2,2'-[(2-methylpentane-1,5-diyl)diimino]dibutanedioic acid tetraethyl ester | 168253-59-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,2'-[(2-methylpentane-1,5-diyl)diimino]dibutanedioic acid tetraethyl ester
• 英文别名: tetraethyl 2,2'-((2-methylpentane-1,5-diyl)bis(azanediyl))disuccinate；tetraethyl 2,2'-[(2-methylpentane-1,5-diyl)diimino]dibutanedioate；1,5-bis[1,2-bis(ethoxycarbonyl)ethylamino]-2-methylpentane；Aspartic acid, N,N'-(2-methyl-1,5-pentanediyl)bis-, 1,1',4,4'-tetraethyl ester；diethyl 2-[[5-[(1,4-diethoxy-1,4-dioxobutan-2-yl)amino]-4-methylpentyl]amino]butanedioate
• CAS: 168253-59-6
• 化学式: C₂₂H₄₀N₂O₈
• 分子量: 460.568
• InChiKey: IIXYXWPAODWTJR-UHFFFAOYSA-N

物化性质

• 沸点：
  114℃[at 101 325 Pa]
• 密度：
  1.07[at 20℃]
• LogP：
  3.7 at 25℃
• 物理描述：
  Liquid

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  32
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  129
• 氢给体数：
  2
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  1,5-二氨基-2-甲基戊烷 、 but-2-enedioic acid diethyl ester 在 氧气 作用下， 反应 4.0h， 生成 2,2'-[(2-methylpentane-1,5-diyl)diimino]dibutanedioic acid tetraethyl ester
  参考文献：
  名称：

  一种制备聚天门冬氨酸酯的方法

  摘要：

  本发明公开一种制备聚天门冬氨酸酯的方法。所述方法以负载型锌催化剂，催化有机伯胺与不饱和二元酸酯进行Michael加成反应得到。制备的负载型锌催化剂不仅显著提高了伯胺和丁烯二酸酯的反应活性，反应结束后经过滤即可对催化剂实现分离。本发明所述方法具有催化活性好、伯胺转化率高、操作简便、产品品质高等优点。

  公开号：

  CN110183335B

文献信息

• 一种聚天门冬氨酸酯的制备方法
  申请人：万华化学集团股份有限公司

  公开号：CN107805207B

  公开（公告）日：2020-01-31

  本发明提供了一种合成聚天门冬氨酸酯的方法，以四烷基氢氧化铵为催化剂，有机伯胺与不饱和二元酸酯反应得到。四烷基氢氧化铵作为有机强碱，可以明显提高伯胺和丁烯二酸酯的Michael加成反应活性，反应完成后通过简单加热即可完全脱除催化剂，不会对产品下游应用产生不利影响。本发明所述方法具有催化活性高，伯胺转化率高，产品色度低，无催化剂残留等优点。
• MEDICAL ADHESIVE FOR STEMMING BLEEDING
  申请人：Heckroth Heike

  公开号：US20140065091A1

  公开（公告）日：2014-03-06

  The present invention relates to a polyurea system comprising as component A) isocyanate-functional prepolymers obtainable by reaction of aliphatic isocyanates A1) with polyols A2), which in particular can have a number-average molecular weight of ≧400 g/mol and a mean OH functionality of from 2 to 6, as component B) an amino-functional compound of the general formula (I) in which X is an organic radical containing a secondary amino function, Y is an organic radical that contains a tertiary amino group and does not contain Zerewitinoff-active hydrogen, R 1 is a CH 2 —COOR 3 radical in which R 3 is an organic radical that does not contain Zerewitinoff-active hydrogen, a linear or branched C1- to C4-alkyl radical, a cyclopentyl radical, a cyclohexyl radical or H, R 2 is an organic radical that does not contain Zerewitinoff-active hydrogen, a is 1 or 2, b is 1 or 2, and a+b=2 or 3, for stemming the escape of blood, and to a metering system for the polyurea system according to the invention.

  本发明涉及一种聚脲系统，其中包括组分A）与脂肪族异氰酸酯A1）和聚醚醇A2）反应得到的含有异氰酸基的预聚物，特别是聚醚醇的数均分子量≧400 g/mol，平均羟基官能团从2到6；组分B）为一般式（I）中含有二级氨基的有机基团X，含有三级氨基团且不含Zerewitinoff活性氢的有机基团Y，R1为CH2—COOR3基团，其中R3为不含Zerewitinoff活性氢的有机基团、线性或支链C1-C4烷基基团、环戊基、环己基或H，R2为不含Zerewitinoff活性氢的有机基团，a为1或2，b为1或2，且a+b=2或3，用于止血，以及本发明的聚脲系统的计量系统。
• Medical adhesive for stemming bleeding
  申请人：Heckroth Heike

  公开号：US09393345B2

  公开（公告）日：2016-07-19

  The present invention relates to a polyurea system comprising as component A) isocyanate-functional prepolymers obtainable by reaction of aliphatic isocyanates A1) with polyols A2), which in particular can have a number-average molecular weight of ≧400 g/mol and a mean OH functionality of from 2 to 6, as component B) an amino-functional compound of the general formula (I) in which X is an organic radical containing a secondary amino function, Y is an organic radical that contains a tertiary amino group and does not contain Zerewitinoff-active hydrogen, R1 is a CH2—COOR3 radical in which R3 is an organic radical that does not contain Zerewitinoff-active hydrogen, a linear or branched C1- to C4-alkyl radical, a cyclopentyl radical, a cyclohexyl radical or H, R2 is an organic radical that does not contain Zerewitinoff-active hydrogen, a is 1 or 2, b is 1 or 2, and a+b=2 or 3, for stemming the escape of blood, and to a metering system for the polyurea system according to the invention.

  本发明涉及一种聚氨酯系统，其包括以下组分：A）由脂肪族异氰酸酯A1）与聚醇A2）反应得到的含有异氰酸酯官能基的预聚物，其中聚醇A2）的数量平均分子量≧400 g/mol，平均OH官能团为2至6；B）一种具有通式（I）的氨基官能化合物，其中X是含有二级胺官能团的有机基团，Y是含有三级胺基团且不含Zerewitinoff活性氢的有机基团，R1是CH2-COOR3基团，其中R3是不含Zerewitinoff活性氢的有机基团，线性或支链的C1-C4烷基基团，环戊基，环己基或H，R2是不含Zerewitinoff活性氢的有机基团，a为1或2，b为1或2，a+b=2或3，用于止血，以及根据本发明的聚氨酯系统的计量系统。
• Siloxane-based coatings containing polymers with urea linkages and terminal alkoxysilanes
  申请人：The United States of America, as represented by the Secretary of the Navy

  公开号：US10190020B2

  公开（公告）日：2019-01-29

  Polyureas made from amino-functional alkoxysilanes, polyisocyanates, and polyfunctional amino- and/or hydroxyl compounds. The polyureas may be moisture-cured in a 1K system or be included in a 2K system with amino and epoxy or acrylate compounds.

  由氨基官能团烷氧基硅烷、多异氰酸酯和多官能团氨基和/或羟基化合物制成的聚氨酯。聚脲可以在 1K 系统中进行湿气固化，也可以在 2K 系统中加入氨基和环氧或丙烯酸酯化合物。
• Magnetic floor surface
  申请人：!OBAC Limited

  公开号：US10720270B2

  公开（公告）日：2020-07-21

  The present invention is directed to a method for providing a surface, in particular a floor surface, with a layer of a magnetic and/or magnetizable cover composition, the surface having at least one layer of cementitious material, wherein the method comprises the step of spreading the layer of the cover composition onto the surface, the cover composition comprising a polymeric binder and magnetic and/or magnetizable particles, characterized in that the layer of the cover composition has a water vapor transmission rate of at least 0.25 g h−1 m−2 according to ASTM D1653, and the surface and/or the layer of cementitious material has a relative humidity of more than 75% according to ASTM F 2170-11.

  本发明涉及一种为表面，特别是地板表面提供一层磁性和/或可磁化覆盖组合物的方法，该表面至少有一层胶凝材料，其中该方法包括将覆盖组合物层铺到表面的步骤，覆盖组合物包括聚合物粘合剂和磁性和/或可磁化颗粒，其特征在于，根据 ASTM D1653，覆盖组合物层的水蒸气透过率至少为 0.根据 ASTM D1653 标准，水蒸气透过率至少为 0.25 g h-1 m-2，根据 ASTM F 2170-11 标准，表面和/或水泥基材料层的相对湿度大于 75%。