phenyl(carboxymethyl)phosphinate | 14406-31-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phenyl(carboxymethyl)phosphinate
• 英文别名: (hydroxy-phenyl-phosphinoyl)-acetic acid；(Hydroxy-phenyl-phosphinoyl)-essigsaeure；Carboxymethyl-phenyl-phosphinsaeure；Phenylphosphonessigsaeure；Phenylphosphonyl-essigsaeure, Phenyl-carboxymethylphosphinsaeure；Phenyl-carboxymethyl-phosphinsaeure；2-[Hydroxy(phenyl)phosphoryl]acetic acid
• CAS: 14406-31-6
• 化学式: C₈H₉O₄P
• mdl: MFCD01233119
• 分子量: 200.131
• InChiKey: FGALVVBOIVDPLP-UHFFFAOYSA-N

物化性质

• 熔点：
  120-122 °C
• 沸点：
  526.1±42.0 °C(Predicted)
• 密度：
  1.41±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.125
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  beryllium(II) sulphate tetrahydrate 、 phenyl(carboxymethyl)phosphinate 以 水 为溶剂， 生成 Be(phenyl(carboxymethyl)phosphinate)(H₂O)2 、 Be(phenyl(carboxymethyl)phosphinate)(H₂O)3⁽¹⁺⁾ 、 Be(phenyl(carboxymethyl)phosphinate)2^(2-)
  参考文献：
  名称：

  Complexation of Beryllium(II) Ion by Phosphinate Ligands in Aqueous Solution. Synthesis and XRPD Structure Determination of Be[(PhPO₂)₂CH₂](H₂O)₂

  摘要：

  Two bifunctional ligands, phenyl(carboxymethyl)phosphinate (ccp(2-)) and P,P'-diphenylmethylenediphosphinate (pcp(2-)), have been tested as chelating agents of beryllium(II). Both ligands have the same charge and a similar chelating structure, but whereas the 1:1 adduct of pcp(2-), Be(pcp)((HO)-O-2)(2), could be isolated as a white powder, no pure compound could be isolated from solutions containing beryllium(II) and ccp(2-). Instead, the solutions were examined by means of potentiometry and Be-9 NMR spectroscopy. Analysis of the potentiometric titration data with the program HYPERQUAD suggested the formation of the complex species BeL, [BeHL](+), [BeL2](2-), and [BeHL2](-) (L = ccp). The formation constants for these species were determined at 25 degreesC and / = 0.5 mol dm(-3) NaCIO4. The Be-9 NIVIR spectra are consistent with this model. The formation constants found for the ccp(2-) complexes are lower than those reported for related phosphonate ligands. However, the effective stability constant (which gives a better indication of the intrinsic coordinating capacity of the ligand at a particular pH) of the complex [Be(ccp)(2)](2-) at pH < 4 is greater than the effective constants of the corresponding phosphonoacetate and methylenediphosphonate complexes. The structure of Be(pcp)(H2O)(2) was determined by X-ray powder diffraction methods and consists of discrete molecules interconnected by an extended 2D network of hydrogen bonds, resulting in a stacking of double layers with a polar core and a lipophilic surface. Crystal data: C13H16BeO6P2, fw 339.21, monoclinic P2(1)/c, a 16.174(1) Angstrom, b = 8.979(1) Angstrom, c = 10.929(1) Angstrom, beta = 90.398(9)degrees, V = 1587.2(3) Angstrom(3), Z = 4.

  DOI：

  10.1021/ic0261979
• 作为产物：
  描述：

  Phenyl-ethoxycarbonylmethyl-phosphinsaeure-isobutylester 在 盐酸 作用下， 生成 phenyl(carboxymethyl)phosphinate
  参考文献：
  名称：

  Arbusow; Arbusow, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1929, vol. 61, p. 1603

  摘要：

  DOI：

文献信息

• Synthesis and anti-herpes simplex activity of analogs of phosphonoacetic acid
  作者：Thomas R. Herrin、John S. Fairgrieve、Robert R. Bower、Nathan L. Shipkowitz、James C. H. Mao

  DOI：10.1021/jm00215a008

  日期：1977.5

  The synthesis of monoesters (P and C) of phosphonoacetic acid (PA) is given. The carboxyl esters were prepared by two methods: the reaction of chloroacetates with tris(trimethylsilyl) phosphite, followed by hydrolysis; and by the acid-catalyzed esterification of PA with the appropriate alcohol. P-Monoesters of PA were prepared either by the reaction of alkyl[bis(trimethylsilyl)] phosphite with benzyl

  给出了膦酰乙酸（PA）的单酯（P和C）的合成。羧基酯是通过两种方法制备的：氯乙酸酯与亚磷酸三（三甲基甲硅烷基）酯的反应，然后水解。以及通过PA与适当的醇进行酸催化的酯化反应。通过烷基[双（三甲基甲硅烷基）]亚磷酸酯与氯乙酸苄酯的反应，然后脱保护，或使亚磷酸二甲基苯基酯与溴乙酸苄酯的反应，然后进行氢解，可以制备PA的P-单酯。报道了三种芳基-（烷基-）次膦酸衍生物。评价上述化合物对HSV诱导的DNA聚合酶和感染疱疹性皮炎的动物的抗疱疹活性。
• Mono or biaxially oriented, flame-retardant polyester film
  申请人：Joo Jae-Suk

  公开号：US20050107508A1

  公开（公告）日：2005-05-19

  The mono or biaxially oriented polyester film of the present invention having improved flame-retardancy and processibility comprises a polyester resin having an intrinsic viscosity of 0.4 to 0.9 dl/g which contains, in its polyester chain derived from dicarboxylic acid and diol components, an incorporated repeat unit of formula (I) in an amount of 10 to 30 mol % based on the amount of dicarboxylic acid, and a flame-retardancy enhancing agent in an amount ranging from 0.05 to 5% by weight based on the weight of the polyester resin.

  本发明的单向或双向拉伸聚酯薄膜具有更好的阻燃性和加工性，它包括一种本征粘度为 0.4 至 0.9 dl/g 的聚酯树脂。9 dl/g 的聚酯树脂，其聚酯链由二羧酸和二元醇组分组成，其中含有式(I)的掺合重复单元，其含量为二羧酸含量的 10 至 30 摩尔%，以及阻燃增强剂，其含量为聚酯树脂重量的 0.05 至 5%。
• Henning,H.-G., Journal fur praktische Chemie (Leipzig 1954), 1966, vol. 31, p. 304 - 311
  作者：Henning,H.-G.

  DOI：——

  日期：——
• FLAME-RETARDANT POLYESTER FILM AND METHOD FOR MANUFACTURING THE SAME
  申请人：NAN YA PLASTICS CORPORATION

  公开号：US20220017707A1

  公开（公告）日：2022-01-20

  A flame-retardant polyester film and a method for manufacturing the same are provided. The flame-retardant polyester film includes a physically recycled polyester resin and a chemically recycled polyester resin. The physically recycled polyester resin is formed by a plurality of physically recycled polyester chips. The chemically recycled polyester resin is formed by a plurality of chemically recycled polyester chips and mixed with the physically recycled polyester resin. The plurality of chemically recycled polyester chips further includes chemically recycled electrostatic pinning polyester chips. The chemically recycled electrostatic pinning polyester chips contain electrostatic pinning additives, and the electrostatic pinning additives are metal salts. Expressed in percent by weight based on a total weight of the polyester film, a content of the electrostatic pinning additives in the polyester film is between 0.005% and 0.1% by weight. The flame-retardant polyester film further includes a flame-retardant additive.
• US3941752A
  申请人：——

  公开号：US3941752A

  公开（公告）日：1976-03-02