  Ytterbium Metal Mediated Desulfurization and Coupling Reaction of Diaryl Thioketones

  摘要：

  二芳基硫酮可选择性地通过镱金属还原为二芳基甲硫醇、二芳基甲烷或四芳基乙烯，这一过程涉及硫金属中间体，在硫羰基的碳和硫原子处发生亲电子偶联反应。

  DOI：

  10.1246/cl.1994.611

文献信息

• ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
  申请人：Universal Display Corporation

  公开号：US20160072082A1

  公开（公告）日：2016-03-10

  Imidazophenanthridine ligands and metal complexes are provided. The compounds exhibit improved stability through a linking substitution that links a nitrogen bonded carbon of an imidizole ring to a carbon on the adjacent fused aryl ring. The compounds may be used in organic light emitting devices, particularly as emissive dopants, providing devices with improved efficiency, stability, and manufacturing. In particular, the compounds provided herein may be used in blue devices having high efficiency.

  提供了咪唑菲啉配体和金属配合物。这些化合物通过连接取代基展现出改善的稳定性，该连接将咪唑环的氮键合碳与相邻融合芳基环上的碳连接起来。这些化合物可以用于有机发光器件，特别是作为发射杂质，为设备提供改善的效率、稳定性和制造工艺。具体来说，本文提供的化合物可以用于具有高效率的蓝色器件。
• SELF-POWERED ENZYME MICROPUMPS
  申请人：THE PENN STATE RESEARCH FOUNDATION

  公开号：US20170065728A1

  公开（公告）日：2017-03-09

  Drug delivery devices, sensors, and micropumps provided herein can utilize a reaction of an analyte triggered by an enzyme to drive fluid flow. In some cases, a drug delivery device can include a reservoir including a drug (e.g., insulin) and have an enzyme (e.g., glucose oxidase) positioned adjacent to said reservoir. The enzyme can catalyze a reaction of said analyte to drive a fluid flow adjacent to said reservoir to increase a release of the drug from said reservoir. A sensor for an analyte can include an enzyme bound to a surface and a flow meter to detect a flow of fluids adjacent to said surface. A self-powered enzyme micropump provided herein can provide precise control over flow rate in response to specific signals.

  药物输送装置、传感器和微泵可以利用酶触发的分析物反应来驱动流体流动。在某些情况下，药物输送装置可以包括一个包含药物（例如胰岛素）的储液槽，并且在该储液槽旁边放置一个酶（例如葡萄糖氧化酶）。该酶可以催化所述分析物的反应，以驱动靠近所述储液槽的流体流动，从而增加从所述储液槽释放药物。用于分析物的传感器可以包括与表面结合的酶和流量计，以检测靠近所述表面的流体流动。本文提供的自供电酶微泵可以根据特定信号实现对流速的精确控制。
• Ytterbium Metal Mediated Desulfurization and Coupling Reaction of Diaryl Thioketones
  作者：Yoshikazu Makioka、Shin-ya Uebori、Masumi Tsuno、Yuki Taniguchi、Ken Takaki、Yuzo Fujiwara

  DOI：10.1246/cl.1994.611

  日期：1994.3

  Diaryl thioketones are selectively reduced with ytterbium metal to diarylmethanethiols, diarylmethanes or tetraarylethylenes, via thiometallacycle intermediates which undergo electrophilic coupling at thiocarbonyl carbon and sulfur.

  二芳基硫酮可选择性地通过镱金属还原为二芳基甲硫醇、二芳基甲烷或四芳基乙烯，这一过程涉及硫金属中间体，在硫羰基的碳和硫原子处发生亲电子偶联反应。
• Organic electroluminescent materials and devices
  申请人：Universal Display Corporation

  公开号：US10403830B2

  公开（公告）日：2019-09-03

  An organic light emitting device (OLED) is provided. The OLED has an anode, a cathode, and an emission layer, disposed between the anode and the cathode, including a first emitting compound; wherein the first emitting compound is capable of functioning as a blue phosphorescent emitter in the OLED at room temperature; wherein the first emitting compound has PLQY of less than 90% at room temperature; wherein the OLED has an external quantum efficiency of between 8% and 20% at 1 mA/cm2.

  本文提供了一种有机发光器件（OLED）。该 OLED 具有阳极、阴极和发射层，发射层设置在阳极和阴极之间，包括第一发射化合物；其中，第一发射化合物能够在室温下作为 OLED 中的蓝色磷光发射器发挥作用；其中，第一发射化合物在室温下的 PLQY 小于 90%；其中，OLED 在 1 mA/cm2 时的外部量子效率介于 8% 和 20% 之间。
• Synthetic Utility of Umpoled Diaryl Thioketone−Lanthanoid Intermediates:  Desulfurization, Cross Coupling with Electrophiles, and Desulfurizative Homocoupling
  作者：Yoshikazu Makioka、Shin-ya Uebori、Masumi Tsuno、Yuki Taniguchi、Ken Takaki、Yuzo Fujiwara

  DOI：10.1021/jo951355h

  日期：1996.1.1