2-(氨基甲基)戊烷二酸 | 13734-58-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2-(氨基甲基)戊烷二酸
• 英文名称: 5-Amino-4-carboxyvaleriansaeure
• 英文别名: 2-(Aminomethyl)pentanedioic acid
• CAS: 13734-58-2
• 化学式: C₆H₁₁NO₄
• 分子量: 161.158
• InChiKey: LFKXMUNHFXEROA-UHFFFAOYSA-N

物化性质

• 熔点：
  160 °C (decomp)(Solv: water (7732-18-5))
• 沸点：
  343.1±32.0 °C(Predicted)
• 密度：
  1.333±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -3.6
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  101
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Protecting group for carboxylic acids that can be photolyzed by visible light
  申请人：Hess P. George

  公开号：US20070243519A1

  公开（公告）日：2007-10-18

  The present invention relates to a photolabile compound including a coumarin family caging group covalently bound to an organic moiety containing a carboxyl group, an amino group, a sulfhydryl group, and/or a hydroxyl group. The photolabile compound, upon absorbing visible light, releases the organic moiety. Also disclosed is a method of making a photolabile compound that releases a biologically active compound upon absorbing visible light by providing an organic moiety and binding a coumarin family caging group to the organic moiety under conditions effective to make the photolabile compound. The present invention also relates to a method of obtaining a biologically active compound in a sample. The method involves adding to a sample a photolabile compound including a coumarin family caging group covalently bound to an organic moiety. The sample is then illuminated with visible light under conditions effective to obtain a biologically active compound including the organic moiety.

  本发明涉及一种光敏化合物，包括与含有羧基、氨基、巯基和/或羟基的有机基团共价结合的香豆素家族笼罩基团。该光敏化合物在吸收可见光时释放有机基团。同时还公开了一种制备光敏化合物的方法，该方法在有效条件下提供有机基团，并将香豆素家族笼罩基团与有机基团结合，以制备光敏化合物，该光敏化合物吸收可见光后释放生物活性化合物。本发明还涉及一种获取样品中生物活性化合物的方法。该方法涉及向样品中添加包括香豆素家族笼罩基团共价结合的有机基团的光敏化合物。然后在有效条件下用可见光照射样品，以获取包括有机基团的生物活性化合物。
• 1-(N-Formylamino)-2,4-dicyanobutan und ein Verfahren zu dessen Herstellung
  申请人：BAYER AG

  公开号：EP0336185B1

  公开（公告）日：1992-09-02
• Methods, Devices, and Systems for Glycated Hemoglobin Analysis
  申请人：Chinnayelka Swetha

  公开号：US20110269147A1

  公开（公告）日：2011-11-03

  Methods, devices, and systems for measuring the concentration of glycated hemoglobin (HbA 1 c) in a blood sample are provided. A blood sample may be contacted with a lysing agent, an assay to measure total Hb, and an assay to measure HbA 1 c, which comprises donor and acceptor dyes attached to a Hb specific antibody and a HbA 1 c analog. Preferably, the emission spectrum of the donor dye overlaps with the excitation spectrum of the acceptor dye. The concentration of HbA 1 c in the sample may be correlated with an increase in donor dye and/or a decrease in acceptor dye fluorescence in the presence of HbA 1 c as compared to the donor and/or the acceptor dye fluorescence in the absence of HbA 1 c.
• TRANSDERMAL SYSTEMS, DEVICES, AND METHODS TO OPTICALLY ANALYZE AN ANALYTE
  申请人：Chinnayelka Swetha

  公开号：US20120258467A1

  公开（公告）日：2012-10-11

  The invention provides transdermal optical analysis systems, test sensors, methods, and kits for determining the presence and/or concentration of at least one analyte in a fluid sample. The system includes a transdermal test sensor including an aqueous material including at least one analyte selective reagent and at least one optically active moiety. The optical system preferably uses fluorescent spectroscopy to correlate fluorescent emission or adsorption from a dye with the analyte concentration of the sample. An optical light source and/or detector may be housed with the aqueous material in a housing or external to the housing of the aqueous material.
• TRANSDERMAL SYSTEMS, DEVICES, AND METHODS FOR BIOLOGICAL ANALYSIS
  申请人：Fei Jiangfeng

  公开号：US20120252046A1

  公开（公告）日：2012-10-04

  A transdermal test sensor includes a test chamber including a liquid, a reagent system in contact with the liquid, a housing containing the liquid, and a semipermeable membrane. The housing includes an opening, the semipermeable membrane is connected to the housing and covers the opening, and the housing and the semipermeable membrane enclose the liquid and the reagent system. The transdermal test sensor also includes an analyzer in communication with the liquid. When porated tissue is contacted with the semipermeable membrane and sufficient time is allowed for a fluid sample to traverse the porated tissue and for an analyte in the fluid sample to enter the liquid in the transdermal sensor through the semipermeable membrane, a change in at least one optical property or at least one electrical property of the liquid is detected. The change detected is then correlated with the analyte concentration in the fluid sample.